MX368621B - Solucion acuosa clara. - Google Patents

Solucion acuosa clara.

Info

Publication number
MX368621B
MX368621B MX2015009895A MX2015009895A MX368621B MX 368621 B MX368621 B MX 368621B MX 2015009895 A MX2015009895 A MX 2015009895A MX 2015009895 A MX2015009895 A MX 2015009895A MX 368621 B MX368621 B MX 368621B
Authority
MX
Mexico
Prior art keywords
aqueous solution
clear aqueous
formula
c6h5ch2n
benzisoxazole
Prior art date
Application number
MX2015009895A
Other languages
English (en)
Other versions
MX2015009895A (es
Inventor
Yuko Shikamura
Yuka Higashimura
Original Assignee
Senju Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharma Co filed Critical Senju Pharma Co
Publication of MX2015009895A publication Critical patent/MX2015009895A/es
Publication of MX368621B publication Critical patent/MX368621B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

La presente invención proporciona una preparación líquida acuosa y estable que contiene ácido (3-{2-[4-isopropil-2-(4-trifluorometi l)fenil-5-tiazolil]etil}-5-metil-1,2-bencisoxazol-6-il)oxiacético o una sal farmacéuticamente aceptable del mismo como un ingrediente activo, y cloruro de benzalconio representado por la fórmula: [C6H5CH2N(CH3)2R)Cl en donde R es un grupo alquilo que tiene de 8 a 18 átomos de carbono.
MX2015009895A 2013-01-31 2014-01-30 Solucion acuosa clara. MX368621B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2013017876 2013-01-31
JP2013267724 2013-12-25
PCT/JP2014/052041 WO2014119643A1 (ja) 2013-01-31 2014-01-30 澄明な水性液剤

Publications (2)

Publication Number Publication Date
MX2015009895A MX2015009895A (es) 2015-09-24
MX368621B true MX368621B (es) 2019-10-08

Family

ID=51262354

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015009895A MX368621B (es) 2013-01-31 2014-01-30 Solucion acuosa clara.

Country Status (10)

Country Link
US (2) US9968679B2 (es)
EP (1) EP2952189B1 (es)
JP (1) JP5753958B2 (es)
KR (1) KR20150110773A (es)
CN (1) CN105025896B (es)
BR (1) BR112015017919A8 (es)
CA (1) CA2899237A1 (es)
MX (1) MX368621B (es)
RU (1) RU2662067C2 (es)
WO (1) WO2014119643A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105007918B (zh) * 2013-01-31 2018-06-15 千寿制药株式会社 稳定的水性液体制剂
KR20200100676A (ko) 2017-12-20 2020-08-26 이에이 파마 가부시키가이샤 유지 투석 하의 2차성 부갑상선 기능 항진증의 예방 또는 치료용 의약 조성물
US20220142958A1 (en) * 2019-04-03 2022-05-12 Ea Pharma Co., Ltd. Medicinal composition having excellent stability

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0283318A (ja) 1988-09-20 1990-03-23 Zeria Pharmaceut Co Ltd 安定な点眼剤
JP4171529B2 (ja) 1995-06-26 2008-10-22 大正製薬株式会社 点眼剤の充填容器
JPH11228404A (ja) 1997-12-11 1999-08-24 Senju Pharmaceut Co Ltd 安定な水性点眼剤
CN1228053C (zh) * 2001-09-11 2005-11-23 参天制药株式会社 含有二尿苷磷酸的滴眼液
JP2003160491A (ja) * 2001-09-11 2003-06-03 Santen Pharmaceut Co Ltd ジウリジンリン酸含有点眼液
MXPA04003398A (es) 2001-10-12 2004-11-22 Nippon Chemiphar Co Activador para el receptor o activado con el proliferador de peroxisoma.
JP4402591B2 (ja) 2002-07-16 2010-01-20 千寿製薬株式会社 薬液容器及びその製造方法
JP2004123729A (ja) * 2002-09-09 2004-04-22 Santen Pharmaceut Co Ltd ラタノプロストを有効成分とする澄明な点眼液
CA2707067C (en) 2002-09-09 2013-07-16 Santen Pharmaceutical Co., Ltd. Clear ophthalmic solution comprising latanoprost as active ingredient
CN101278936B (zh) * 2002-09-09 2012-10-31 参天制药株式会社 含有效成分拉坦前列素的澄明滴眼剂
US8129431B2 (en) 2003-01-21 2012-03-06 Senju Pharmaceutical Co., Ltd. Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid
EP2151438B1 (en) * 2007-05-21 2012-10-31 Senju Pharmaceutical Co., Ltd. Pharmaceutical containing ppar-delta agonist
AU2008329876A1 (en) 2007-11-27 2009-06-04 Alcon Research, Ltd. Topical ophthalmic or otic solution formulations containing moxifloxacin hydrochloride and dexamethasone phosphate
WO2011034192A1 (ja) * 2009-09-17 2011-03-24 千寿製薬株式会社 ラタノプロストを含有する水性点眼剤、並びにラタノプロストの樹脂への吸着の抑制方法
CN105007918B (zh) 2013-01-31 2018-06-15 千寿制药株式会社 稳定的水性液体制剂
CN204146320U (zh) 2014-06-06 2015-02-11 黄金珍 电子烟雾化器

Also Published As

Publication number Publication date
US20150366969A1 (en) 2015-12-24
US9968679B2 (en) 2018-05-15
BR112015017919A2 (pt) 2017-07-11
EP2952189A1 (en) 2015-12-09
KR20150110773A (ko) 2015-10-02
CN105025896B (zh) 2017-11-14
BR112015017919A8 (pt) 2019-11-05
WO2014119643A1 (ja) 2014-08-07
RU2015135974A (ru) 2017-03-03
EP2952189B1 (en) 2019-09-18
MX2015009895A (es) 2015-09-24
CN105025896A (zh) 2015-11-04
EP2952189A4 (en) 2016-08-31
JPWO2014119643A1 (ja) 2017-01-26
CA2899237A1 (en) 2014-08-07
US10709786B2 (en) 2020-07-14
US20180228901A1 (en) 2018-08-16
JP5753958B2 (ja) 2015-07-22
RU2662067C2 (ru) 2018-07-23

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