MX9701948A - Epimeros de (22rs-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-oxo-4-aza-5alfa-androst-1-e n-17beta-carboxamida. - Google Patents

Epimeros de (22rs-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-oxo-4-aza-5alfa-androst-1-e n-17beta-carboxamida.

Info

Publication number
MX9701948A
MX9701948A MX9701948A MX9701948A MX9701948A MX 9701948 A MX9701948 A MX 9701948A MX 9701948 A MX9701948 A MX 9701948A MX 9701948 A MX9701948 A MX 9701948A MX 9701948 A MX9701948 A MX 9701948A
Authority
MX
Mexico
Prior art keywords
alpha
phenylprop
aza
trifluoro
ene
Prior art date
Application number
MX9701948A
Other languages
English (en)
Spanish (es)
Other versions
MXPA97001948A (en
Inventor
Achille Panzeri
Marcella Nesi
Enrico Di Salle
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of MXPA97001948A publication Critical patent/MXPA97001948A/xx
Publication of MX9701948A publication Critical patent/MX9701948A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX9701948A 1995-07-21 1996-06-28 Epimeros de (22rs-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-oxo-4-aza-5alfa-androst-1-e n-17beta-carboxamida. MX9701948A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
MIMI95A001587 1995-07-21
IT95MI001587A IT1275594B1 (it) 1995-07-21 1995-07-21 Epimeri del (22rs)-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-osso -4-aza-5alfa-androst-1-ene-17beta-carbossammide
PCT/EP1996/002830 WO1997004002A1 (fr) 1995-07-21 1996-06-28 EPIMERES DE (22RS)-N-(1,1,1-TRIFLUORO-2-PHENYLPROP-Y-YL)-3-OXO-4-AZA-5α-ANDROST-1-ENE-17β-CARBOXAMIDE

Publications (2)

Publication Number Publication Date
MXPA97001948A MXPA97001948A (en) 1997-06-01
MX9701948A true MX9701948A (es) 1997-06-28

Family

ID=11372032

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9701948A MX9701948A (es) 1995-07-21 1996-06-28 Epimeros de (22rs-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-oxo-4-aza-5alfa-androst-1-e n-17beta-carboxamida.

Country Status (17)

Country Link
EP (1) EP0782582A1 (fr)
JP (1) JPH10506411A (fr)
KR (1) KR970706298A (fr)
CN (1) CN1159195A (fr)
AR (1) AR003967A1 (fr)
AU (1) AU6418396A (fr)
BR (1) BR9606527A (fr)
CA (1) CA2199273A1 (fr)
EA (1) EA199700045A1 (fr)
HU (1) HUP9702465A3 (fr)
IL (1) IL120343A0 (fr)
IT (1) IT1275594B1 (fr)
MX (1) MX9701948A (fr)
NO (1) NO971196D0 (fr)
PL (1) PL319351A1 (fr)
WO (1) WO1997004002A1 (fr)
ZA (1) ZA965678B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000013509A1 (fr) * 1998-09-09 2000-03-16 Merck & Co., Inc. Procede de determination et de reduction du risque de survenue de problemes urologiques lies a l'adenome prostatique
ES2237408T3 (es) * 1999-01-25 2005-08-01 Smithkline Beecham Corporation Antiandrogenos y procedimientos para tratar una enfermedad.
CN100355772C (zh) * 2005-12-28 2007-12-19 天津大学 具有5α－还原酶抑制活性的甾体化合物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9216284D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives

Also Published As

Publication number Publication date
HUP9702465A2 (hu) 1998-05-28
EP0782582A1 (fr) 1997-07-09
HUP9702465A3 (en) 1998-11-30
ITMI951587A1 (it) 1997-01-21
CA2199273A1 (fr) 1997-02-06
ZA965678B (en) 1997-01-24
AU6418396A (en) 1997-02-18
JPH10506411A (ja) 1998-06-23
AR003967A1 (es) 1998-09-30
IL120343A0 (en) 1997-06-10
NO971196L (no) 1997-03-14
ITMI951587A0 (it) 1995-07-21
BR9606527A (pt) 1997-12-23
EA199700045A1 (ru) 1997-12-30
KR970706298A (ko) 1997-11-03
IT1275594B1 (it) 1997-08-06
CN1159195A (zh) 1997-09-10
NO971196D0 (no) 1997-03-14
PL319351A1 (en) 1997-08-04
WO1997004002A1 (fr) 1997-02-06

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