MX9204334A - Procedimiento para la preparacion de dimetil pipodo fillo toxina. - Google Patents

Procedimiento para la preparacion de dimetil pipodo fillo toxina.

Info

Publication number
MX9204334A
MX9204334A MX9204334A MX9204334A MX9204334A MX 9204334 A MX9204334 A MX 9204334A MX 9204334 A MX9204334 A MX 9204334A MX 9204334 A MX9204334 A MX 9204334A MX 9204334 A MX9204334 A MX 9204334A
Authority
MX
Mexico
Prior art keywords
pipodo
fillo
toxina
dimetil
procedure
Prior art date
Application number
MX9204334A
Other languages
English (en)
Inventor
Prieto Allevi
Mario Anastasia
Ettore Bigatti
Peter Mcdonald
Original Assignee
Sicor Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11360401&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9204334(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sicor Spa filed Critical Sicor Spa
Publication of MX9204334A publication Critical patent/MX9204334A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MX9204334A 1991-07-23 1992-07-23 Procedimiento para la preparacion de dimetil pipodo fillo toxina. MX9204334A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912025A IT1250692B (it) 1991-07-23 1991-07-23 Procedimento per la preparazione di demetilepipodofillotossina- beta-d-glucosidi.

Publications (1)

Publication Number Publication Date
MX9204334A true MX9204334A (es) 1993-02-01

Family

ID=11360401

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9204334A MX9204334A (es) 1991-07-23 1992-07-23 Procedimiento para la preparacion de dimetil pipodo fillo toxina.

Country Status (16)

Country Link
US (1) US5688925A (es)
EP (1) EP0595888B1 (es)
JP (1) JP3231765B2 (es)
AT (1) ATE159026T1 (es)
AU (1) AU666322B2 (es)
CA (1) CA2113894C (es)
DE (1) DE69222643T2 (es)
DK (1) DK0595888T3 (es)
ES (1) ES2107546T3 (es)
FI (1) FI110782B (es)
GR (1) GR3025729T3 (es)
IL (1) IL102610A (es)
IT (1) IT1250692B (es)
MX (1) MX9204334A (es)
WO (1) WO1993002094A1 (es)
ZA (1) ZA925515B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL119749A (en) * 1995-12-04 2001-03-19 Nippon Kayaku Kk Process for producing etoposide
KR100519498B1 (ko) * 1997-06-02 2005-10-07 브리스톨-마이어즈 스퀴브 컴페니 에토포사이드의 제조방법
AU5612399A (en) 1998-09-10 2000-04-03 Phytogen Life Sciences Inc. Synthetic method for the preparation of the antineoplastic agent etoposide
FR2791681B1 (fr) * 1999-03-29 2001-06-22 Pf Medicament Nouveau procede de preparation de l'etoposide
GB0019124D0 (en) * 2000-08-03 2000-09-27 Pfizer Novel process
CN101146532B (zh) 2005-01-21 2012-05-09 阿斯泰克斯治疗有限公司 药物化合物
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
EP4176871A1 (en) 2011-10-03 2023-05-10 Canqura Oncology Ab Nanoparticles, process for preparation and use thereof as carrier for amphipatic of hydrphobic molecules in fields of medicine including cancer treatment and food related compounds
AR095962A1 (es) 2013-04-01 2015-11-25 Moreinx Ab Nanopartículas, compuestas de esterol y saponina de quillaja saponaria molina, proceso para preparación y uso de las mismas como portadores para moléculas anfipáticas o hidrófobas en el campo de la medicina incluyendo tratamiento de cáncer y compuestos relacionados con alimentos
EP3616688A1 (en) 2018-08-27 2020-03-04 Centre National de la Recherche Scientifique - CNRS Preparation of nanosuspension comprising nanocrystals of active pharmaceutical ingredients with little or no stabilizing agents
EP3669890A1 (en) 2018-12-18 2020-06-24 Croda International PLC Filamentous nanoparticles having vaccine adjuvant effect
CN113121618A (zh) * 2021-04-07 2021-07-16 梯尔希（南京）药物研发有限公司 两种依托泊苷杂质的制备方法
CN115197281A (zh) * 2021-04-09 2022-10-18 四川汇宇制药股份有限公司 依托泊苷中间体的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0111058B1 (en) * 1982-11-26 1987-11-04 Nippon Kayaku Kabushiki Kaisha Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof
JPS60246393A (ja) * 1984-05-22 1985-12-06 Nippon Kayaku Co Ltd エトポシドの新規製造法
IL77334A (en) * 1985-12-16 1991-04-15 Univ Bar Ilan Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor
DK39886D0 (da) * 1986-01-27 1986-01-27 Hans Goeran Magnusson Hydroxybeskyttelsesgrupper
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
US4965348A (en) * 1989-05-19 1990-10-23 Bristol-Myers Company Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
DE3935016A1 (de) * 1989-10-20 1991-04-25 Behringwerke Ag Glycosyl-etoposid-prodrugs, verfahren zu ihrer herstellung und ihre anwendung in kombination mit funktionalisiertem tumorspezifischen enzym-konjugaten
FR2658824B1 (fr) * 1990-02-27 1992-07-03 Pf Medicament Tris acetyl-2",3",4' ethylidene-4",6" beta-d-glucopyranosides, leur preparation et leur utilisation pour la preparation d'ethylidene beta-d-glucopyranoside de demethyl-4' epipodophyllotoxine.
US5081234A (en) * 1990-04-30 1992-01-14 Bristol-Myers Squibb Co. 4'-demethylepipodophyllotoxin glycosides
CN1025918C (zh) * 1990-06-07 1994-09-14 国家医药管理局上海医药工业研究院 抗肿瘤药表鬼臼毒吡喃糖甙的合成新工艺

Also Published As

Publication number Publication date
ATE159026T1 (de) 1997-10-15
IL102610A (en) 1997-03-18
WO1993002094A1 (en) 1993-02-04
IT1250692B (it) 1995-04-21
GR3025729T3 (en) 1998-03-31
DE69222643D1 (de) 1997-11-13
JP3231765B2 (ja) 2001-11-26
AU666322B2 (en) 1996-02-08
FI940280A (fi) 1994-01-20
JPH06509334A (ja) 1994-10-20
CA2113894A1 (en) 1993-02-04
EP0595888A1 (en) 1994-05-11
DK0595888T3 (da) 1998-05-18
AU2326592A (en) 1993-02-23
CA2113894C (en) 2003-12-16
DE69222643T2 (de) 1998-02-05
FI110782B (fi) 2003-03-31
FI940280A0 (fi) 1994-01-20
ZA925515B (en) 1993-04-28
ITMI912025A1 (it) 1993-01-24
ITMI912025A0 (it) 1991-07-23
US5688925A (en) 1997-11-18
ES2107546T3 (es) 1997-12-01
EP0595888B1 (en) 1997-10-08

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