MX9303972A - Procedimiento para hacer compuestos de tioeter. - Google Patents

Procedimiento para hacer compuestos de tioeter.

Info

Publication number
MX9303972A
MX9303972A MX9303972A MX9303972A MX9303972A MX 9303972 A MX9303972 A MX 9303972A MX 9303972 A MX9303972 A MX 9303972A MX 9303972 A MX9303972 A MX 9303972A MX 9303972 A MX9303972 A MX 9303972A
Authority
MX
Mexico
Prior art keywords
compounds
making
thioeter
procedure
thiolphenol
Prior art date
Application number
MX9303972A
Other languages
English (en)
Inventor
Robert A Daines
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of MX9303972A publication Critical patent/MX9303972A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Esta invención se refiere a un procedimiento para hacer un compuesto de la fórmula I en donde los varios grupos son definidos en la presente, dicho procedimiento comprende la copulación de un tiolfenol o fenilalquimercaptano en presencia de 1,8-diazabiciclo[5.4.0]undec-7-eno (DBU) bajo una atmósfera inerte. Estos compuestos son antagonistas de leucotrieno y como tales pueden ser utilizados en el tratamiento de varias enfermedades asociadas con leucotrienos.
MX9303972A 1992-06-30 1993-06-30 Procedimiento para hacer compuestos de tioeter. MX9303972A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90695192A 1992-06-30 1992-06-30
US2520093A 1993-03-02 1993-03-02

Publications (1)

Publication Number Publication Date
MX9303972A true MX9303972A (es) 1994-04-29

Family

ID=26699426

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9303972A MX9303972A (es) 1992-06-30 1993-06-30 Procedimiento para hacer compuestos de tioeter.

Country Status (10)

Country Link
EP (1) EP0649408A4 (es)
JP (1) JP3181917B2 (es)
KR (1) KR950702184A (es)
CN (1) CN1095713A (es)
AU (1) AU678979B2 (es)
CA (1) CA2138955A1 (es)
MX (1) MX9303972A (es)
NZ (1) NZ254473A (es)
TW (1) TW247907B (es)
WO (1) WO1994000433A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09506367A (ja) * 1993-12-08 1997-06-24 スミスクライン・ビーチャム・コーポレイション 化合物
GB9508137D0 (en) * 1995-04-21 1995-06-07 Smithkline Beecham Plc Formulation
CN1314666C (zh) * 2005-12-19 2007-05-09 华中师范大学 微波辅助合成硫醚类化合物的方法
KR200481393Y1 (ko) * 2014-08-06 2016-09-27 김상열 스마트 슬림 스탠드

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3810379A1 (de) * 1988-03-26 1989-10-12 Hoechst Ag Azaneophyl- und silazaneophylsulfide, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als schaedlingsbekaempfungsmittel
WO1991018601A1 (en) * 1990-06-07 1991-12-12 Smithkline Beecham Corporation Benzoic acid derivatives
CA2089728A1 (en) * 1990-09-13 1992-03-14 James S. Frazee Pyridylthio or pyridyloxy alkanoic acids
AU2573592A (en) * 1991-09-19 1993-04-27 Smithkline Beecham Corporation Pyridine compounds for treating leukotriene-related diseases

Also Published As

Publication number Publication date
JP3181917B2 (ja) 2001-07-03
EP0649408A4 (en) 1995-06-21
AU678979B2 (en) 1997-06-19
WO1994000433A1 (en) 1994-01-06
TW247907B (es) 1995-05-21
AU4655793A (en) 1994-01-24
CA2138955A1 (en) 1994-01-06
KR950702184A (ko) 1995-06-19
CN1095713A (zh) 1994-11-30
NZ254473A (en) 1996-11-26
EP0649408A1 (en) 1995-04-26
JPH07508283A (ja) 1995-09-14

Similar Documents

Publication Publication Date Title
PT75140B (en) Process for the preparation of detergent compositions containi ng carboxilic acid anphoteric-alcoxilated complexes
CO4290353A1 (es) Agonistas de estrogeno
IT1254915B (it) Derivati di adenosina ad attivita' a2 agonista
ATE197158T1 (de) Verbindungen mit wachstumshormonfreisetzenden eigenschaften
WO1996023489A3 (de) Verwendung von carotinoiden zur herstellung von arzneimitteln zur behandlung von dermatosen
DE69106586D1 (de) Verwendung von Baclofen zur Herstellung von Arzneimitteln zur Behandlung von Angina pectoris.
IT1252227B (it) Composti tetrametilpiperidinici atti all'impiego come stabilizzanti per materiali organici
ES2033912T3 (es) Procedimiento de preparacion de un organopolisiloxano con funcion acrilato y/o metacrilato.
JPS55108860A (en) Hydroxypropylltriazole*its manufacture and use as medicine
ES2084339T3 (es) Tetrahidropiridinas e hidroxipiperidinas sustituidas utiles como agentes para el sistema nervioso central.
DE69229339D1 (de) Kristallines tiagabinehydrochlorid-monohydrat, seine herstellung und verwendung
PT87618A (pt) Process for the preparation of polymeric hinderd amine light stabilizers and organic compositions therewith
EP0293751A3 (en) Taurohyodeoxycholic acid for the therapy of calculosis of the biliary tract and of biliary dyspepsia
ES2060818T3 (es) Derivados de indol, benzofurano y benzotiofeno sustituidos como inhibidores de la 5-lipooxigenasa.
MX9303972A (es) Procedimiento para hacer compuestos de tioeter.
JPS6490125A (en) Drug composition
DE69718469D1 (de) Verbindungen mit wachtumshormon freisetzenden eigenschaften
ES2067244T3 (es) Compuestos peptidicos que presentan una actividad de liberacion de la hormona del crecimiento.
CO4900019A1 (es) Composiciones para el cuidado oral antimicrobial y metodos para tratar enfermedades periodontales y el mal aliento
ATE174026T1 (de) Chromen-derivate mit einer trien-kette zur verwendung bei der behandlung der osteoporose und der entzündlichen erkrankungen
DK691288A (da) Cyclopropanderivater
DE3673037D1 (de) Herstellung von "gossyplure"und 1-metallo-5,9-tetradecadien.
MX9606494A (es) Compuestos organicos.
ES2062407T3 (es) Compuestos de 2-hidroxi-3-fenoxipropilamino.
SE8200515L (sv) Bicykliska foreningar