FI952574A - Glykosyylitransferaasiaktiiviset proteiinit - Google Patents

Glykosyylitransferaasiaktiiviset proteiinit Download PDF

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Publication number
FI952574A
FI952574A FI952574A FI952574A FI952574A FI 952574 A FI952574 A FI 952574A FI 952574 A FI952574 A FI 952574A FI 952574 A FI952574 A FI 952574A FI 952574 A FI952574 A FI 952574A
Authority
FI
Finland
Prior art keywords
active proteins
glycosyl transferase
transferase active
glycosyl
proteins
Prior art date
Application number
FI952574A
Other languages
English (en)
Swedish (sv)
Other versions
FI952574A0 (fi
Inventor
Eric G Berger
Manfred Watzele
Stetoslav X Iwanow
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI952574A publication Critical patent/FI952574A/fi
Publication of FI952574A0 publication Critical patent/FI952574A0/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI952574A 1992-11-27 1995-05-26 Glykosyylitransferaasiaktiiviset proteiinit FI952574A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92810924 1992-11-27
PCT/EP1993/003194 WO1994012646A1 (en) 1992-11-27 1993-11-15 Proteins having glycosyltransferase activity

Publications (2)

Publication Number Publication Date
FI952574A true FI952574A (fi) 1995-05-26
FI952574A0 FI952574A0 (fi) 1995-05-26

Family

ID=8212036

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952574A FI952574A0 (fi) 1992-11-27 1995-05-26 Glykosyylitransferaasiaktiiviset proteiinit

Country Status (11)

Country Link
US (1) US5641668A (fi)
EP (1) EP0788548A1 (fi)
JP (1) JPH08503373A (fi)
KR (1) KR950704497A (fi)
AU (1) AU682837B2 (fi)
CA (1) CA2148929A1 (fi)
FI (1) FI952574A0 (fi)
MX (1) MX9307465A (fi)
NO (1) NO952039L (fi)
NZ (1) NZ258525A (fi)
WO (1) WO1994012646A1 (fi)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770420A (en) * 1995-09-08 1998-06-23 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures
WO1998005768A1 (en) * 1996-08-02 1998-02-12 The Austin Research Institute Improved nucleic acids encoding a chimeric glycosyltransferase
US5945314A (en) * 1997-03-31 1999-08-31 Abbott Laboratories Process for synthesizing oligosaccharides
AU759792B2 (en) 1998-03-25 2003-05-01 Forschungszentrum Borstel Processive glycosyltransferase
US6586175B1 (en) 1998-07-28 2003-07-01 Dna Sciences Laboratories, Inc. Genotyping the human UDP-glucuronosyltransferase 2B7 (UGT2B7) gene
CA2354377C (en) 1998-12-09 2007-04-10 Tatsuji Seki A method for manufacturing glycoproteins having human-type glycosylation
DE60035285T2 (de) 1999-10-26 2008-02-21 Plant Research International B.V. Glykolisierung des säugetiertyps in pflanzen
IL156879A0 (en) 2001-01-19 2004-02-08 Dow Chemical Co Method for secretory production of glycoprotein having human-type sugar chain using plant cell
WO2004099231A2 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
DK1578771T3 (da) 2001-10-10 2013-06-10 Novo Nordisk As Remodellering og glycokonjugering af peptider
DK2279753T3 (en) 2001-10-10 2015-11-23 Novo Nordisk As The conversion of peptides and glycokonjugering
WO2003052088A2 (en) * 2001-12-18 2003-06-26 Bayer Healthcare Ag Regulation of human sialyltransferase
EP1485492B1 (en) 2002-03-19 2011-12-21 Stichting Dienst Landbouwkundig Onderzoek Gntiii (udp-n-acetylglucosamine:beta-d mannoside beta(1,4)-n-acetylglucosaminyltransferase iii) expression in plants
CA2923247A1 (en) * 2002-03-19 2003-09-25 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
WO2003093448A2 (en) * 2002-05-03 2003-11-13 Neose Technologies, Inc. Recombinant glycosyltransferase fusion proteins
ATE506450T1 (de) 2002-07-23 2011-05-15 Biogenerix Ag Synthese von oligosacchariden, glykolipiden und glykoproteinen unter verwendung bakterieller glykosyltransferasen
CL2003002461A1 (es) 2002-11-27 2005-01-07 Dow Chemical Company Agroscien Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
ATE516349T1 (de) 2004-02-04 2011-07-15 Novo Nordisk As Verfahren zur rückfaltung von säuger- glycosyltransferasen
NZ580510A (en) 2007-04-17 2011-06-30 Stichting Dienst Landbouwkundi Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
EP2824176A1 (en) * 2013-07-11 2015-01-14 Siamed'xpress Methods for producing sialylated therapeutic proteins
EP3172333B1 (en) 2014-07-21 2020-05-13 Glykos Finland Oy Production of glycoproteins with mammalian-like n-glycans in filamentous fungi
US10640752B2 (en) * 2014-12-22 2020-05-05 Veterinærinstituttet Salmon gill poxvirus
JP2018500934A (ja) * 2014-12-22 2018-01-18 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｃｍｐ依存性シアリダーゼ活性
US11485991B2 (en) 2016-04-05 2022-11-01 Council Of Scientific & Industrial Research Multifunctional recombinant nucleotide dependent glycosyltransferase protein and its method of glycosylation thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4751990A (en) * 1988-12-13 1990-07-10 La Jolla Cancer Research Foundation Nucleotides encoding human b1, 4-galactosyltransferase and uses thereof
US5541083A (en) * 1989-10-24 1996-07-30 The Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
CA2075949A1 (en) * 1990-02-14 1991-08-15 John B. Lowe Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules
EP0485532A1 (en) * 1990-04-27 1992-05-20 Biogen, Inc. Fucosyl transferases involved in adhesion molecule expression
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen
GB2249096A (en) * 1990-10-11 1992-04-29 Ciba Geigy Saccharomyces cerevisiae strains lacking carboxypeptidase yscY activity for expression of proteins at high yields
US5461143A (en) * 1991-03-18 1995-10-24 The Scripps Research Institute Oligosaccharide enzyme substrates and inhibitors: methods and compositions

Also Published As

Publication number Publication date
MX9307465A (es) 1994-08-31
CA2148929A1 (en) 1994-06-09
NZ258525A (en) 1997-05-26
WO1994012646A1 (en) 1994-06-09
NO952039D0 (no) 1995-05-23
NO952039L (no) 1995-05-23
AU682837B2 (en) 1997-10-23
KR950704497A (ko) 1995-11-20
EP0788548A1 (en) 1997-08-13
JPH08503373A (ja) 1996-04-16
AU5624294A (en) 1994-06-22
US5641668A (en) 1997-06-24
FI952574A0 (fi) 1995-05-26

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