MX376386B - Composiciones para usarse en el tratamiento de patologías del tejido de cartílago y disco. - Google Patents

Composiciones para usarse en el tratamiento de patologías del tejido de cartílago y disco.

Info

Publication number
MX376386B
MX376386B MX2016002556A MX2016002556A MX376386B MX 376386 B MX376386 B MX 376386B MX 2016002556 A MX2016002556 A MX 2016002556A MX 2016002556 A MX2016002556 A MX 2016002556A MX 376386 B MX376386 B MX 376386B
Authority
MX
Mexico
Prior art keywords
sub
cartilage
compositions
treatment
disc tissue
Prior art date
Application number
MX2016002556A
Other languages
English (en)
Other versions
MX2016002556A (es
Inventor
Fackson Mwale
John Antoniou
Laura M Epure
Lisbet Haglund
Michael P Grant
Peter J Roughley
Rahul Gawri
Original Assignee
The Royal Institution For The Advancement Of Learning/Mcgill Univ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Royal Institution For The Advancement Of Learning/Mcgill Univ filed Critical The Royal Institution For The Advancement Of Learning/Mcgill Univ
Publication of MX2016002556A publication Critical patent/MX2016002556A/es
Publication of MX376386B publication Critical patent/MX376386B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Wood Science & Technology (AREA)
  • Peptides Or Proteins (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Un polipéptido aislado que comprende un péptido seleccionado de: i) DHX1SDNYT, en donde X1 es L o H (SEQ ID NO:3); ii) una variante conservadora de i); iii) un fragmento de i) o ii); donde la variante conservadora y/o fragmento retiene la actividad biológica y el péptido tiene 15 o menos aminoácidos así como células recombinantes, y sus usos.
MX2016002556A 2013-08-27 2014-08-27 Composiciones para usarse en el tratamiento de patologías del tejido de cartílago y disco. MX376386B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361870394P 2013-08-27 2013-08-27
US201461975329P 2014-04-04 2014-04-04
PCT/CA2014/000656 WO2015027322A1 (en) 2013-08-27 2014-08-27 Methods and compositions for treatment of cartilage and disc tissue pathologies

Publications (2)

Publication Number Publication Date
MX2016002556A MX2016002556A (es) 2016-10-26
MX376386B true MX376386B (es) 2025-03-07

Family

ID=52585327

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016002556A MX376386B (es) 2013-08-27 2014-08-27 Composiciones para usarse en el tratamiento de patologías del tejido de cartílago y disco.

Country Status (12)

Country Link
US (3) US10202420B2 (es)
EP (1) EP3039032B1 (es)
JP (1) JP6700182B2 (es)
KR (1) KR102369010B1 (es)
CN (1) CN105940011B (es)
AU (2) AU2014311219B2 (es)
CA (1) CA2957965C (es)
ES (1) ES2883567T3 (es)
IL (1) IL244282B (es)
MX (1) MX376386B (es)
WO (1) WO2015027322A1 (es)
ZA (1) ZA201601963B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6700182B2 (ja) 2013-08-27 2020-05-27 ザ ロイヤル インスティチューション フォー ザ アドバンスメント オブ ラーニング/マギル ユニバーシティ 軟骨及び椎間板組織病理の治療のためのポリペプチド及び組成物
CN111939323B (zh) * 2020-08-08 2022-06-10 武汉速普生物科技有限公司 含有透明质酸连接肽和连接蛋白末端肽的功能性多肽水凝胶及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2443147A1 (en) * 2001-04-10 2002-10-24 Agensys, Inc. Nucleic acid and corresponding protein entitled 184p1e2 useful in treatment and detection of cancer
WO2002083920A2 (en) * 2001-04-10 2002-10-24 Agensys, Inc. Nucleic acid sequences useful in the detection and treatment of various cancers
JP6700182B2 (ja) * 2013-08-27 2020-05-27 ザ ロイヤル インスティチューション フォー ザ アドバンスメント オブ ラーニング/マギル ユニバーシティ 軟骨及び椎間板組織病理の治療のためのポリペプチド及び組成物

Also Published As

Publication number Publication date
JP6700182B2 (ja) 2020-05-27
CA2957965C (en) 2023-03-28
JP2016534117A (ja) 2016-11-04
AU2014311219A1 (en) 2016-04-21
KR20160058109A (ko) 2016-05-24
WO2015027322A1 (en) 2015-03-05
US20160207959A1 (en) 2016-07-21
US10202420B2 (en) 2019-02-12
KR102369010B1 (ko) 2022-03-02
US20190375788A1 (en) 2019-12-12
AU2019201512A1 (en) 2019-03-28
IL244282A0 (en) 2016-04-21
EP3039032B1 (en) 2021-05-19
MX2016002556A (es) 2016-10-26
ES2883567T3 (es) 2021-12-09
AU2014311219B2 (en) 2018-12-06
EP3039032A1 (en) 2016-07-06
ZA201601963B (en) 2022-08-31
IL244282B (en) 2021-09-30
CN105940011B (zh) 2021-01-05
EP3039032A4 (en) 2017-04-19
US20210079040A1 (en) 2021-03-18
CA2957965A1 (en) 2015-03-05
CN105940011A (zh) 2016-09-14

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