MX9307465A - Proteinas que tienen actividad de transferasa glicosilica. - Google Patents

Proteinas que tienen actividad de transferasa glicosilica.

Info

Publication number
MX9307465A
MX9307465A MX9307465A MX9307465A MX9307465A MX 9307465 A MX9307465 A MX 9307465A MX 9307465 A MX9307465 A MX 9307465A MX 9307465 A MX9307465 A MX 9307465A MX 9307465 A MX9307465 A MX 9307465A
Authority
MX
Mexico
Prior art keywords
proteins
transferase activity
dna molecules
glycosilic
recombinant dna
Prior art date
Application number
MX9307465A
Other languages
English (en)
Inventor
Eric G Berger
Manfred Watzele
Svetoslav X Iwanow
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of MX9307465A publication Critical patent/MX9307465A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a proteínas novedosas que tienen una actividad de transferasa glicosílica, a proteínas que codifican moléculas de ADN recombinante que tienen actividad de transferasa glicosílica, a vectores híbridos que comprenden a estas moléculas de ADN recombinante, a huéspedes transformadores adecuados para la multiplicación y/o expresión de las moléculas de ADN recombinante, y a procedimientos para la preparación de las proteínas, las moléculas de ADN , y los huéspedes.
MX9307465A 1992-11-27 1993-11-26 Proteinas que tienen actividad de transferasa glicosilica. MX9307465A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92810924 1992-11-27

Publications (1)

Publication Number Publication Date
MX9307465A true MX9307465A (es) 1994-08-31

Family

ID=8212036

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9307465A MX9307465A (es) 1992-11-27 1993-11-26 Proteinas que tienen actividad de transferasa glicosilica.

Country Status (11)

Country Link
US (1) US5641668A (es)
EP (1) EP0788548A1 (es)
JP (1) JPH08503373A (es)
KR (1) KR950704497A (es)
AU (1) AU682837B2 (es)
CA (1) CA2148929A1 (es)
FI (1) FI952574A0 (es)
MX (1) MX9307465A (es)
NO (1) NO952039D0 (es)
NZ (1) NZ258525A (es)
WO (1) WO1994012646A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770420A (en) * 1995-09-08 1998-06-23 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures
ATE374816T1 (de) * 1996-08-02 2007-10-15 Austin Research Inst Verbesserte nukleinsäuren, welche für eine chimäre glycosyltransferase kodieren
US5945314A (en) * 1997-03-31 1999-08-31 Abbott Laboratories Process for synthesizing oligosaccharides
AU759792B2 (en) 1998-03-25 2003-05-01 Forschungszentrum Borstel Processive glycosyltransferase
US6586175B1 (en) 1998-07-28 2003-07-01 Dna Sciences Laboratories, Inc. Genotyping the human UDP-glucuronosyltransferase 2B7 (UGT2B7) gene
BR9917026B1 (pt) 1998-12-09 2010-10-19 método para fabricar glicoproteìnas tendo glicosilação do tipo humano.
ES2288882T3 (es) 1999-10-26 2008-02-01 Plant Research International B.V. Glicosilacion de tipo mamifero en plantas.
IL156879A0 (en) 2001-01-19 2004-02-08 Dow Chemical Co Method for secretory production of glycoprotein having human-type sugar chain using plant cell
EP2305313B1 (en) 2001-10-10 2014-03-26 ratiopharm GmbH Remodelling and glycoconjugation of interferon-alpha (IFNa)
SG177002A1 (en) 2001-10-10 2012-01-30 Novo Nordisk As Remodeling and glycoconjugation of peptides
AU2002352253A1 (en) * 2001-12-18 2003-06-30 Bayer Healthcare Ag Regulation of human sialyltransferase
JP5350573B2 (ja) 2002-03-19 2013-11-27 スティヒティング ディーンスト ランドバウクンディフ オンデルズーク 植物におけるｇｎｔｉｉｉ発現
NZ534880A (en) 2002-03-19 2008-04-30 Plant Res Int Bv Optimizing glycan processing in plants
CA2485102A1 (en) * 2002-05-03 2003-11-13 Neose Technologies, Inc. Recombinant glycosyltransferase fusion proteins
EP1539989B1 (en) 2002-07-23 2011-04-20 BioGeneriX AG Synthesis of oligosaccharides, glycolipids and glycoproteins using bacterial glycosyltransferases
AR042145A1 (es) 2002-11-27 2005-06-08 Dow Agrociences Llc Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
MXPA05010773A (es) 2003-04-09 2005-12-12 Neose Technologies Inc Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos.
CA2555109C (en) 2004-02-04 2016-12-06 Neose Technologies, Inc. Methods of refolding mammalian glycosyltransferases
MX2009011109A (es) 2007-04-17 2009-12-01 Plant Res Int Bv Glicosilación tipo mamífera en plantas para la expresión de glicosil-transferasas no mamíferas.
EP2824176A1 (en) * 2013-07-11 2015-01-14 Siamed'xpress Methods for producing sialylated therapeutic proteins
CA2954974A1 (en) 2014-07-21 2016-01-28 Glykos Finland Oy Production of glycoproteins with mammalian-like n-glycans in filamentous fungi
WO2016102569A1 (en) * 2014-12-22 2016-06-30 Veterinærinstituttet Salmon gill poxvirus
JP2018500934A (ja) * 2014-12-22 2018-01-18 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｃｍｐ依存性シアリダーゼ活性
EP3423587B1 (en) 2016-04-05 2020-06-24 Council of Scientific & Industrial Research A multifunctional recombinant nucleotide dependent glycosyltransferase protein and its method of glycosylation thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990007000A2 (en) * 1988-12-13 1990-06-28 La Jolla Cancer Research Foundation Nucleotides encoding human b1, 4-galactosyltransferase and uses thereof
US5541083A (en) * 1989-10-24 1996-07-30 The Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
DE69131925D1 (de) * 1990-02-14 2000-02-24 Univ Michigan Ann Arbor Verfahren und produkte für die synthese von oligosaccharidstrukturen auf glykoproteinen, glykolipiden oder als freie moleküle
JPH05501359A (ja) * 1990-04-27 1993-03-18 バイオジェン，インコーポレイテッド 付着分子発現に関与するフコシルトランスフェラーゼ
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen
GB2249096A (en) * 1990-10-11 1992-04-29 Ciba Geigy Saccharomyces cerevisiae strains lacking carboxypeptidase yscY activity for expression of proteins at high yields
US5461143A (en) * 1991-03-18 1995-10-24 The Scripps Research Institute Oligosaccharide enzyme substrates and inhibitors: methods and compositions

Also Published As

Publication number Publication date
JPH08503373A (ja) 1996-04-16
US5641668A (en) 1997-06-24
EP0788548A1 (en) 1997-08-13
AU5624294A (en) 1994-06-22
WO1994012646A1 (en) 1994-06-09
NZ258525A (en) 1997-05-26
AU682837B2 (en) 1997-10-23
NO952039L (no) 1995-05-23
FI952574A (fi) 1995-05-26
NO952039D0 (no) 1995-05-23
FI952574A0 (fi) 1995-05-26
CA2148929A1 (en) 1994-06-09
KR950704497A (ko) 1995-11-20

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