MX9705460A - Procedimiento de preparacion de trihidarto de (2r,3s)-3-benzoilamino-2-hidroxi-3-fenilpropionato de 4, 10-diacetoxi- 2 alfa-benzoiloxi-5beta, 20-epoxi-1,7 beta-dihidroxi-9-oxo-tax-11-en-13alfa-ilo. - Google Patents

Procedimiento de preparacion de trihidarto de (2r,3s)-3-benzoilamino-2-hidroxi-3-fenilpropionato de 4, 10-diacetoxi- 2 alfa-benzoiloxi-5beta, 20-epoxi-1,7 beta-dihidroxi-9-oxo-tax-11-en-13alfa-ilo.

Info

Publication number
MX9705460A
MX9705460A MX9705460A MX9705460A MX9705460A MX 9705460 A MX9705460 A MX 9705460A MX 9705460 A MX9705460 A MX 9705460A MX 9705460 A MX9705460 A MX 9705460A MX 9705460 A MX9705460 A MX 9705460A
Authority
MX
Mexico
Prior art keywords
beta
alpha
diacetoxy
benzoylamino
benzoyloxy
Prior art date
Application number
MX9705460A
Other languages
English (en)
Other versions
MXPA97005460A (es
Inventor
Jean-Rene Authelin
Eric Didier
Franck Leveiller
Isabelle Taillepied
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of MX9705460A publication Critical patent/MX9705460A/es
Publication of MXPA97005460A publication Critical patent/MXPA97005460A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Se describe un procedimiento para la preparacion del trihidrato de (2R, 3S)-3-benzoilamino-2-hidroxi-3-fenilpropionato de 4,10-diacetoxi-2alfa-benzoiloxi-5 beta, 20-epoxi-1, 7 beta-dihidroxi-9-oxo-tax-11-en-13alfa-ilo mediante cristalizacion a partir de una solucion hidroalcoholica.
MXPA/A/1997/005460A 1995-01-25 1997-07-18 Procedimiento de preparacion de trihidrato de (2r,3s)-3-benzoilamino-2-hidroxi-3-fenilpropionato de4, 10-diacetoxi- 2alfa-benzoiloxi-5beta;20-epoxi-1, 7beta-dihidroxi-9-oxo-tax-11-en-13alfa-ilo MXPA97005460A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR95/00816 1995-01-25
FR9500816A FR2729666A1 (fr) 1995-01-25 1995-01-25 Procede de preparation du trihydrate du (2r, 3s)- benzoylamino-2-hydroxy-3-phenylpropionate de 4,10-diacetoxy- 2alpha-benzoyloxy-5beta,20-epoxy-1,7beta-dihydroxy-9-oxo- tax-11-en-13alpha-yle
FR9500816 1995-01-25
PCT/FR1996/000104 WO1996022984A1 (fr) 1995-01-25 1996-01-23 PROCEDE DE PREPARATION DU TRIHYDRATE DU (2R,3S)-3-BENZOYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DE 4,10-DIACETOXY-2α-BENZOYLOXY-5β,20-EPOXY-1,7β-DIHYDROXY-9-OXO-TAX-11-EN-13α-YLE

Publications (2)

Publication Number Publication Date
MX9705460A true MX9705460A (es) 1997-10-31
MXPA97005460A MXPA97005460A (es) 1998-07-03

Family

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Also Published As

Publication number Publication date
RO115728B1 (ro) 2000-05-30
EE03396B1 (et) 2001-04-16
RU2154642C2 (ru) 2000-08-20
PE64896A1 (es) 1997-02-23
NZ300958A (en) 1999-09-29
NO973247L (no) 1997-07-11
AP750A (en) 1999-07-06
ZA96523B (en) 1996-10-15
FI973105A0 (fi) 1997-07-24
MA23782A1 (fr) 1996-10-01
DK0805806T3 (da) 2000-05-01
CZ287079B6 (en) 2000-08-16
KR100384773B1 (ko) 2003-08-21
EE9700157A (et) 1997-12-15
FI119245B (fi) 2008-09-15
WO1996022984A1 (fr) 1996-08-01
BR9606853A (pt) 1997-11-25
AU4625596A (en) 1996-08-14
US6002022A (en) 1999-12-14
GR3032110T3 (en) 2000-03-31
FR2729666B1 (es) 1997-02-28
OA10438A (fr) 2002-03-22
AU707603B2 (en) 1999-07-15
JP3782449B2 (ja) 2006-06-07
SK281958B6 (sk) 2001-09-11
BG62769B1 (bg) 2000-07-31
IL116903A (en) 2003-01-12
TNSN96011A1 (fr) 2005-03-15
DZ1977A1 (fr) 2002-07-20
HUP9801437A1 (hu) 1999-09-28
NO316987B1 (no) 2004-07-19
BG101794A (en) 1998-10-30
JPH10512871A (ja) 1998-12-08
TW356469B (en) 1999-04-21
IS2033B (is) 2005-08-15
FI973105A (fi) 1997-07-24
NO973247D0 (no) 1997-07-11
PL183773B1 (pl) 2002-07-31
UY24149A1 (es) 1996-05-20
PL321493A1 (en) 1997-12-08
DE69605651T2 (de) 2000-07-06
UA47420C2 (uk) 2002-07-15
DE69605651D1 (de) 2000-01-20
MY113230A (en) 2001-12-31
HU223352B1 (hu) 2004-06-28
IL116903A0 (en) 1996-05-14
FR2729666A1 (fr) 1996-07-26
GEP19991833B (en) 1999-11-05
PT805806E (pt) 2000-05-31
ES2139332T3 (es) 2000-02-01
AP9701035A0 (en) 1997-07-31
EP0805806B1 (fr) 1999-12-15
SK100897A3 (en) 1998-01-14
CO4700286A1 (es) 1998-12-29
TR199700676T1 (xx) 1998-01-21
IN184427B (es) 2000-08-26
KR19980701623A (ko) 1998-06-25
HUP9801437A3 (en) 2001-02-28
CN1067997C (zh) 2001-07-04
EP0805806A1 (fr) 1997-11-12
CZ236297A3 (en) 1997-11-12
IS4529A (is) 1997-07-22
ATE187719T1 (de) 2000-01-15
CN1169724A (zh) 1998-01-07

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Legal Events

Date Code Title Description
FG Grant or registration
HC Change of company name or juridical status

Owner name: MACGREGOR NORWAY AS

MM Annulment or lapse due to non-payment of fees