MX381426B - Preparacion de citrato de sufentanilo y base de sufentanilo. - Google Patents

Preparacion de citrato de sufentanilo y base de sufentanilo.

Info

Publication number
MX381426B
MX381426B MX2017015100A MX2017015100A MX381426B MX 381426 B MX381426 B MX 381426B MX 2017015100 A MX2017015100 A MX 2017015100A MX 2017015100 A MX2017015100 A MX 2017015100A MX 381426 B MX381426 B MX 381426B
Authority
MX
Mexico
Prior art keywords
sufentanil
citrate
base
preparation
sufentanil citrate
Prior art date
Application number
MX2017015100A
Other languages
English (en)
Spanish (es)
Other versions
MX2017015100A (es
Inventor
Brian Orr
George Helmut Klemm
Joel Mcclenaghan
Original Assignee
Mallinckrodt Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Llc filed Critical Mallinckrodt Llc
Publication of MX2017015100A publication Critical patent/MX2017015100A/es
Publication of MX381426B publication Critical patent/MX381426B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MX2017015100A 2015-05-27 2016-05-25 Preparacion de citrato de sufentanilo y base de sufentanilo. MX381426B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562166911P 2015-05-27 2015-05-27
PCT/US2016/034091 WO2016191472A1 (en) 2015-05-27 2016-05-25 Preparation of sufentanil citrate and sufentanil base

Publications (2)

Publication Number Publication Date
MX2017015100A MX2017015100A (es) 2018-08-09
MX381426B true MX381426B (es) 2025-03-12

Family

ID=57393664

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017015100A MX381426B (es) 2015-05-27 2016-05-25 Preparacion de citrato de sufentanilo y base de sufentanilo.

Country Status (10)

Country Link
US (5) US10227335B2 (pl)
EP (1) EP3302473B1 (pl)
JP (4) JP2018515580A (pl)
AU (1) AU2016268344B2 (pl)
BR (1) BR112017025115B1 (pl)
CA (1) CA2986764A1 (pl)
ES (1) ES2806631T3 (pl)
MX (1) MX381426B (pl)
PL (1) PL3302473T3 (pl)
WO (1) WO2016191472A1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018515580A (ja) 2015-05-27 2018-06-14 マリンクロッド エルエルシー スフェンタニルクエン酸塩及びスフェンタニル塩の調合

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998834A (en) * 1975-03-14 1976-12-21 Janssen Pharmaceutica N.V. N-(4-piperidinyl)-n-phenylamides and -carbamates
US4179569A (en) * 1975-03-14 1979-12-18 Janssen Pharmaceutica N.V. N-(4-piperidinyl)-N-phenylamides
US5039804A (en) * 1989-12-13 1991-08-13 Glaxo Inc. Preparation of substituted alkali metal piperidine-4-carboxylates
US5489689A (en) 1993-09-30 1996-02-06 Mallinckrodt Chemical, Inc. Preparation of piperidine derivatives
US6342250B1 (en) * 1997-09-25 2002-01-29 Gel-Del Technologies, Inc. Drug delivery devices comprising biodegradable protein for the controlled release of pharmacologically active agents and method of making the drug delivery devices
EP1246801B1 (en) 1999-12-06 2006-09-20 Mallinckrodt Inc. Methods for the syntheses of alfentanil, sufentanil and remifentanil
DE60210794T2 (de) * 2001-10-17 2007-05-10 E.I. Dupont De Nemours And Co., Wilmington Rotor-stator apparat und verfahren zur bildung von partikeln
WO2008005423A1 (en) * 2006-07-03 2008-01-10 Cambrex Charles City, Inc. Improved method of making sufentanil
AU2008216867B2 (en) 2007-02-09 2014-01-30 Durect Corporation Transoral dosage forms comprising sufentanil and naloxone
US20100056574A1 (en) * 2008-09-04 2010-03-04 Mallinckrodt Inc. Crystalline Forms of Sufentanil
WO2010053944A1 (en) 2008-11-04 2010-05-14 Cambrex Charles City, Inc. Improved method of making piperidine derivatives
EP2616464B1 (en) * 2010-09-17 2018-01-03 Mallinckrodt LLC Improved process for the preparation of a precursor of sufentanil base
EP2455377B1 (de) 2010-11-11 2014-07-09 hameln rds gmbh Synthese von Fentanyl Analoga
CN102060753B (zh) * 2010-12-29 2013-01-09 宜昌人福药业有限责任公司 一种4-苯胺基哌啶类镇痛药的精制方法
JP6146613B2 (ja) 2013-09-04 2017-06-14 東芝ライテック株式会社 自動車用照明装置、および自動車用灯具
JP2018515580A (ja) 2015-05-27 2018-06-14 マリンクロッド エルエルシー スフェンタニルクエン酸塩及びスフェンタニル塩の調合

Also Published As

Publication number Publication date
US20160347743A1 (en) 2016-12-01
EP3302473A4 (en) 2019-04-17
WO2016191472A1 (en) 2016-12-01
ES2806631T3 (es) 2021-02-18
JP7525589B2 (ja) 2024-07-30
JP2023036903A (ja) 2023-03-14
US10227335B2 (en) 2019-03-12
EP3302473A1 (en) 2018-04-11
BR112017025115B1 (pt) 2023-03-14
US20250368630A1 (en) 2025-12-04
JP2018515580A (ja) 2018-06-14
BR112017025115A2 (pt) 2018-07-31
EP3302473B1 (en) 2020-07-08
US20210061793A1 (en) 2021-03-04
US20190152961A1 (en) 2019-05-23
JP2021059609A (ja) 2021-04-15
US10899749B2 (en) 2021-01-26
US12371423B2 (en) 2025-07-29
CA2986764A1 (en) 2016-12-01
MX2017015100A (es) 2018-08-09
AU2016268344B2 (en) 2020-03-26
JP7857352B2 (ja) 2026-05-12
JP2024138039A (ja) 2024-10-07
PL3302473T3 (pl) 2020-12-14
US20230074804A1 (en) 2023-03-09
AU2016268344A1 (en) 2017-11-30

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