MX365408B - Solución acuosa estable. - Google Patents

Solución acuosa estable.

Info

Publication number
MX365408B
MX365408B MX2015009894A MX2015009894A MX365408B MX 365408 B MX365408 B MX 365408B MX 2015009894 A MX2015009894 A MX 2015009894A MX 2015009894 A MX2015009894 A MX 2015009894A MX 365408 B MX365408 B MX 365408B
Authority
MX
Mexico
Prior art keywords
aqueous solution
stable aqueous
octoxynol
tyloxapol
benzisoxazole
Prior art date
Application number
MX2015009894A
Other languages
English (en)
Other versions
MX2015009894A (es
Inventor
Yuko Shikamura
Yuka Higashimura
Original Assignee
Senju Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharma Co filed Critical Senju Pharma Co
Publication of MX2015009894A publication Critical patent/MX2015009894A/es
Publication of MX365408B publication Critical patent/MX365408B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

La presente invención proporciona una preparación líquida acuosa que tiene alta estabilidad a la luz y al calor, que comprende el ácido (3-{2-[4-isopropil-2-(4-trifluorometil)fenil-5-tiazolil)etil }-5-metil-1,2-bencisoxazol-6-iI)oxiacético o una sal farmacéuticamente aceptable del mismo y tiloxapol u octoxinol.
MX2015009894A 2013-01-31 2014-01-30 Solución acuosa estable. MX365408B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2013017877 2013-01-31
JP2013171433 2013-08-21
PCT/JP2014/052040 WO2014119642A1 (ja) 2013-01-31 2014-01-30 安定な水性液剤

Publications (2)

Publication Number Publication Date
MX2015009894A MX2015009894A (es) 2015-09-24
MX365408B true MX365408B (es) 2019-05-31

Family

ID=51262353

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015009894A MX365408B (es) 2013-01-31 2014-01-30 Solución acuosa estable.

Country Status (12)

Country Link
US (1) US20150366966A1 (es)
EP (1) EP2952190B1 (es)
JP (1) JP5753957B2 (es)
KR (1) KR20150110775A (es)
CN (2) CN108606951A (es)
BR (1) BR112015017708A2 (es)
CA (1) CA2899292A1 (es)
ES (1) ES2650748T3 (es)
MX (1) MX365408B (es)
PL (1) PL2952190T3 (es)
RU (1) RU2665639C2 (es)
WO (1) WO2014119642A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9968679B2 (en) 2013-01-31 2018-05-15 Senju Pharmaceutical Co., Ltd. Clear aqueous solution
CN110621298B (zh) 2017-05-11 2022-12-20 维卢玛有限公司 阿托品药物组合物
CN117571642A (zh) * 2024-01-12 2024-02-20 天津世纪康泰生物医学工程有限公司 一种泰洛沙泊分光光度检测方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5414011A (en) * 1987-09-11 1995-05-09 Syntex (U.S.A.) Inc. Preservative system for ophthalmic formulations
JP4171529B2 (ja) 1995-06-26 2008-10-22 大正製薬株式会社 点眼剤の充填容器
JPH11228404A (ja) * 1997-12-11 1999-08-24 Senju Pharmaceut Co Ltd 安定な水性点眼剤
CA2439100A1 (en) * 2001-02-26 2002-09-06 Kowa Company, Ltd. Eye drop
JP4276074B2 (ja) 2001-10-12 2009-06-10 日本ケミファ株式会社 ペルオキシソーム増殖剤応答性受容体δの活性化剤
WO2004006826A1 (ja) 2002-07-16 2004-01-22 Senju Pharmaceutical Co., Ltd. 薬液容器及びその製造方法
EP1586316B1 (en) * 2003-01-21 2008-04-30 Senju Pharmaceutical Co., Ltd. Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid
JP2005247800A (ja) * 2004-03-08 2005-09-15 Zeria Pharmaceut Co Ltd 点眼剤
EP2151438B1 (en) 2007-05-21 2012-10-31 Senju Pharmaceutical Co., Ltd. Pharmaceutical containing ppar-delta agonist
JP5668476B2 (ja) * 2007-10-08 2015-02-12 オーリニア・ファーマシューティカルズ・インコーポレイテッドＡｕｒｉｎｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． カルシニューリン阻害剤またはｍＴＯＲ阻害剤を含む眼科用組成物
US9968679B2 (en) * 2013-01-31 2018-05-15 Senju Pharmaceutical Co., Ltd. Clear aqueous solution
RU2635185C2 (ru) * 2013-12-17 2017-11-09 Иван Дмитриевич Захаров Фармацевтический препарат для профилактики и лечения прогрессирующей близорукости

Also Published As

Publication number Publication date
WO2014119642A1 (ja) 2014-08-07
CN105007918A (zh) 2015-10-28
CN105007918B (zh) 2018-06-15
JPWO2014119642A1 (ja) 2017-01-26
CA2899292A1 (en) 2014-08-07
BR112015017708A2 (pt) 2017-07-11
PL2952190T3 (pl) 2018-02-28
MX2015009894A (es) 2015-09-24
EP2952190B1 (en) 2017-09-06
EP2952190A4 (en) 2016-08-24
JP5753957B2 (ja) 2015-07-22
US20150366966A1 (en) 2015-12-24
RU2665639C2 (ru) 2018-09-03
ES2650748T3 (es) 2018-01-22
KR20150110775A (ko) 2015-10-02
CN108606951A (zh) 2018-10-02
EP2952190A1 (en) 2015-12-09
RU2015136804A (ru) 2017-03-06

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