MX9306988A - Antagonistas de bradicinina y composicion farmaceutica que los comprende. - Google Patents

Antagonistas de bradicinina y composicion farmaceutica que los comprende.

Info

Publication number
MX9306988A
MX9306988A MX9306988A MX9306988A MX9306988A MX 9306988 A MX9306988 A MX 9306988A MX 9306988 A MX9306988 A MX 9306988A MX 9306988 A MX9306988 A MX 9306988A MX 9306988 A MX9306988 A MX 9306988A
Authority
MX
Mexico
Prior art keywords
bradicinine
antagonists
understand
pharmaceutical composition
bkan
Prior art date
Application number
MX9306988A
Other languages
English (en)
Inventor
John C Cheronis
James K Blodgett
Val Smith Goodfellow
Manoj V Marathe
Lyle W Spruce
Eric T Whalley
Original Assignee
Cortech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortech Inc filed Critical Cortech Inc
Publication of MX9306988A publication Critical patent/MX9306988A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se proporciona un antagonista de bradicinina de la fórmula: (BKAn) (X) (Y)donde BKAn es un péptido antagonista de la bradicinina, Y es unfarmacóforo; y X es un enlace de puente unido químicamente a loscomponentes BKAn e Y.
MX9306988A 1992-11-10 1993-11-09 Antagonistas de bradicinina y composicion farmaceutica que los comprende. MX9306988A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US97400092A 1992-11-10 1992-11-10

Publications (1)

Publication Number Publication Date
MX9306988A true MX9306988A (es) 1995-01-31

Family

ID=25521455

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9306988A MX9306988A (es) 1992-11-10 1993-11-09 Antagonistas de bradicinina y composicion farmaceutica que los comprende.

Country Status (11)

Country Link
EP (1) EP0671941A4 (es)
JP (1) JPH08503460A (es)
CN (1) CN1094058A (es)
AU (1) AU5410994A (es)
CA (1) CA2147869A1 (es)
IL (1) IL107400A0 (es)
MX (1) MX9306988A (es)
NZ (1) NZ257477A (es)
PL (1) PL304654A1 (es)
WO (1) WO1994011021A1 (es)
ZA (1) ZA938014B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ268969A (en) * 1993-07-23 1997-06-24 Toray Industries Morphinan derivatives and pharmaceutical compositions
AU6044496A (en) * 1995-06-05 1996-12-24 Cortech, Inc. Compounds having bradykinin antagonistic activity and mu-opi oid agonistic activity
AU703256B2 (en) * 1995-06-09 1999-03-25 Regents Of The University Of Michigan, The Bradykinin analogs as selective thrombin inhibitors
FR2739553B1 (fr) 1995-10-06 1998-01-02 Oreal Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
DE19612067A1 (de) * 1996-03-27 1997-10-02 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen
DE19642289A1 (de) 1996-10-14 1998-04-16 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung und Prävention der Alzheimer'schen Krankheit
US6982249B1 (en) 1997-04-23 2006-01-03 The Regents Of The University Of Michigan Bradykinin analogs as selective inhibitors of cell activation
US6359111B1 (en) * 1998-05-28 2002-03-19 Neorx Corporation Opioid receptor targeting
US7060708B2 (en) 1999-03-10 2006-06-13 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
US6716452B1 (en) 2000-08-22 2004-04-06 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
WO2003020200A2 (en) 2000-11-16 2003-03-13 New River Pharmaceuticals Inc. A novel pharmaceutical compound and methods of making and using same
EP2080511A3 (en) * 2000-08-22 2009-09-30 Shire LLC Active agent delivery systems and methods for protecting and administering active agents
ES2373641T3 (es) * 2000-11-16 2012-02-07 Shire Llc Un nuevo compuesto farmacéutico y métodos para fabricarlo y usarlo.
AU2001297565B2 (en) * 2000-11-16 2008-06-05 Takeda Pharmaceutical Company Limited A novel pharmaceutical compound and methods of making and using same
US7375082B2 (en) 2002-02-22 2008-05-20 Shire Llc Abuse-resistant hydrocodone compounds
US7338939B2 (en) 2003-09-30 2008-03-04 New River Pharmaceuticals Inc. Abuse-resistant hydrocodone compounds
US7169752B2 (en) 2003-09-30 2007-01-30 New River Pharmaceuticals Inc. Compounds and compositions for prevention of overdose of oxycodone
EP1531844B1 (en) 2002-02-22 2014-08-20 Shire LLC Novel sustained release pharmaceutical compounds to prevent abuse of controlled substances
US7700561B2 (en) 2002-02-22 2010-04-20 Shire Llc Abuse-resistant amphetamine prodrugs
EP1524979A2 (en) * 2002-07-31 2005-04-27 Schering AG New effector conjugates, process for their production and their pharmaceutical use
AR040956A1 (es) 2002-07-31 2005-04-27 Schering Ag Nuevos conjugados de efectores, procedimientos para su preparacion y su uso farmaceutico
CA2540678C (en) 2003-09-30 2011-02-22 New River Pharmaceuticals Inc. Pharmaceutical compositions for prevention of overdose or abuse
GB0624880D0 (en) * 2006-12-14 2007-01-24 Johnson Matthey Plc Improved method for making analgesics

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894443A (en) * 1984-02-08 1990-01-16 Cetus Corporation Toxin conjugates
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
EP0586613A4 (en) * 1991-04-01 1994-08-24 Cortech Inc Bradykinin antagonists
SE9101472D0 (sv) * 1991-05-15 1991-05-15 Trion Forskning & Utveckling Galanin antagonist

Also Published As

Publication number Publication date
CA2147869A1 (en) 1994-05-26
PL304654A1 (en) 1995-01-09
ZA938014B (en) 1994-07-11
NZ257477A (en) 1996-07-26
IL107400A0 (en) 1994-01-25
AU5410994A (en) 1994-06-08
CN1094058A (zh) 1994-10-26
EP0671941A1 (en) 1995-09-20
WO1994011021A1 (en) 1994-05-26
JPH08503460A (ja) 1996-04-16
EP0671941A4 (en) 1996-05-29

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