NO952039L - Proteiner med glykosyltransferase-aktivitet - Google Patents

Proteiner med glykosyltransferase-aktivitet

Info

Publication number
NO952039L
NO952039L NO952039A NO952039A NO952039L NO 952039 L NO952039 L NO 952039L NO 952039 A NO952039 A NO 952039A NO 952039 A NO952039 A NO 952039A NO 952039 L NO952039 L NO 952039L
Authority
NO
Norway
Prior art keywords
proteins
dna molecules
glycosyltransferase activity
recombinant dna
hosts
Prior art date
Application number
NO952039A
Other languages
English (en)
Other versions
NO952039D0 (no
Inventor
Eric G Berger
Manfred Watzele
Svetoslav X Iwanow
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO952039D0 publication Critical patent/NO952039D0/no
Publication of NO952039L publication Critical patent/NO952039L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Det blir beskrevet nye proteiner med glykosyltrans- feraseaktlvltet, rekombinante DNA-molekyler som koder for proteiner med glykosyltransferaseaktivitet, hybridvektorer omfattende silke rekombinante DNA- molekyler, transformerte verster som passer for multlpliserlng og/eller ekspresjon av de remombinante DNA-molekylene, og foremgangmsåter for foremstilllng av proteinene, DNA-molekylene og vertene.
NO952039A 1992-11-27 1995-05-23 Proteiner med glykosyltransferase-aktivitet NO952039L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92810924 1992-11-27
PCT/EP1993/003194 WO1994012646A1 (en) 1992-11-27 1993-11-15 Proteins having glycosyltransferase activity

Publications (2)

Publication Number Publication Date
NO952039D0 NO952039D0 (no) 1995-05-23
NO952039L true NO952039L (no) 1995-05-23

Family

ID=8212036

Family Applications (1)

Application Number Title Priority Date Filing Date
NO952039A NO952039L (no) 1992-11-27 1995-05-23 Proteiner med glykosyltransferase-aktivitet

Country Status (11)

Country Link
US (1) US5641668A (no)
EP (1) EP0788548A1 (no)
JP (1) JPH08503373A (no)
KR (1) KR950704497A (no)
AU (1) AU682837B2 (no)
CA (1) CA2148929A1 (no)
FI (1) FI952574A0 (no)
MX (1) MX9307465A (no)
NO (1) NO952039L (no)
NZ (1) NZ258525A (no)
WO (1) WO1994012646A1 (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770420A (en) * 1995-09-08 1998-06-23 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures
EP0874900B1 (en) * 1996-08-02 2007-10-03 The Austin Research Institute Improved nucleic acids encoding a chimeric glycosyltransferase
US5945314A (en) * 1997-03-31 1999-08-31 Abbott Laboratories Process for synthesizing oligosaccharides
AU759792B2 (en) 1998-03-25 2003-05-01 Forschungszentrum Borstel Processive glycosyltransferase
US6586175B1 (en) * 1998-07-28 2003-07-01 Dna Sciences Laboratories, Inc. Genotyping the human UDP-glucuronosyltransferase 2B7 (UGT2B7) gene
ES2558160T3 (es) 1998-12-09 2016-02-02 Phyton Holdings, Llc Glicoproteínas que tienen glicosilación de tipo humano
TR200201121T2 (tr) 1999-10-26 2003-01-21 Plant Research International B.V. Bitkilerde memeli-tipi glikosilasyon
MXPA03006426A (es) 2001-01-19 2003-09-22 Dow Chemical Co Metodo para produccion secretoria de glicoproteina que tiene cadena de azucar humana, utilizando celula de planta.
IL161251A0 (en) 2001-10-10 2004-09-27 Neose Technologies Inc Remodeling and glycoconjugation of peptides
DK2279753T3 (en) 2001-10-10 2015-11-23 Novo Nordisk As The conversion of peptides and glycokonjugering
AU2002352253A1 (en) * 2001-12-18 2003-06-30 Bayer Healthcare Ag Regulation of human sialyltransferase
AU2003219402B2 (en) 2002-03-19 2008-05-08 Stichting Dienst Landbouwkundig Onderzoek GnTIII (UDP-n-acethylglucosamine:beta-D mannoside beta (1,4)-N-acethylglucosaminy ltransferase III) expression in plants
JP4532118B2 (ja) * 2002-03-19 2010-08-25 スティヒティング ディーンスト ランドバウクンディフ オンデルズーク 植物体内のグリカンプロセシングの最適化
EP1504023A4 (en) * 2002-05-03 2006-03-22 Neose Technologies Inc RECOMBINANT GLYCOSYL TRANSFERASE FUSION PROTEINS
NZ538439A (en) 2002-07-23 2007-02-23 Neose Technologies Inc Synthesis of oligosaccharides, glycolipids, and glycoproteins using bacterial glycosyltransferases
AR042145A1 (es) 2002-11-27 2005-06-08 Dow Agrociences Llc Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
MXPA05010773A (es) 2003-04-09 2005-12-12 Neose Technologies Inc Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos.
EP2484759B1 (en) 2004-02-04 2014-06-25 ratiopharm GmbH Methods of refolding mammalian glycosyltransferases
US8829276B2 (en) 2007-04-17 2014-09-09 Stichting Dienst Landbouwkundig Onderzoek Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
EP2824176A1 (en) * 2013-07-11 2015-01-14 Siamed'xpress Methods for producing sialylated therapeutic proteins
US10513724B2 (en) 2014-07-21 2019-12-24 Glykos Finland Oy Production of glycoproteins with mammalian-like N-glycans in filamentous fungi
CN107429237B (zh) * 2014-12-22 2021-09-28 豪夫迈·罗氏有限公司 Cmp依赖性的唾液酸酶活性
CA2971791A1 (en) * 2014-12-22 2016-06-30 Veterinaerinstituttet Salmon gill poxvirus
IN201611011974A (no) 2016-04-05 2018-02-02

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4751990A (en) * 1988-12-13 1990-07-10 La Jolla Cancer Research Foundation Nucleotides encoding human b1, 4-galactosyltransferase and uses thereof
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
US5541083A (en) * 1989-10-24 1996-07-30 The Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
CA2075949A1 (en) * 1990-02-14 1991-08-15 John B. Lowe Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules
WO1991016900A1 (en) * 1990-04-27 1991-11-14 Biogen, Inc. Fucosyl transferases involved in adhesion molecule expression
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen
GB2249096A (en) * 1990-10-11 1992-04-29 Ciba Geigy Saccharomyces cerevisiae strains lacking carboxypeptidase yscY activity for expression of proteins at high yields
US5461143A (en) * 1991-03-18 1995-10-24 The Scripps Research Institute Oligosaccharide enzyme substrates and inhibitors: methods and compositions

Also Published As

Publication number Publication date
CA2148929A1 (en) 1994-06-09
WO1994012646A1 (en) 1994-06-09
AU682837B2 (en) 1997-10-23
NO952039D0 (no) 1995-05-23
FI952574A (fi) 1995-05-26
US5641668A (en) 1997-06-24
NZ258525A (en) 1997-05-26
JPH08503373A (ja) 1996-04-16
AU5624294A (en) 1994-06-22
FI952574A0 (fi) 1995-05-26
EP0788548A1 (en) 1997-08-13
KR950704497A (ko) 1995-11-20
MX9307465A (es) 1994-08-31

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