MX387128B - Métodos para la síntesis de esfingomielinas y dihidroesfingomielinas. - Google Patents
Métodos para la síntesis de esfingomielinas y dihidroesfingomielinas.Info
- Publication number
- MX387128B MX387128B MX2015012877A MX2015012877A MX387128B MX 387128 B MX387128 B MX 387128B MX 2015012877 A MX2015012877 A MX 2015012877A MX 2015012877 A MX2015012877 A MX 2015012877A MX 387128 B MX387128 B MX 387128B
- Authority
- MX
- Mexico
- Prior art keywords
- synthesis
- sphingomyelins
- methods
- dihydroesphingomyelins
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/141—Esters of phosphorous acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/24—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and acyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/10—Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/113—Esters of phosphoric acids with unsaturated acyclic alcohols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361801641P | 2013-03-15 | 2013-03-15 | |
| EP13306056 | 2013-07-23 | ||
| PCT/IB2014/000494 WO2014140787A2 (en) | 2013-03-15 | 2014-03-14 | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015012877A MX2015012877A (es) | 2016-02-03 |
| MX387128B true MX387128B (es) | 2025-03-19 |
Family
ID=51538203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015012877A MX387128B (es) | 2013-03-15 | 2014-03-14 | Métodos para la síntesis de esfingomielinas y dihidroesfingomielinas. |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US20140316154A1 (OSRAM) |
| EP (3) | EP3363805B1 (OSRAM) |
| JP (2) | JP6438417B2 (OSRAM) |
| KR (1) | KR20150132188A (OSRAM) |
| CN (1) | CN105051051B (OSRAM) |
| AU (2) | AU2014229638B2 (OSRAM) |
| BR (1) | BR112015023558A2 (OSRAM) |
| CA (1) | CA2900902C (OSRAM) |
| DK (1) | DK3363805T3 (OSRAM) |
| ES (1) | ES3017659T3 (OSRAM) |
| HK (1) | HK1214266A1 (OSRAM) |
| MX (1) | MX387128B (OSRAM) |
| PH (1) | PH12015501835B1 (OSRAM) |
| SG (2) | SG10201804887YA (OSRAM) |
| WO (1) | WO2014140787A2 (OSRAM) |
| ZA (1) | ZA201505860B (OSRAM) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT201700203T1 (it) | 2009-02-16 | 2017-05-08 | Cerenis Therapeutics Holding Sa | Mimetici di apolipoproteina a-i |
| SG2014012850A (en) | 2010-10-18 | 2014-05-29 | Cerenis Therapeutics Holding Sa | Compounds, compositions and methods useful for cholesterol mobilisation |
| JP6438417B2 (ja) * | 2013-03-15 | 2018-12-12 | セレニス セラピューティクス ホールディング エスアー | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
| US9708354B2 (en) | 2013-03-15 | 2017-07-18 | Cerenis Therapeutics Holding Sa | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
| WO2019030574A1 (en) | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding | Cargomers |
| WO2019030575A1 (en) | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding | APOMÈRES |
| EP3778611B1 (en) * | 2018-03-27 | 2022-10-12 | NOF Corporation | Sphingomyelin-derived lipid and method for producing same |
| JP7303618B2 (ja) * | 2018-10-05 | 2023-07-05 | 日本精化株式会社 | スフィンゴリン脂質前駆体及びその製造方法、並びに、スフィンゴリン脂質の製造方法 |
| WO2021209808A1 (en) | 2020-04-16 | 2021-10-21 | Abionyx Pharma Sa | Cer-001 therapy for treating kidney disease |
| IL297046A (en) | 2020-04-16 | 2022-12-01 | Abionyx Pharma Sa | Treatment of kidney disease using cer-001 |
| CN115427064A (zh) | 2020-04-16 | 2022-12-02 | 阿比奥尼克斯制药公司 | 使用基于脂质结合蛋白的复合物治疗急性病况的方法 |
| EP4221686A2 (en) | 2020-10-01 | 2023-08-09 | Abionyx Pharma SA | Compositions comprising lipid binding protein-based complexes for use for treating eye diseases |
| JP2024514154A (ja) | 2021-04-15 | 2024-03-28 | アビオニクス ファーマ エスエー | 臓器保存溶液における脂質結合タンパク質ベースの複合体の使用 |
| CA3247588A1 (en) | 2022-04-06 | 2023-10-12 | Abionyx Pharma Sa | METHODS FOR TREATING LEUKOCYTOSIS, ENDOTHELIAL DYSFUNCTION AND CARDITIS USING LIPID-BINDING PROTEIN COMPLEXES |
| AU2023250345A1 (en) | 2022-04-06 | 2024-11-14 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
| WO2023237927A2 (en) | 2022-06-10 | 2023-12-14 | Abionyx Pharma Sa | Methods for treating hyperinflammatory conditions using lipid binding protein -based complexes |
| AU2023284357A1 (en) | 2022-06-10 | 2025-01-23 | Abionyx Pharma Sa | Methods for treating acute conditions using lipid binding protein-based complexes |
| KR20250035547A (ko) | 2022-06-28 | 2025-03-12 | 아비오닉스 파마 에스에이 | 스핑고미엘린의 합성을 위한 화합물 및 공정 |
| IL322074A (en) | 2023-01-13 | 2025-09-01 | Abionyx Pharma Sa | Treatment using a lipid-binding protein molecule |
| WO2025093929A1 (en) | 2023-10-31 | 2025-05-08 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0146810A3 (de) | 1983-12-05 | 1987-05-13 | Solco Basel AG | Verfahren zur Herstellung von Sphingosinderivaten |
| US5220043A (en) * | 1991-03-21 | 1993-06-15 | Ohio University | Synthesis of D-erythro-sphingomyelins |
| CN1099868C (zh) | 1993-11-16 | 2003-01-29 | 斯卡法玛公司 | 具有控制释放活性成分作用的囊 |
| US5766627A (en) | 1993-11-16 | 1998-06-16 | Depotech | Multivescular liposomes with controlled release of encapsulated biologically active substances |
| CA2320117A1 (en) * | 1998-02-12 | 1999-08-19 | Emory University | Sphingolipid derivatives and their methods of use |
| JP2004002215A (ja) * | 2002-05-23 | 2004-01-08 | National Institute Of Advanced Industrial & Technology | スフィンゴ脂質誘導体の製造方法 |
| EP1704155A1 (en) | 2004-01-15 | 2006-09-27 | Biolab Ltd. | Sphingomyelin, intermediates thereof and methods for preparation of same |
| CA2566559C (en) | 2004-05-17 | 2014-05-06 | Inex Pharmaceuticals Corporation | Liposomal formulations comprising dihydrosphingomyelin and methods of use thereof |
| CA2572310A1 (en) * | 2004-06-29 | 2006-01-12 | Jadolabs Gmbh | Sphingolipid-derived pharmaceutical compositions |
| JP2006045113A (ja) | 2004-08-04 | 2006-02-16 | Kemikurea:Kk | リン酸エステル類 |
| JP4825947B2 (ja) | 2004-08-04 | 2011-11-30 | 学校法人関西学院 | 不飽和アミノジオール類の製造方法 |
| US8206750B2 (en) | 2005-03-24 | 2012-06-26 | Cerenis Therapeutics Holding S.A. | Charged lipoprotein complexes and their uses |
| AR057456A1 (es) | 2005-07-20 | 2007-12-05 | Merck & Co Inc | Inhibidores de la proteasa ns3 del vhc |
| JP2007204384A (ja) | 2006-01-31 | 2007-08-16 | Kemikurea:Kk | 光学活性リン酸誘導体およびこれを用いた光学活性スフィンゴシン１−リン酸誘導体の製造方法 |
| JP5429734B2 (ja) * | 2007-02-09 | 2014-02-26 | 国立大学法人岐阜大学 | スフィンゴ糖脂質の合成法 |
| JP5178707B2 (ja) | 2007-03-09 | 2013-04-10 | 株式会社糖鎖工学研究所 | スフィンゴシン化合物、その製造方法及びスフィンゴミエリナーゼ阻害剤 |
| CN102223878A (zh) | 2008-10-07 | 2011-10-19 | 耶路撒冷希伯来大学伊森姆研究发展公司 | 包含鞘磷脂的脂质体系统 |
| HUE042314T2 (hu) | 2011-02-07 | 2019-06-28 | Cerenis Therapeutics Holding Sa | Lipoprotein komplexek és azok gyártása és alkalmazásai |
| FR3000959B1 (fr) * | 2013-01-14 | 2015-08-21 | Holis Technologies | Nouveaux intermediaires de synthese permettant d'acceder avec de bons rendements a des derives de sphingosines, ceramides et sphingomyelines |
| US9708354B2 (en) | 2013-03-15 | 2017-07-18 | Cerenis Therapeutics Holding Sa | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
| JP6438417B2 (ja) | 2013-03-15 | 2018-12-12 | セレニス セラピューティクス ホールディング エスアー | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
-
2014
- 2014-03-14 JP JP2015562366A patent/JP6438417B2/ja active Active
- 2014-03-14 EP EP18160532.0A patent/EP3363805B1/en active Active
- 2014-03-14 EP EP14729036.5A patent/EP2970344A2/en not_active Withdrawn
- 2014-03-14 MX MX2015012877A patent/MX387128B/es unknown
- 2014-03-14 WO PCT/IB2014/000494 patent/WO2014140787A2/en not_active Ceased
- 2014-03-14 SG SG10201804887YA patent/SG10201804887YA/en unknown
- 2014-03-14 US US14/213,269 patent/US20140316154A1/en not_active Abandoned
- 2014-03-14 BR BR112015023558A patent/BR112015023558A2/pt not_active Application Discontinuation
- 2014-03-14 DK DK18160532.0T patent/DK3363805T3/da active
- 2014-03-14 AU AU2014229638A patent/AU2014229638B2/en active Active
- 2014-03-14 HK HK16102047.1A patent/HK1214266A1/zh unknown
- 2014-03-14 EP EP20214357.4A patent/EP3842443B1/en active Active
- 2014-03-14 CA CA2900902A patent/CA2900902C/en active Active
- 2014-03-14 CN CN201480015700.6A patent/CN105051051B/zh active Active
- 2014-03-14 KR KR1020157025911A patent/KR20150132188A/ko not_active Withdrawn
- 2014-03-14 ES ES20214357T patent/ES3017659T3/es active Active
- 2014-03-14 SG SG11201506456VA patent/SG11201506456VA/en unknown
-
2015
- 2015-04-22 US US14/693,520 patent/US9643915B2/en active Active
- 2015-08-14 ZA ZA2015/05860A patent/ZA201505860B/en unknown
- 2015-08-19 PH PH12015501835A patent/PH12015501835B1/en unknown
-
2017
- 2017-04-04 US US15/478,532 patent/US20170204122A1/en not_active Abandoned
-
2018
- 2018-06-21 JP JP2018117808A patent/JP2018168171A/ja active Pending
- 2018-11-21 AU AU2018267598A patent/AU2018267598A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX387128B (es) | Métodos para la síntesis de esfingomielinas y dihidroesfingomielinas. | |
| CL2015002742A1 (es) | Moléculas de unión para bcma y cd3. | |
| ZA201707967B (en) | Antibody constructs for cd70 and cd3 | |
| CL2016000460A1 (es) | Proteínas de unión al antígeno gitr | |
| CR20150247A (es) | Anticuerpos de antihemaglutinina y métodos de uso | |
| CR20150046A (es) | Anticuerpos anti-cd79b e inmunoconjugados | |
| MX2015012326A (es) | Anticuerpos anti-crth2 y su uso. | |
| CR20150482A (es) | Anticuerpos e inmunoconjugados anti-b7-h4 | |
| CR20150049A (es) | Anticuerpos e inmunoconjugados anti-cd79b | |
| CL2016001432A1 (es) | Nuevos anticuerpos anti-dpep3 y métodos de uso | |
| MX2015013901A (es) | Anticuerpos anti-il-4 y anticuerpos biespecificos y sus usos. | |
| MX2015017341A (es) | Anticuerpos anti-factor del complemento c1q y uso de los mismos. | |
| IN2014DN05885A (OSRAM) | ||
| EP2859350A4 (en) | USE OF 5-ALA FOR DETECTION OF CEREBRAL TUMORS | |
| IN2013MU00848A (OSRAM) | ||
| AR097668A1 (es) | Colorante-polímero | |
| MX2014014381A (es) | Anticuerpos de anti-teofilina y metodos de uso. | |
| ZA201603457B (en) | Novel method for the synthesis of agomelatine | |
| PH12016501201A1 (en) | Synthesis of ent-progesterone and intermediates thereof | |
| EP3684647A4 (en) | SUB-INSTRUMENT PANEL EMERGENCY VISION DEVICE | |
| MX2015012902A (es) | Sintesis de ent-progesterona e intermediarios de la misma. | |
| PH12018500508A1 (en) | Methods for the synthesis of spingomyelins and dihydrosphingomyelins | |
| BR112018007282A2 (pt) | métodos para síntese total de resolvina e1 | |
| MX2015010789A (es) | Anticuerpos anti-pcsm. | |
| DE112014003192A5 (de) | Verfahren zur Biosynthese von spezifisch isotopenmarkierten Sekundärmetaboliten |