GB9122988D0
(en)
*
|
1991-10-30 |
1991-12-18 |
Ici Plc |
Heterocyclic compounds
|
GB9127279D0
(en)
*
|
1991-12-23 |
1992-02-19 |
Ici Plc |
Heterocyclic derivatives
|
GB9201749D0
(en)
*
|
1992-01-28 |
1992-03-11 |
Smithkline Beecham Plc |
Medicaments
|
US5726306A
(en)
*
|
1992-04-20 |
1998-03-10 |
Takeda Chemical Industries, Ltd. |
4,1-benzoxazepin derivatives and their use
|
EP0596058A1
(en)
*
|
1992-04-10 |
1994-05-11 |
Zeneca Limited |
Biphenylylquinuclidine derivatives as squalene synthase inhibitors
|
GB9207961D0
(en)
*
|
1992-04-10 |
1992-05-27 |
Ici Plc |
Heterocyclic derivatives
|
DE69332792T2
(de)
*
|
1992-04-20 |
2004-01-15 |
Takeda Chemical Industries Ltd |
4,1-Benzoxazepinderivate als Squalen-Synthetase Inhibitoren und ihre Verwendung zur Behandlung von Hypercholesterämie und als Fungizide
|
GB9211796D0
(en)
*
|
1992-06-04 |
1992-07-15 |
Ici Plc |
Heterocyclic derivatives
|
GB9216721D0
(en)
*
|
1992-08-06 |
1992-09-23 |
Ici Plc |
Therapeutic heterocyclic derivatives
|
GB9218334D0
(en)
*
|
1992-08-28 |
1992-10-14 |
Ici Plc |
Heterocyclic compounds
|
GB9226573D0
(en)
*
|
1992-12-21 |
1993-02-17 |
Ici Plc |
Heterocyclic compounds
|
WO1994014803A1
(en)
*
|
1992-12-21 |
1994-07-07 |
Zeneca Limited |
Quinuclidine derivatives as squalene synthase inhibitors
|
GB9226577D0
(en)
*
|
1992-12-21 |
1993-02-17 |
Ici Plc |
Heterocyclic derivatives
|
US5451596A
(en)
*
|
1992-12-29 |
1995-09-19 |
Rhone Poulenc Rorer Pharmaceuticals Inc. |
Cycloalkyl amine bis-aryl squalene synthase inhibitors
|
CA2115183A1
(en)
*
|
1993-02-12 |
1994-08-13 |
Takashi Nomoto |
Substituted amic acid derivatives
|
IL109451A0
(en)
*
|
1993-04-29 |
1994-07-31 |
Zeneca Ltd |
Heterocyclic derivatives
|
AU678503B2
(en)
*
|
1993-09-24 |
1997-05-29 |
Takeda Chemical Industries Ltd. |
Condensed heterocyclic compounds and their use as squalene synthetase inhibitors
|
GB9412145D0
(en)
*
|
1994-06-17 |
1994-08-10 |
Zeneca Ltd |
Heterocycles
|
US5556990A
(en)
*
|
1994-12-16 |
1996-09-17 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Polyarylcarbamoylaza- and -carbamoylalkanedioic acids
|
US6297198B1
(en)
|
1996-05-14 |
2001-10-02 |
Syngenta Participations Ag |
Isoxazole derivatives and their use as herbicides
|
SE9902987D0
(sv)
|
1999-08-24 |
1999-08-24 |
Astra Pharma Prod |
Novel compounds
|
KR100694687B1
(ko)
*
|
1999-09-28 |
2007-03-13 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
퀴누클리딘 화합물 및 그것을 유효성분으로서 함유하는 의약
|
WO2002016357A2
(en)
|
2000-08-18 |
2002-02-28 |
Pharmacia & Upjohn Company |
Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
|
WO2002016358A2
(en)
|
2000-08-18 |
2002-02-28 |
Pharmacia & Upjohn Company |
Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
|
US6492385B2
(en)
|
2000-08-18 |
2002-12-10 |
Pharmacia & Upjohn Company |
Quinuclidine-substituted heteroaryl moieties for treatment of disease
|
WO2002017358A2
(en)
|
2000-08-21 |
2002-02-28 |
Pharmacia & Upjohn Company |
Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic acetylcholine receptor antagonists)
|
US6599916B2
(en)
|
2000-08-21 |
2003-07-29 |
Pharmacia & Upjohn Company |
Quinuclidine-substituted heteroaryl moieties for treatment of disease
|
GB0104050D0
(en)
|
2001-02-19 |
2001-04-04 |
Astrazeneca Ab |
Chemical compounds
|
GB0107228D0
(en)
|
2001-03-22 |
2001-05-16 |
Astrazeneca Ab |
Chemical compounds
|
EP1375496B1
(en)
*
|
2001-03-27 |
2007-07-04 |
Eisai R&D Management Co., Ltd. |
N-aryl-substituted cyclic amine derivative and medicine containing the same as active ingredient
|
PE20021019A1
(es)
|
2001-04-19 |
2002-11-13 |
Upjohn Co |
Grupos azabiciclicos sustituidos
|
BR0212101A
(pt)
|
2001-08-24 |
2004-08-24 |
Pharmacia & Up John Company |
7-aza [2.2.1] biciclo-heptanos substituìdos com heteroarila para o tratamento de doenças
|
MXPA04004464A
(es)
|
2001-11-08 |
2004-08-11 |
Upjohn Co |
Compuestos de heteroarilo sustituido con azabiciclo para el tratamiento de enfermedades.
|
SE0103818D0
(sv)
|
2001-11-15 |
2001-11-15 |
Astrazeneca Ab |
Chemical compounds
|
BR0307714A
(pt)
|
2002-02-15 |
2005-02-09 |
Upjohn Co |
Benzoilamidas substituìdas com azabiciclo e tioamidas para tratamento de distúrbios relacionados ao cns
|
AU2003253686A1
(en)
|
2002-08-01 |
2004-02-23 |
Pharmacia & Upjohn Company Llc |
1h-pyrazole and 1h-pyrrole-azabicyclic compounds with alfa-7 nachr activity
|
GB0220581D0
(en)
|
2002-09-04 |
2002-10-09 |
Novartis Ag |
Organic Compound
|
SE0301369D0
(sv)
|
2003-05-09 |
2003-05-09 |
Astrazeneca Ab |
Chemical compounds
|
DE10334724A1
(de)
*
|
2003-07-30 |
2005-02-24 |
Bayer Healthcare Ag |
N-Biarylamide
|
EP1824848A1
(en)
*
|
2004-12-10 |
2007-08-29 |
Abbott Laboratories |
Fused bicycloheterocycle substituted quinuclidine derivatives
|
US7160876B2
(en)
*
|
2003-12-22 |
2007-01-09 |
Abbott Laboratories |
Fused bicycloheterocycle substituted quinuclidine derivatives
|
US20050245531A1
(en)
*
|
2003-12-22 |
2005-11-03 |
Abbott Laboratories |
Fused bicycloheterocycle substituted quinuclidine derivatives
|
US7655657B2
(en)
|
2003-12-22 |
2010-02-02 |
Abbott Laboratories |
Fused bicycloheterocycle substituted quinuclidine derivatives
|
PE20060437A1
(es)
|
2004-06-18 |
2006-06-08 |
Novartis Ag |
COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR
|
US7781478B2
(en)
|
2004-07-14 |
2010-08-24 |
Ptc Therapeutics, Inc. |
Methods for treating hepatitis C
|
GB0415746D0
(en)
|
2004-07-14 |
2004-08-18 |
Novartis Ag |
Organic compounds
|
GB0611907D0
(en)
|
2006-06-15 |
2006-07-26 |
Glaxo Group Ltd |
Compounds
|
AR052674A1
(es)
|
2005-02-17 |
2007-03-28 |
Wyeth Corp |
Derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilcondensados
|
GB0521508D0
(en)
|
2005-10-21 |
2005-11-30 |
Novartis Ag |
Organic compounds
|
GB0525672D0
(en)
|
2005-12-16 |
2006-01-25 |
Novartis Ag |
Organic compounds
|
GB0525673D0
(en)
|
2005-12-16 |
2006-01-25 |
Novartis Ag |
Organic compounds
|
US8314119B2
(en)
|
2006-11-06 |
2012-11-20 |
Abbvie Inc. |
Azaadamantane derivatives and methods of use
|
RU2579121C2
(ru)
|
2010-09-23 |
2016-03-27 |
Эббви Бахамаз Лтд. |
Моногидрат производного азаадамантана
|
WO2016021706A1
(ja)
*
|
2014-08-08 |
2016-02-11 |
カズマパートナーズ株式会社 |
縮合複素環化合物
|
EP3416962B1
(en)
|
2016-02-15 |
2021-05-05 |
Sanofi |
6,7-dihydro-5h-benzo[7]annulene derivatives as estrogen receptor modulators
|
AU2017362460B2
(en)
|
2016-11-17 |
2021-07-22 |
Sanofi |
Novel substituted N-(3-fluoropropyl)-pyrrolidine compounds, processes for their preparation and therapeutic uses thereof
|
EP3434272A1
(en)
|
2017-07-25 |
2019-01-30 |
Sanofi |
Combination comprising palbociclib and 6-(2,4-dichlorophenyl)-5-[4-[(3s)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7h-benzo[7]annulene-2-carboxylic acid
|
AU2019335542A1
(en)
|
2018-09-07 |
2021-04-01 |
Sanofi |
Process for the preparation of methyl 6-(2,4-dichlorophenyl)-5-(4-((3s)-1-(3-fluoropropyl)pyrrolidin-3-yl)oxyphenyl)-8,9-dihydro-7H-benzo(7)annulene-2-carboxylate
|