MX377622B - Suspensión que comprende hidróxido de aluminio e hidróxido de magnesio y método de preparación de la misma. - Google Patents
Suspensión que comprende hidróxido de aluminio e hidróxido de magnesio y método de preparación de la misma.Info
- Publication number
- MX377622B MX377622B MX2019012084A MX2019012084A MX377622B MX 377622 B MX377622 B MX 377622B MX 2019012084 A MX2019012084 A MX 2019012084A MX 2019012084 A MX2019012084 A MX 2019012084A MX 377622 B MX377622 B MX 377622B
- Authority
- MX
- Mexico
- Prior art keywords
- hydroxide
- aluminum hydroxide
- magnesium hydroxide
- present
- aqueous suspension
- Prior art date
Links
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 title abstract 3
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 title abstract 3
- 229910001862 magnesium hydroxide Inorganic materials 0.000 title abstract 3
- 239000000347 magnesium hydroxide Substances 0.000 title abstract 3
- 239000000725 suspension Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 4
- 239000007900 aqueous suspension Substances 0.000 abstract 3
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000375 suspending agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Jellies, Jams, And Syrups (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
La presente invención proporciona una suspensión que comprende hidróxido de aluminio e hidróxido de magnesio y un método de preparación de la misma. La composición de suspensión acuosa de acuerdo con la presente invención garantiza una excelente velocidad de sedimentación mediante el uso de un agente de suspensión mixto con una composición específica, de manera que el hidróxido de aluminio y el hidróxido de magnesio insolubles no se sedimenten fácilmente, no formen una torta y se redispersen fácilmente. Puesto que la composición de suspensión acuosa que tiene una excelente velocidad de sedimentación no solo tiene estabilidad física, sino que también forma un sistema de dispersión homogéneo, puede garantizarse la reproducibilidad o eficacia de la biodisponibilidad. Además, la composición de suspensión acuosa de acuerdo con la presente invención proporciona una textura excelente y, por tanto, el cumplimiento del paciente aumenta.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710240597.0A CN108721213A (zh) | 2017-04-13 | 2017-04-13 | 铝镁混悬液及其制备方法 |
| PCT/KR2018/004305 WO2018190659A1 (ko) | 2017-04-13 | 2018-04-12 | 수산화알루미늄과 수산화마그네슘을 포함하는 현탁액 및 그 제조방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019012084A MX2019012084A (es) | 2020-01-20 |
| MX377622B true MX377622B (es) | 2025-03-10 |
Family
ID=63793453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019012084A MX377622B (es) | 2017-04-13 | 2018-04-12 | Suspensión que comprende hidróxido de aluminio e hidróxido de magnesio y método de preparación de la misma. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US11135165B2 (es) |
| EP (1) | EP3610857B1 (es) |
| JP (1) | JP7090641B2 (es) |
| KR (1) | KR102396359B1 (es) |
| CN (2) | CN108721213A (es) |
| AU (1) | AU2018251519B2 (es) |
| CA (1) | CA3059031C (es) |
| CO (1) | CO2019012413A2 (es) |
| ES (1) | ES2908336T3 (es) |
| MX (1) | MX377622B (es) |
| PH (1) | PH12019502323B1 (es) |
| PL (1) | PL3610857T3 (es) |
| SA (1) | SA519410276B1 (es) |
| WO (1) | WO2018190659A1 (es) |
| ZA (1) | ZA201906662B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108721213A (zh) | 2017-04-13 | 2018-11-02 | 辽宁大熊制药有限公司 | 铝镁混悬液及其制备方法 |
| CN114028331B (zh) * | 2021-11-03 | 2022-11-18 | 北京鑫开元医药科技有限公司 | 镁加铝混悬液及其制备工艺 |
| KR102788240B1 (ko) * | 2023-01-17 | 2025-04-01 | 주식회사 금강건설 | 야간 시인성이 향상된 노면표지용 도료 조성물 |
| CN117159461A (zh) * | 2023-07-26 | 2023-12-05 | 合肥远志医药科技开发有限公司 | 一种铝碳酸镁混悬液及其制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3272704A (en) | 1963-06-06 | 1966-09-13 | Armour Pharma | Stable aluminum hydroxide-magnesium compound codried gel antacids and process of making the same |
| US3591680A (en) * | 1969-11-17 | 1971-07-06 | Smith Kline French Lab | Concentrated antacid compositions and method of producing antacid activity |
| US4443433A (en) | 1981-11-13 | 1984-04-17 | Warner-Lambert Company | Antacid material based on magnesium aluminum hydroxide and preparation thereof |
| US5272137A (en) * | 1992-02-14 | 1993-12-21 | Mcneil-Pfc, Inc. | Aqueous pharmaceutical suspension for pharmaceutical actives |
| US5593489A (en) | 1995-10-20 | 1997-01-14 | Ecc International Inc. | Acid resistant carbonate composition containing an aluminum or magnesium hydroxide methods of preparation and uses therefor |
| US5914135A (en) * | 1997-04-16 | 1999-06-22 | Mcneil-Ppc, Inc. | Liquid antacid compositions |
| AU4759099A (en) * | 1998-09-21 | 2000-03-23 | Mcneil-Ppc, Inc. | Heat stable antacid and antigas suspensions |
| KR20000046974A (ko) * | 1998-12-31 | 2000-07-25 | 윤재승 | 아세글루타미드 알루미늄의 경구 투여용 제제 조성물ㅇ |
| US20030232092A1 (en) * | 2002-06-14 | 2003-12-18 | Hasenmayer Donald L. | Liquid antacid compositions |
| MY151468A (en) * | 2005-12-28 | 2014-05-30 | Takeda Pharmaceutical | Controlled release solid preparation |
| CN101002939A (zh) * | 2007-01-12 | 2007-07-25 | 广东华南药业有限公司 | 一类治疗与胃酸有关疾病的药物组合制剂 |
| CN101002769A (zh) * | 2007-01-12 | 2007-07-25 | 广东华南药业有限公司 | 奥美拉唑组合物制剂 |
| US20130243888A1 (en) * | 2010-07-27 | 2013-09-19 | Sara Beth Ford | Composition and Method for the Topical Treatment of Dermatitis |
| CN102319208A (zh) * | 2011-09-23 | 2012-01-18 | 何雪心 | 一种治疗化放疗所致口腔黏膜炎的悬浮液组合物 |
| CN104173372A (zh) * | 2014-09-03 | 2014-12-03 | 左克源 | 治疗口腔粘膜炎的组合物及其制备方法与应用包装 |
| CN105853352B (zh) * | 2016-05-19 | 2018-12-25 | 武汉先路医药科技股份有限公司 | 一种含有普拉洛芬的混悬液处方组成及其制备方法 |
| CN108721213A (zh) | 2017-04-13 | 2018-11-02 | 辽宁大熊制药有限公司 | 铝镁混悬液及其制备方法 |
-
2017
- 2017-04-13 CN CN201710240597.0A patent/CN108721213A/zh active Pending
-
2018
- 2018-04-12 CN CN201880001603.XA patent/CN109414406B/zh active Active
- 2018-04-12 ES ES18783778T patent/ES2908336T3/es active Active
- 2018-04-12 CA CA3059031A patent/CA3059031C/en active Active
- 2018-04-12 JP JP2019555963A patent/JP7090641B2/ja active Active
- 2018-04-12 MX MX2019012084A patent/MX377622B/es active IP Right Grant
- 2018-04-12 AU AU2018251519A patent/AU2018251519B2/en active Active
- 2018-04-12 KR KR1020197029219A patent/KR102396359B1/ko active Active
- 2018-04-12 US US16/604,167 patent/US11135165B2/en active Active
- 2018-04-12 WO PCT/KR2018/004305 patent/WO2018190659A1/ko not_active Ceased
- 2018-04-12 PL PL18783778T patent/PL3610857T3/pl unknown
- 2018-04-12 EP EP18783778.6A patent/EP3610857B1/en active Active
-
2019
- 2019-10-09 ZA ZA2019/06662A patent/ZA201906662B/en unknown
- 2019-10-09 SA SA519410276A patent/SA519410276B1/ar unknown
- 2019-10-10 PH PH12019502323A patent/PH12019502323B1/en unknown
- 2019-11-05 CO CONC2019/0012413A patent/CO2019012413A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2020516660A (ja) | 2020-06-11 |
| ES2908336T3 (es) | 2022-04-28 |
| PH12019502323A1 (en) | 2020-07-06 |
| CN109414406B (zh) | 2019-12-13 |
| WO2018190659A1 (ko) | 2018-10-18 |
| MX2019012084A (es) | 2020-01-20 |
| JP7090641B2 (ja) | 2022-06-24 |
| US11135165B2 (en) | 2021-10-05 |
| PL3610857T3 (pl) | 2022-06-20 |
| CN109414406A (zh) | 2019-03-01 |
| EP3610857A1 (en) | 2020-02-19 |
| RU2019131244A (ru) | 2021-04-05 |
| AU2018251519B2 (en) | 2023-06-15 |
| EP3610857A4 (en) | 2020-09-16 |
| CO2019012413A2 (es) | 2020-01-17 |
| US20200113826A1 (en) | 2020-04-16 |
| AU2018251519A1 (en) | 2019-11-14 |
| ZA201906662B (en) | 2021-06-30 |
| PH12019502323B1 (en) | 2020-07-06 |
| RU2019131244A3 (es) | 2021-06-30 |
| CA3059031A1 (en) | 2018-10-18 |
| EP3610857B1 (en) | 2022-02-09 |
| CN108721213A (zh) | 2018-11-02 |
| KR102396359B1 (ko) | 2022-05-10 |
| CA3059031C (en) | 2022-08-16 |
| BR112019021477A2 (pt) | 2020-05-12 |
| SA519410276B1 (ar) | 2024-01-30 |
| KR20190130590A (ko) | 2019-11-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |