MX9307465A - Proteinas que tienen actividad de transferasa glicosilica. - Google Patents

Proteinas que tienen actividad de transferasa glicosilica.

Info

Publication number
MX9307465A
MX9307465A MX9307465A MX9307465A MX9307465A MX 9307465 A MX9307465 A MX 9307465A MX 9307465 A MX9307465 A MX 9307465A MX 9307465 A MX9307465 A MX 9307465A MX 9307465 A MX9307465 A MX 9307465A
Authority
MX
Mexico
Prior art keywords
proteins
transferase activity
dna molecules
glycosilic
recombinant dna
Prior art date
Application number
MX9307465A
Other languages
English (en)
Inventor
Eric G Berger
Manfred Watzele
Svetoslav X Iwanow
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of MX9307465A publication Critical patent/MX9307465A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a proteínas novedosas que tienen una actividad de transferasa glicosílica, a proteínas que codifican moléculas de ADN recombinante que tienen actividad de transferasa glicosílica, a vectores híbridos que comprenden a estas moléculas de ADN recombinante, a huéspedes transformadores adecuados para la multiplicación y/o expresión de las moléculas de ADN recombinante, y a procedimientos para la preparación de las proteínas, las moléculas de ADN , y los huéspedes.
MX9307465A 1992-11-27 1993-11-26 Proteinas que tienen actividad de transferasa glicosilica. MX9307465A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92810924 1992-11-27

Publications (1)

Publication Number Publication Date
MX9307465A true MX9307465A (es) 1994-08-31

Family

ID=8212036

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9307465A MX9307465A (es) 1992-11-27 1993-11-26 Proteinas que tienen actividad de transferasa glicosilica.

Country Status (11)

Country Link
US (1) US5641668A (es)
EP (1) EP0788548A1 (es)
JP (1) JPH08503373A (es)
KR (1) KR950704497A (es)
AU (1) AU682837B2 (es)
CA (1) CA2148929A1 (es)
FI (1) FI952574A0 (es)
MX (1) MX9307465A (es)
NO (1) NO952039L (es)
NZ (1) NZ258525A (es)
WO (1) WO1994012646A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770420A (en) * 1995-09-08 1998-06-23 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures
WO1998005768A1 (en) * 1996-08-02 1998-02-12 The Austin Research Institute Improved nucleic acids encoding a chimeric glycosyltransferase
US5945314A (en) * 1997-03-31 1999-08-31 Abbott Laboratories Process for synthesizing oligosaccharides
AU759792B2 (en) 1998-03-25 2003-05-01 Forschungszentrum Borstel Processive glycosyltransferase
US6586175B1 (en) * 1998-07-28 2003-07-01 Dna Sciences Laboratories, Inc. Genotyping the human UDP-glucuronosyltransferase 2B7 (UGT2B7) gene
EP1137789B1 (en) 1998-12-09 2010-07-28 Phyton Holdings, LLC A method for manufacturing glycoproteins having human-type glycosylation
DK1772518T3 (da) 1999-10-26 2010-11-22 Stichting Dienst Landbouwkundi Pattedyrsagtig glykosylering i planter
CA2434364C (en) 2001-01-19 2013-03-19 The Dow Chemical Company Method for secretory production of glycoprotein having human-type sugar chain using plant cell
EP2298354B1 (en) 2001-10-10 2014-03-19 ratiopharm GmbH Remodelling and glycoconjugation of interferon-beta
MXPA04003333A (es) 2001-10-10 2006-02-22 Neose Technologies Inc Remodelado y glicoconjugacion de peptidos.
WO2003052088A2 (en) * 2001-12-18 2003-06-26 Bayer Healthcare Ag Regulation of human sialyltransferase
CA2799805C (en) 2002-03-19 2016-05-17 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
EP2319935B1 (en) 2002-03-19 2016-04-27 Stichting Dienst Landbouwkundig Onderzoek GnTIII (UDP-N-acetylglucosamine:Beta -D mannoside Beta (1,4)-N-acetylglucosaminyltransferase III) expression in plants.
EP1504023A4 (en) * 2002-05-03 2006-03-22 Neose Technologies Inc RECOMBINANT GLYCOSYL TRANSFERASE FUSION PROTEINS
ATE506450T1 (de) 2002-07-23 2011-05-15 Biogenerix Ag Synthese von oligosacchariden, glykolipiden und glykoproteinen unter verwendung bakterieller glykosyltransferasen
CL2003002461A1 (es) 2002-11-27 2005-01-07 Dow Chemical Company Agroscien Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
US20070026485A1 (en) 2003-04-09 2007-02-01 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
JP4892358B2 (ja) 2004-02-04 2012-03-07 ノヴォ ノルディスク アー／エス 哺乳動物グリコシルトランスフェラーゼをリフォールディングする方法
NZ593203A (en) 2007-04-17 2012-08-31 Stichting Dienst Landbouwkundi Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases by inserting a polypeptide coding for a non-mammalian beta1,4-galactosyltransferase
EP2824176A1 (en) * 2013-07-11 2015-01-14 Siamed'xpress Methods for producing sialylated therapeutic proteins
AU2015293949B2 (en) 2014-07-21 2019-07-25 Teknologian Tutkimuskeskus Vtt Oy Production of glycoproteins with mammalian-like N-glycans in filamentous fungi
CA2971791A1 (en) * 2014-12-22 2016-06-30 Veterinaerinstituttet Salmon gill poxvirus
EP3237608B1 (en) * 2014-12-22 2019-10-09 F. Hoffmann-La Roche AG Cmp-dependent sialidase activity
WO2017175239A1 (en) 2016-04-05 2017-10-12 Council Of Scientific & Industrial Research A multifunctional recombinant nucleotide dependent glycosyltransferase protein and its method of glycosylation thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990007000A2 (en) * 1988-12-13 1990-06-28 La Jolla Cancer Research Foundation Nucleotides encoding human b1, 4-galactosyltransferase and uses thereof
US5541083A (en) * 1989-10-24 1996-07-30 The Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
JPH05504480A (ja) * 1990-02-14 1993-07-15 ザ リージェンツ オブ ザ ユニバーシティー オブ ミシガン 糖タンパク質、糖脂質上の、又は遊離分子としてのオリゴ糖構造の合成のための、並びにこれらの構造を決定するクローン化した遺伝配列の単離のための方法及び生成物
EP0485532A1 (en) * 1990-04-27 1992-05-20 Biogen, Inc. Fucosyl transferases involved in adhesion molecule expression
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen
GB2249096A (en) * 1990-10-11 1992-04-29 Ciba Geigy Saccharomyces cerevisiae strains lacking carboxypeptidase yscY activity for expression of proteins at high yields
US5461143A (en) * 1991-03-18 1995-10-24 The Scripps Research Institute Oligosaccharide enzyme substrates and inhibitors: methods and compositions

Also Published As

Publication number Publication date
CA2148929A1 (en) 1994-06-09
KR950704497A (ko) 1995-11-20
WO1994012646A1 (en) 1994-06-09
JPH08503373A (ja) 1996-04-16
FI952574A (fi) 1995-05-26
US5641668A (en) 1997-06-24
AU5624294A (en) 1994-06-22
NO952039D0 (no) 1995-05-23
FI952574A0 (fi) 1995-05-26
NZ258525A (en) 1997-05-26
EP0788548A1 (en) 1997-08-13
AU682837B2 (en) 1997-10-23
NO952039L (no) 1995-05-23

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