ES2136856T3 - Procedimiento para la obtencion de aminoacidos n-z-protegidos n-alquilados. - Google Patents

Procedimiento para la obtencion de aminoacidos n-z-protegidos n-alquilados.

Info

Publication number
ES2136856T3
ES2136856T3 ES95920008T ES95920008T ES2136856T3 ES 2136856 T3 ES2136856 T3 ES 2136856T3 ES 95920008 T ES95920008 T ES 95920008T ES 95920008 T ES95920008 T ES 95920008T ES 2136856 T3 ES2136856 T3 ES 2136856T3
Authority
ES
Spain
Prior art keywords
protected
amino acids
rented
procedure
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95920008T
Other languages
English (en)
Inventor
Ulrich Karl
Stefan Muller
Potzolli Bernd De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2136856T3 publication Critical patent/ES2136856T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

SE DESCRIBE UN PROCEDIMIENTO PARA LA OBTENCION DE AMINOACIDOS ALQUILADOS EN N Y PROTEGIDOS EN N DE FORMULA (I), EN DONDE LOS SUSTITUYENTES TIENEN EL SIGNIFICADO DADO EN LA DESCRIPCION. EL PROCEDIMIENTO CONSISTE EN QUE A UN COMPUESTO DE FORMULA (II) SE LE AÑADE UNA SOLUCION DE BUTANOLATO TERCIARIO DE POTASIO EN UN DISOLVENTE APROTICO, Y A CONTINUACION SE AÑADE UN HALOGENURO DE ALQUILO DE C{SUB,1-2}.
ES95920008T 1994-05-19 1995-05-09 Procedimiento para la obtencion de aminoacidos n-z-protegidos n-alquilados. Expired - Lifetime ES2136856T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4417478A DE4417478A1 (de) 1994-05-19 1994-05-19 Verfahren zur Herstellung N-Z-geschützter N-methylierter Aminosäuren

Publications (1)

Publication Number Publication Date
ES2136856T3 true ES2136856T3 (es) 1999-12-01

Family

ID=6518436

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95920008T Expired - Lifetime ES2136856T3 (es) 1994-05-19 1995-05-09 Procedimiento para la obtencion de aminoacidos n-z-protegidos n-alquilados.

Country Status (14)

Country Link
US (1) US6218572B1 (es)
EP (1) EP0759901B1 (es)
JP (1) JPH10500416A (es)
KR (1) KR970703303A (es)
AT (1) ATE183994T1 (es)
AU (1) AU2562695A (es)
CA (1) CA2190656A1 (es)
DE (2) DE4417478A1 (es)
DK (1) DK0759901T3 (es)
ES (1) ES2136856T3 (es)
FI (1) FI964607A (es)
GR (1) GR3031456T3 (es)
HU (1) HU221596B (es)
WO (1) WO1995032180A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2043038A1 (en) 2007-05-08 2009-04-01 Ruben Pais Method and instruments for sale of personal care products

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1108125A (en) 1977-12-23 1981-09-01 Frank R. Atherton Olgiopeptide derivatives of phosphonic acid
AU4665289A (en) * 1988-12-22 1990-07-10 Upjohn Company, The N-alkylation of n-alpha-boc-protected amino acids
DE4337331A1 (de) * 1993-11-02 1995-05-04 Basf Ag Verfahren zur Herstellung N-geschützter N-alkylierter Aminosäuren

Also Published As

Publication number Publication date
DE59506734D1 (de) 1999-10-07
JPH10500416A (ja) 1998-01-13
CA2190656A1 (en) 1995-11-30
ATE183994T1 (de) 1999-09-15
GR3031456T3 (en) 2000-01-31
EP0759901B1 (de) 1999-09-01
HU9603189D0 (en) 1997-01-28
KR970703303A (ko) 1997-07-03
FI964607A (fi) 1997-01-16
DE4417478A1 (de) 1995-11-23
AU2562695A (en) 1995-12-18
FI964607A0 (fi) 1996-11-18
EP0759901A1 (de) 1997-03-05
WO1995032180A1 (de) 1995-11-30
MX9605640A (es) 1998-03-31
HU221596B (hu) 2002-11-28
US6218572B1 (en) 2001-04-17
HUT75707A (en) 1997-05-28
DK0759901T3 (da) 1999-12-13

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