MX9307257A - Dimetilbenzofuranos y dimetilbenzopiranos como antagonistas de 5-ht3. - Google Patents
Dimetilbenzofuranos y dimetilbenzopiranos como antagonistas de 5-ht3.Info
- Publication number
- MX9307257A MX9307257A MX9307257A MX9307257A MX9307257A MX 9307257 A MX9307257 A MX 9307257A MX 9307257 A MX9307257 A MX 9307257A MX 9307257 A MX9307257 A MX 9307257A MX 9307257 A MX9307257 A MX 9307257A
- Authority
- MX
- Mexico
- Prior art keywords
- chch
- formula
- represents hydrogen
- novel compounds
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Addiction (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97901392A | 1992-11-20 | 1992-11-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9307257A true MX9307257A (es) | 1994-05-31 |
Family
ID=25526607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9307257A MX9307257A (es) | 1992-11-20 | 1993-11-19 | Dimetilbenzofuranos y dimetilbenzopiranos como antagonistas de 5-ht3. |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US5674868A (OSRAM) |
| EP (1) | EP0669919B1 (OSRAM) |
| JP (1) | JP2830952B2 (OSRAM) |
| KR (1) | KR0166661B1 (OSRAM) |
| AT (1) | ATE176232T1 (OSRAM) |
| AU (1) | AU680640B2 (OSRAM) |
| BG (1) | BG62489B1 (OSRAM) |
| BR (1) | BR9307477A (OSRAM) |
| CA (1) | CA2149044C (OSRAM) |
| CZ (1) | CZ287262B6 (OSRAM) |
| DE (1) | DE69323322T2 (OSRAM) |
| DK (1) | DK0669919T3 (OSRAM) |
| ES (1) | ES2129615T3 (OSRAM) |
| FI (1) | FI952458A7 (OSRAM) |
| GR (1) | GR3029831T3 (OSRAM) |
| HU (2) | HUT72740A (OSRAM) |
| IL (3) | IL119273A0 (OSRAM) |
| LV (1) | LV10956B (OSRAM) |
| MX (1) | MX9307257A (OSRAM) |
| NO (2) | NO307690B1 (OSRAM) |
| NZ (1) | NZ257854A (OSRAM) |
| OA (1) | OA10158A (OSRAM) |
| PL (1) | PL176051B1 (OSRAM) |
| RO (1) | RO115160B1 (OSRAM) |
| RU (1) | RU2116072C1 (OSRAM) |
| SG (1) | SG47488A1 (OSRAM) |
| SK (1) | SK282378B6 (OSRAM) |
| TW (1) | TW294595B (OSRAM) |
| UA (1) | UA49792C2 (OSRAM) |
| WO (1) | WO1994012494A1 (OSRAM) |
| ZA (1) | ZA938676B (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5374637A (en) * | 1989-03-22 | 1994-12-20 | Janssen Pharmaceutica N.V. | N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives |
| PT975327E (pt) * | 1997-04-18 | 2003-11-28 | Janssen Pharmaceutica Nv | Uso de antagonistas de 5ht3 para estimular a lavagem intestinal |
| WO1999002496A1 (en) * | 1997-07-11 | 1999-01-21 | Janssen Pharmaceutica N.V. | (+)-norcisapride useful for 5-ht3 and 5-ht4 mediated disorders |
| US6239122B1 (en) * | 2000-01-05 | 2001-05-29 | Joy Ann Steele | Method of treatment of nausea, vomiting, and other disorders using estrogens |
| ATE440825T1 (de) * | 2003-06-06 | 2009-09-15 | Vertex Pharma | Pyrimidin-derivate zur verwendung als modulatoren von atp-bindende kassette transportern |
| MXPA06005687A (es) | 2003-11-20 | 2006-08-17 | Janssen Pharmaceutica Nv | 2-quinolinonas y 2-quinoxalinonas sustituidas con 6-alquenilo y 6-fenilalquilo como inhibidores de la poli(adenosin fosfato-ribosa)polimerasa. |
| EA011211B1 (ru) | 2003-11-20 | 2009-02-27 | Янссен Фармацевтика Н. В. | 7-фенилалкилзамещённые 2-хинолиноны и 2-хиноксалиноны в качестве ингибиторов поли(адф-рибоза)полимеразы |
| AU2005259189B2 (en) | 2004-06-30 | 2011-04-21 | Janssen Pharmaceutica N.V. | Phthalazine derivatives as PARP inhibitors |
| AU2005259192C1 (en) * | 2004-06-30 | 2012-03-01 | Janssen Pharmaceutica N.V. | Substituted 2-alkyl quinazolinone derivatives as PARP inhibitors |
| SG154432A1 (en) | 2004-06-30 | 2009-08-28 | Janssen Pharmaceutica Nv | Quinazolinedione derivatives as parp inhibitors |
| WO2008107478A1 (en) | 2007-03-08 | 2008-09-12 | Janssen Pharmaceutica Nv | Quinolinone derivatives as parp and tank inhibitors |
| ES2448870T3 (es) | 2007-10-26 | 2014-03-17 | Janssen Pharmaceutica, N.V. | Derivados de quinolina como inhibidores de PARP |
| JP5492183B2 (ja) | 2008-03-27 | 2014-05-14 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Ｐａｒｐおよびチューブリン重合阻害剤としてのテトラヒドロフェナントリジノンおよびテトラヒドロシクロペンタキノリノン |
| EP2260026B1 (en) | 2008-03-27 | 2011-06-22 | Janssen Pharmaceutica, N.V. | Quinazolinone derivatives as tubulin polymerization inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1183847A (en) * | 1981-10-01 | 1985-03-12 | Georges Van Daele | N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
| ZW12187A1 (en) * | 1986-07-03 | 1989-02-01 | Janssen Pharmaceutica Nv | 4-(aroylamino)piperidinebutanamide derivatives |
| CA1317940C (en) * | 1987-09-25 | 1993-05-18 | Georges H. P. Van Daele | Substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides |
| US5374637A (en) * | 1989-03-22 | 1994-12-20 | Janssen Pharmaceutica N.V. | N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives |
| US4914207A (en) * | 1989-05-09 | 1990-04-03 | Pfizer Inc. | Arylthiazolylimidazoles |
| GB9005014D0 (en) * | 1990-03-06 | 1990-05-02 | Janssen Pharmaceutica Nv | N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives |
-
1993
- 1993-11-03 TW TW082109153A patent/TW294595B/zh active
- 1993-11-15 KR KR1019950701615A patent/KR0166661B1/ko not_active Expired - Fee Related
- 1993-11-15 AU AU54659/94A patent/AU680640B2/en not_active Ceased
- 1993-11-15 EP EP94900151A patent/EP0669919B1/en not_active Expired - Lifetime
- 1993-11-15 RU RU95113434A patent/RU2116072C1/ru not_active IP Right Cessation
- 1993-11-15 DE DE69323322T patent/DE69323322T2/de not_active Expired - Fee Related
- 1993-11-15 SG SG1996002238A patent/SG47488A1/en unknown
- 1993-11-15 US US08/416,914 patent/US5674868A/en not_active Expired - Fee Related
- 1993-11-15 HU HU9501476A patent/HUT72740A/hu unknown
- 1993-11-15 RO RO95-00941A patent/RO115160B1/ro unknown
- 1993-11-15 UA UA95048357A patent/UA49792C2/uk unknown
- 1993-11-15 CZ CZ19951258A patent/CZ287262B6/cs not_active IP Right Cessation
- 1993-11-15 CA CA002149044A patent/CA2149044C/en not_active Expired - Fee Related
- 1993-11-15 JP JP6512708A patent/JP2830952B2/ja not_active Expired - Fee Related
- 1993-11-15 AT AT94900151T patent/ATE176232T1/de not_active IP Right Cessation
- 1993-11-15 NZ NZ257854A patent/NZ257854A/en unknown
- 1993-11-15 PL PL93309045A patent/PL176051B1/pl not_active IP Right Cessation
- 1993-11-15 ES ES94900151T patent/ES2129615T3/es not_active Expired - Lifetime
- 1993-11-15 SK SK675-95A patent/SK282378B6/sk unknown
- 1993-11-15 BR BR9307477A patent/BR9307477A/pt not_active Application Discontinuation
- 1993-11-15 FI FI952458A patent/FI952458A7/fi unknown
- 1993-11-15 DK DK94900151T patent/DK0669919T3/da active
- 1993-11-15 WO PCT/EP1993/003206 patent/WO1994012494A1/en not_active Ceased
- 1993-11-18 IL IL11927396A patent/IL119273A0/xx unknown
- 1993-11-18 IL IL107654A patent/IL107654A/en not_active IP Right Cessation
- 1993-11-18 IL IL11927393A patent/IL119273A/xx not_active IP Right Cessation
- 1993-11-19 ZA ZA938676A patent/ZA938676B/xx unknown
- 1993-11-19 MX MX9307257A patent/MX9307257A/es unknown
-
1995
- 1995-04-20 BG BG99593A patent/BG62489B1/bg unknown
- 1995-05-19 NO NO951980A patent/NO307690B1/no unknown
- 1995-05-19 OA OA60663A patent/OA10158A/en unknown
- 1995-06-20 LV LVP-95-184A patent/LV10956B/en unknown
- 1995-06-30 HU HU95P/P00699P patent/HU211546A9/hu unknown
-
1997
- 1997-05-01 US US08/848,777 patent/US5863923A/en not_active Expired - Fee Related
-
1999
- 1999-03-31 GR GR990400922T patent/GR3029831T3/el unknown
- 1999-11-24 NO NO995762A patent/NO308530B1/no unknown
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