DE68925923D1 - Antigene der einzigen Spaltungsstelle von Fibrinogen durch Elastase - Google Patents

Antigene der einzigen Spaltungsstelle von Fibrinogen durch Elastase

Info

Publication number
DE68925923D1
DE68925923D1 DE68925923T DE68925923T DE68925923D1 DE 68925923 D1 DE68925923 D1 DE 68925923D1 DE 68925923 T DE68925923 T DE 68925923T DE 68925923 T DE68925923 T DE 68925923T DE 68925923 D1 DE68925923 D1 DE 68925923D1
Authority
DE
Germany
Prior art keywords
elastase
antigens
cleavage site
fibrinogen cleavage
fibrinogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68925923T
Other languages
English (en)
Other versions
DE68925923T2 (de
Inventor
Mary E Dahlgren
Richard A Mumford
Joshua S Boger
D T Philip Davies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE68925923D1 publication Critical patent/DE68925923D1/de
Application granted granted Critical
Publication of DE68925923T2 publication Critical patent/DE68925923T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/75—Fibrin; Fibrinogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE1989625923 1988-06-10 1989-06-07 Antigene der einzigen Spaltungsstelle von Fibrinogen durch Elastase Expired - Lifetime DE68925923T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20541688A 1988-06-10 1988-06-10
US20541888A 1988-06-10 1988-06-10
US20541788A 1988-06-10 1988-06-10

Publications (2)

Publication Number Publication Date
DE68925923D1 true DE68925923D1 (de) 1996-04-18
DE68925923T2 DE68925923T2 (de) 1996-11-14

Family

ID=27394787

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1989625923 Expired - Lifetime DE68925923T2 (de) 1988-06-10 1989-06-07 Antigene der einzigen Spaltungsstelle von Fibrinogen durch Elastase

Country Status (3)

Country Link
EP (1) EP0345906B1 (de)
JP (1) JPH02117699A (de)
DE (1) DE68925923T2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6124107A (en) * 1988-06-10 2000-09-26 Merck & Co., Inc. Assay for marker of human polymorphonuclear leukocyte elastase activity
FR2660757B1 (fr) * 1990-04-06 1994-05-27 Immunotech Sa Procede d'identification ou de dosage de proteines et applications.
IE911697A1 (en) * 1990-05-24 1991-12-04 Zeneca Ltd Therapeutic agent
DK0458537T3 (da) * 1990-05-24 1999-10-18 Zeneca Ltd Anvendelse af en terapeutisk forbindelse til behandling af bronkitis
US5162348A (en) * 1990-05-24 1992-11-10 Imperial Chemical Industries Plc Treatment of cystic fibrosis
IT1243281B (it) * 1990-06-12 1994-05-26 Fidia Spa Metodo per la determinazione quantitativa e qualitativa di polipeptidiin liquidi proteici
IE912528A1 (en) * 1990-07-19 1992-01-29 Scripps Clinic Res Inhabition of mac-1 receptor binding fibrinogen using d30¹homologs
JP3889084B2 (ja) * 1996-05-15 2007-03-07 株式会社三菱化学ヤトロン 新規なモノクローナル抗体並びにｅ−Ｄダイマー及びｅ−ＤＤ／Ｅ複合体の免疫学的測定法
US20050118598A1 (en) * 2002-02-19 2005-06-02 Carlos Garcia-Echeverria Organic compounds
JP4608630B2 (ja) 2005-02-21 2011-01-12 独立行政法人産業技術総合研究所 イオン発生器及び除電器
JP2007242568A (ja) * 2006-03-13 2007-09-20 Trinc:Kk 除電器

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8701437L (sv) * 1987-04-06 1988-10-07 Rolf Kenth Sigvard Wallin Diagnostiskt foerfarande in vitro samt medel som kan utnyttjas vid foerfarandet

Also Published As

Publication number Publication date
EP0345906B1 (de) 1996-03-13
EP0345906A3 (en) 1990-11-22
JPH02117699A (ja) 1990-05-02
EP0345906A2 (de) 1989-12-13
DE68925923T2 (de) 1996-11-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition