MX9605640A - Procedimiento para la obtencion de aminoacidos n-z-protegidos, n-metilados. - Google Patents

Procedimiento para la obtencion de aminoacidos n-z-protegidos, n-metilados.

Info

Publication number
MX9605640A
MX9605640A MX9605640A MX9605640A MX9605640A MX 9605640 A MX9605640 A MX 9605640A MX 9605640 A MX9605640 A MX 9605640A MX 9605640 A MX9605640 A MX 9605640A MX 9605640 A MX9605640 A MX 9605640A
Authority
MX
Mexico
Prior art keywords
protected
producing
amino acids
alkylated amino
formula
Prior art date
Application number
MX9605640A
Other languages
English (en)
Other versions
MXPA96005640A (es
Inventor
Ulrich Karl
Stefan Muller
Bernd Potzolli
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of MX9605640A publication Critical patent/MX9605640A/es
Publication of MXPA96005640A publication Critical patent/MXPA96005640A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Se describe un procedimiento para la obtencion de aminoácidos N-Z-protegidos, N-metilados de la formula I: donde los sustituyentes tienen los significados indicados en la descripcion. El procedimiento consiste en mezclar un compuesto de la formula II, con una solucion de terc-butanolato de potasio en un disolvente orgánico no protico, y luego se agrega un haluro de alquilo con 1 a 2 átomos de carbono.
MXPA/A/1996/005640A 1994-05-19 1996-11-18 Procedimiento para la obtencion de aminoacidos n-z-protegidos, n-metilados MXPA96005640A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4417478A DE4417478A1 (de) 1994-05-19 1994-05-19 Verfahren zur Herstellung N-Z-geschützter N-methylierter Aminosäuren
DEP4417478.0 1994-05-19
PCT/EP1995/001752 WO1995032180A1 (de) 1994-05-19 1995-05-09 Verfahren zur herstellung n-z-geschützter n-alkylierter aminosäuren

Publications (2)

Publication Number Publication Date
MX9605640A true MX9605640A (es) 1998-03-31
MXPA96005640A MXPA96005640A (es) 1998-10-15

Family

ID=

Also Published As

Publication number Publication date
DK0759901T3 (da) 1999-12-13
WO1995032180A1 (de) 1995-11-30
FI964607A0 (fi) 1996-11-18
KR970703303A (ko) 1997-07-03
US6218572B1 (en) 2001-04-17
HU9603189D0 (en) 1997-01-28
ATE183994T1 (de) 1999-09-15
HU221596B (hu) 2002-11-28
ES2136856T3 (es) 1999-12-01
GR3031456T3 (en) 2000-01-31
DE4417478A1 (de) 1995-11-23
DE59506734D1 (de) 1999-10-07
EP0759901B1 (de) 1999-09-01
HUT75707A (en) 1997-05-28
FI964607A (fi) 1997-01-16
CA2190656A1 (en) 1995-11-30
EP0759901A1 (de) 1997-03-05
JPH10500416A (ja) 1998-01-13
AU2562695A (en) 1995-12-18

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