DK41590A - Forbedrede protein c-molekyler samt fremgangsmaade til fremstilling og aktivering af samme - Google Patents
Forbedrede protein c-molekyler samt fremgangsmaade til fremstilling og aktivering af samme Download PDFInfo
- Publication number
- DK41590A DK41590A DK041590A DK41590A DK41590A DK 41590 A DK41590 A DK 41590A DK 041590 A DK041590 A DK 041590A DK 41590 A DK41590 A DK 41590A DK 41590 A DK41590 A DK 41590A
- Authority
- DK
- Denmark
- Prior art keywords
- molecules
- activation
- procedures
- preparation
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6464—Protein C (3.4.21.69)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20041—Use of virus, viral particle or viral elements as a vector
- C12N2710/20043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5136687A | 1987-05-18 | 1987-05-18 | |
PCT/US1988/002083 WO1989012685A1 (en) | 1987-05-18 | 1988-06-17 | Improved protein c molecules and method for making and activating same |
Publications (2)
Publication Number | Publication Date |
---|---|
DK41590D0 DK41590D0 (da) | 1990-02-16 |
DK41590A true DK41590A (da) | 1990-04-11 |
Family
ID=22208746
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK041590A DK41590A (da) | 1987-05-18 | 1990-02-16 | Forbedrede protein c-molekyler samt fremgangsmaade til fremstilling og aktivering af samme |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0380508A4 (da) |
JP (1) | JPH03501921A (da) |
DK (1) | DK41590A (da) |
WO (1) | WO1989012685A1 (da) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL95585A0 (en) * | 1989-09-05 | 1991-06-30 | Lilly Co Eli | Method for activating protein c |
ES2113878T3 (es) * | 1989-12-29 | 1998-05-16 | Zymogenetics Inc | Proteina c hibrida. |
US5358932A (en) * | 1989-12-29 | 1994-10-25 | Zymogenetics, Inc. | Hybrid protein C |
ES2052368T3 (es) * | 1990-01-26 | 1994-07-01 | Immuno Ag | Factores sanguineos producidos por recombinacion y el proceso para la expresion de dichos factores, asi como recombinacion del virus de vaccina usados en dicho proceso. |
JP3043558B2 (ja) * | 1993-10-29 | 2000-05-22 | 財団法人化学及血清療法研究所 | ヒト活性化プロテインc調製物及びその製法 |
WO2004113385A1 (en) * | 2003-06-20 | 2004-12-29 | Maxygen Holdings Ltd. | Protein c propeptide variants |
EP2336360A1 (en) | 2003-09-23 | 2011-06-22 | University Of North Carolina At Chapel Hill | Methods and compositions for the correlation of single nucleotide polymorphisms in the vitamin K epoxide reductase gene and warfarin dosage |
GB0324044D0 (en) | 2003-10-14 | 2003-11-19 | Astrazeneca Ab | Protein |
US20090325226A1 (en) | 2005-03-15 | 2009-12-31 | Stafford Darrel W | Methods and Compositions for Producing Active Vitamin K-Dependent Proteins |
NZ561925A (en) | 2005-04-13 | 2010-04-30 | Astrazeneca Ab | A host cell comprising a vector for production of proteins requiring gamma-carboxylation |
US8206967B2 (en) | 2007-07-06 | 2012-06-26 | Medimmune Limited | Method for production of recombinant human thrombin |
US9631002B2 (en) | 2010-12-21 | 2017-04-25 | The University Of North Carolina At Chapel Hill | Methods and compositions for producing active vitamin K-dependent proteins |
WO2014005183A1 (en) | 2012-07-04 | 2014-01-09 | The University Of Sydney | Treatment of inflammatory skin disorders |
DK3137102T3 (da) | 2014-04-16 | 2021-10-11 | Zz Biotech Llc | Apc til anvendelse til behandling af unormal kutan ardannelse |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4189534A (en) * | 1976-11-11 | 1980-02-19 | Massachusetts Institute Of Technology | Cell culture microcarriers |
US4579821A (en) * | 1981-11-23 | 1986-04-01 | University Patents, Inc. | Control of DNA sequence transcription |
US4775624A (en) * | 1985-02-08 | 1988-10-04 | Eli Lilly And Company | Vectors and compounds for expression of human protein C |
GR860984B (en) * | 1985-04-17 | 1986-08-18 | Zymogenetics Inc | Expression of factor vii and ix activities in mammalian cells |
US4751084A (en) * | 1986-02-26 | 1988-06-14 | Monsanto Company | Tissue plasminogen activator from normal human colon cells |
EP0245949B1 (en) * | 1986-04-09 | 1997-10-29 | Eli Lilly And Company | A method of using eukaryotic expression vectors comprising the bk virus enhancer |
IL82648A0 (en) * | 1986-05-27 | 1987-11-30 | Lilly Co Eli | Human protein s,a plasma protein regulator of hemostasis |
ZA889497B (en) * | 1987-12-28 | 1990-08-29 | Lilly Co Eli | Vectors and compounds for expression of zymogen forms of human protein c |
-
1988
- 1988-06-17 JP JP63506813A patent/JPH03501921A/ja active Pending
- 1988-06-17 WO PCT/US1988/002083 patent/WO1989012685A1/en not_active Application Discontinuation
- 1988-06-17 EP EP19880907471 patent/EP0380508A4/en not_active Withdrawn
-
1990
- 1990-02-16 DK DK041590A patent/DK41590A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0380508A1 (en) | 1990-08-08 |
WO1989012685A1 (en) | 1989-12-28 |
EP0380508A4 (en) | 1991-04-03 |
DK41590D0 (da) | 1990-02-16 |
JPH03501921A (ja) | 1991-05-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |