MX366134B - Angiotensina en el tratamiento de condiciones cerebrales. - Google Patents
Angiotensina en el tratamiento de condiciones cerebrales.Info
- Publication number
- MX366134B MX366134B MX2015003968A MX2015003968A MX366134B MX 366134 B MX366134 B MX 366134B MX 2015003968 A MX2015003968 A MX 2015003968A MX 2015003968 A MX2015003968 A MX 2015003968A MX 366134 B MX366134 B MX 366134B
- Authority
- MX
- Mexico
- Prior art keywords
- angiotensin
- treating brain
- brain conditions
- conditions
- methods
- Prior art date
Links
- 210000004556 brain Anatomy 0.000 title abstract 3
- 102000015427 Angiotensins Human genes 0.000 title 1
- 108010064733 Angiotensins Proteins 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 108010021281 angiotensin I (1-7) Proteins 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007920 subcutaneous administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/085—Angiotensins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Hematology (AREA)
- Zoology (AREA)
Abstract
La presente invención se refiere a métodos y composiciones para tratar condiciones cerebrales. En algunas modalidades, los métodos incluyen administrar a un sujeto que sufre de o es susceptible a una condición cerebral un péptido de angiotensina (1-7) por vía de una ruta de administración ya sea intravenosa o subcutánea.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261708793P | 2012-10-02 | 2012-10-02 | |
US201261720299P | 2012-10-30 | 2012-10-30 | |
PCT/US2013/062969 WO2014055591A1 (en) | 2012-10-02 | 2013-10-02 | Angiotensin in treating brain conditions |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015003968A MX2015003968A (es) | 2016-02-05 |
MX366134B true MX366134B (es) | 2019-06-28 |
Family
ID=49919223
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015003968A MX366134B (es) | 2012-10-02 | 2013-10-02 | Angiotensina en el tratamiento de condiciones cerebrales. |
Country Status (11)
Country | Link |
---|---|
US (4) | US8633158B1 (es) |
EP (1) | EP2903605B1 (es) |
JP (2) | JP6302916B2 (es) |
KR (1) | KR20150067228A (es) |
CN (1) | CN104837485A (es) |
AU (2) | AU2013327453A1 (es) |
CA (1) | CA2885912A1 (es) |
ES (1) | ES2689781T3 (es) |
MX (1) | MX366134B (es) |
RU (2) | RU2018120387A (es) |
WO (1) | WO2014055591A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8633158B1 (en) | 2012-10-02 | 2014-01-21 | Tarix Pharmaceuticals Ltd. | Angiotensin in treating brain conditions |
AU2014284496A1 (en) | 2013-07-03 | 2016-01-21 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Method for treating cognitive dysfunction |
US9333233B2 (en) | 2014-02-25 | 2016-05-10 | Tarix Pharmaceuticals Ltd. | Methods and compositions for the delayed treatment of stroke |
WO2016010844A1 (en) * | 2014-07-14 | 2016-01-21 | Tarix Pharmaceuticals Ltd | Methods and compositions for the treatment of stroke |
US10183055B2 (en) | 2014-07-21 | 2019-01-22 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Ang-(1-7) derivative oligopeptides for the treatment of pain and other indications |
US9796759B2 (en) | 2014-07-21 | 2017-10-24 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Ang-(1-7) derivative oligopeptides and methods for using and producing the same |
CN106699843B (zh) * | 2015-07-13 | 2020-07-28 | 首都医科大学 | RGDVGRPAK-The十肽,其制备,活性及应用 |
CN106699844B (zh) * | 2015-07-13 | 2020-07-03 | 首都医科大学 | The-RGDVGRPAK十肽,其制备,活性及应用 |
WO2018129511A2 (en) * | 2017-01-09 | 2018-07-12 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Ang-(1-7) and derivative oligopeptides for the treatment of traumatic brain injury and other cognitive impairments |
CN109553658B (zh) * | 2018-12-13 | 2022-10-04 | 重庆大学 | Ang-(1-7)的氮杂多肽类似物、制备方法及应用 |
Family Cites Families (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4244946A (en) | 1979-06-11 | 1981-01-13 | The Salk Institute For Biological Studies | Water-soluble peptides affecting gonadal function |
US4305872A (en) | 1979-10-19 | 1981-12-15 | Kenneth Wingrove | Polypeptide derivatives |
US4316891A (en) | 1980-06-14 | 1982-02-23 | The Salk Institute For Biological Studies | Extended N-terminal somatostatin |
SU1067796A1 (ru) | 1981-10-30 | 1986-01-15 | Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвсср | Циклический аналог ангиотензина,обладающий способностью ингибировать прессорное и миотропное действие ангиотензина |
AU697504B2 (en) | 1993-09-24 | 1998-10-08 | University Of Southern California | Use of angiotensin II analogs in tissue repair |
CA2172493C (en) | 1993-09-24 | 2003-09-16 | Kathleen Elizabeth Rodgers | Use of angiotensin iii and analogs thereof in tissue repair |
US5955430A (en) | 1993-09-24 | 1999-09-21 | University Of Southern California | Use of angiotensin II fragments and analogs thereof in tissue repair |
US5834432A (en) | 1995-06-06 | 1998-11-10 | The University Of Southern California | Use of angiotensin II Type 2 receptor agonists in tissue repair |
JP2001500475A (ja) | 1996-07-12 | 2001-01-16 | マクギル ユニバーシティ | 細胞接着を調節するための化合物および方法 |
US6110895A (en) | 1996-12-16 | 2000-08-29 | University Of Southern California | Method of promoting healing in skin grafts |
US6335195B1 (en) | 1997-01-28 | 2002-01-01 | Maret Corporation | Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation |
US5917151A (en) | 1997-08-29 | 1999-06-29 | Ut Automotive Dearborn, Inc. | Multi-shot molds for manufacturing wire harnesses |
SG92610A1 (en) | 1997-10-24 | 2002-11-19 | Univ Singapore | The use of des-aspartate-angiotensin i as an agent for the treatment and prevention of neointima formation, restenosis, and arteriosclerosis |
WO1999026644A1 (en) | 1997-11-26 | 1999-06-03 | University Of Southern California | Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation |
US6248587B1 (en) | 1997-11-26 | 2001-06-19 | University Of Southern Cailfornia | Method for promoting mesenchymal stem and lineage-specific cell proliferation |
US6239109B1 (en) | 1998-02-09 | 2001-05-29 | University Of Southern California | Method of promoting erythropoiesis |
WO1999045945A1 (en) | 1998-03-10 | 1999-09-16 | University Of Southern California | Improved radiation therapy methods |
US7173011B2 (en) | 2000-11-20 | 2007-02-06 | University Of Southern California | Radiation therapy methods |
US6455500B1 (en) | 1998-03-10 | 2002-09-24 | University Of Southern California | Radiation therapy methods |
WO1999046285A2 (en) | 1998-03-11 | 1999-09-16 | University Of Southern California | Method of promoting production of living tissue equivalents |
JP2002511416A (ja) | 1998-04-09 | 2002-04-16 | ユニヴァースティ オブ サザーン カリフォルニア | 感染を処置および予防するための方法 |
US6762167B1 (en) | 1998-05-11 | 2004-07-13 | University Of Southern California | Methods for treating a patient undergoing chemotherapy |
CA2322963C (en) | 1998-05-11 | 2004-04-13 | University Of Southern California | Methods to increase white blood cell survival after chemotherapy |
US6916783B2 (en) | 1998-07-13 | 2005-07-12 | University Of Southern California | Methods for accelerating bone and cartilage growth and repair |
CA2328871C (en) | 1998-07-13 | 2002-10-01 | University Of Southern California | Methods for accelerating bone and cartilage growth and repair |
AU755943B2 (en) | 1998-08-13 | 2003-01-02 | University Of Southern California | Methods to increase blood flow to ischemic tissue |
ES2267513T3 (es) | 1999-03-23 | 2007-03-16 | University Of Southern California | Angiotensina ii y analogos de la misma para limitar la formacion de cicatrices y de adherencias. |
US6730775B1 (en) | 1999-03-23 | 2004-05-04 | University Of Southern California | Methods for limiting scar and adhesion formation |
YU78601A (sh) | 1999-05-05 | 2005-07-19 | Aventis Pharma Deutschland Gmbh. | 1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže |
US7338938B2 (en) | 1999-05-10 | 2008-03-04 | University Of Southern California | Methods for treating a patient undergoing chemotherapy |
US6821953B1 (en) | 1999-12-16 | 2004-11-23 | University Of Southern California | Methods for treating and preventing damage to mucosal tissue |
AU1792901A (en) | 1999-12-16 | 2001-06-25 | University Of Southern California | Methods for treating and preventing diabetic complications |
CA2393755C (en) | 1999-12-16 | 2010-09-21 | The University Of Southern California | Methods for treating and preventing damage to mucosal tissue |
AU2001231154A1 (en) | 2000-01-24 | 2001-07-31 | Adherex Technologies Inc. | Peptidomimetic modulators of cell adhesion |
WO2001098325A1 (en) | 2000-06-19 | 2001-12-27 | University Of Southern California | Methods for treating and preventing alopecia |
US6747008B1 (en) | 2000-06-19 | 2004-06-08 | University Of Southern California | Methods for treating and preventing alopecia |
AU2002308522A1 (en) | 2001-05-01 | 2002-11-11 | University Of Southern California | Methods for inhibiting tumor cell proliferation |
BRPI0105509B8 (pt) | 2001-11-05 | 2021-05-25 | Univ Minas Gerais | formulações do peptídeo angiotensina-(1-7) usando as ciclodextrinas, lipossomas e o polímero plga |
AU2002364381A1 (en) | 2001-11-23 | 2003-06-10 | Solvay Pharmaceuticals Gmbh | Hypertonia treatment during the acute phase of a cerebrovascular accident |
DE10306179A1 (de) * | 2003-02-13 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe |
BRPI0502497A (pt) | 2005-06-28 | 2007-02-06 | Univ Minas Gerais | uso de agonistas e antagonistas do receptor acoplado a proteìna g, mas, como moduladores de atividade apoptótica para o estudo, a prevenção e o tratamento de doenças |
BRPI0602366B1 (pt) | 2006-04-26 | 2017-12-12 | Universidade Federal De Minas Gerais | Use of agonists of the receptor coupled to protein g, but, in the treatment of metabolic syndrome, its components and their complications |
WO2008130217A1 (en) | 2006-08-08 | 2008-10-30 | Applied Nanosystems B.V. | Cyclic angiotensin analogs |
AT506258A1 (de) | 2007-12-18 | 2009-07-15 | Apeiron Biolog Forschungs Und | Behandlung inflammatorischer krankheiten |
EP2077119A1 (de) | 2007-12-21 | 2009-07-08 | Apeiron Biologics Forschungs- und Entwicklungsgesellschaft M.B.H. | Behandlung von Fibrosen und Lebererkrankungen |
BRPI0800585B8 (pt) * | 2008-02-13 | 2021-05-25 | Univ Minas Gerais | composições farmacêuticas do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7) e uso do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7) |
US20090227507A1 (en) | 2008-03-10 | 2009-09-10 | University Of Southern California | Angiotensin (1-7) Dosage Forms and Uses Thereof |
AT506632A1 (de) | 2008-04-09 | 2009-10-15 | Apeiron Biolog Forschungs Und | Behandlung von tumorerkrankungen |
ES2393455T3 (es) | 2008-09-12 | 2012-12-21 | Charité-Universitátsmedizin Berlin (Charité) | Uso de un agonista del receptor Ang-(1-7) en lesiones pulmonares agudas |
CL2008003736A1 (es) | 2008-12-15 | 2009-05-29 | Univ Pontificia Catolica Chile | Uso de angiotensina (1-9) para preparar un medicamento, util para prevenir, revertir y/o disminuir el remodelado cardiovascular, pulmonar, renal y/o cerebral. |
US20120070403A1 (en) | 2009-02-17 | 2012-03-22 | Sygnis Bioscience Gmbh & Co. Kg | Use of g-csf for the extension of the therapeutic time-window of thrombolytic stroke therapy |
EP2455388A1 (en) * | 2010-11-23 | 2012-05-23 | LanthioPep B.V. | Novel angiotensin type 2 (AT2) receptor agonists and uses thereof. |
JP2015508759A (ja) | 2012-02-10 | 2015-03-23 | タリックス ファーマシューティカルズ リミテッド | 末梢血管疾患を処置するための組成物および方法 |
US8633158B1 (en) | 2012-10-02 | 2014-01-21 | Tarix Pharmaceuticals Ltd. | Angiotensin in treating brain conditions |
US9333233B2 (en) | 2014-02-25 | 2016-05-10 | Tarix Pharmaceuticals Ltd. | Methods and compositions for the delayed treatment of stroke |
-
2013
- 2013-01-28 US US13/752,202 patent/US8633158B1/en active Active
- 2013-05-17 US US13/897,051 patent/US9511055B2/en active Active
- 2013-10-02 RU RU2018120387A patent/RU2018120387A/ru not_active Application Discontinuation
- 2013-10-02 CN CN201380062800.XA patent/CN104837485A/zh active Pending
- 2013-10-02 CA CA2885912A patent/CA2885912A1/en not_active Abandoned
- 2013-10-02 WO PCT/US2013/062969 patent/WO2014055591A1/en active Application Filing
- 2013-10-02 MX MX2015003968A patent/MX366134B/es active IP Right Grant
- 2013-10-02 EP EP13844187.8A patent/EP2903605B1/en active Active
- 2013-10-02 JP JP2015534823A patent/JP6302916B2/ja active Active
- 2013-10-02 RU RU2015110114A patent/RU2661109C2/ru not_active IP Right Cessation
- 2013-10-02 AU AU2013327453A patent/AU2013327453A1/en not_active Abandoned
- 2013-10-02 KR KR1020157011035A patent/KR20150067228A/ko not_active Application Discontinuation
- 2013-10-02 ES ES13844187.8T patent/ES2689781T3/es active Active
-
2016
- 2016-10-24 US US15/332,813 patent/US20170258766A1/en not_active Abandoned
-
2018
- 2018-01-12 US US15/870,233 patent/US20190000809A1/en not_active Abandoned
- 2018-03-05 JP JP2018038469A patent/JP6472914B2/ja active Active
- 2018-07-13 AU AU2018205186A patent/AU2018205186B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US8633158B1 (en) | 2014-01-21 |
US20190000809A1 (en) | 2019-01-03 |
US9511055B2 (en) | 2016-12-06 |
WO2014055591A1 (en) | 2014-04-10 |
KR20150067228A (ko) | 2015-06-17 |
AU2018205186B2 (en) | 2020-04-09 |
US20170258766A1 (en) | 2017-09-14 |
EP2903605A1 (en) | 2015-08-12 |
JP2015532291A (ja) | 2015-11-09 |
EP2903605A4 (en) | 2016-03-23 |
CN104837485A (zh) | 2015-08-12 |
RU2018120387A (ru) | 2018-11-15 |
US20140094497A1 (en) | 2014-04-03 |
AU2013327453A1 (en) | 2015-04-09 |
CA2885912A1 (en) | 2014-04-10 |
MX2015003968A (es) | 2016-02-05 |
ES2689781T3 (es) | 2018-11-15 |
JP2018090625A (ja) | 2018-06-14 |
AU2018205186A1 (en) | 2018-08-02 |
RU2015110114A (ru) | 2016-11-27 |
JP6472914B2 (ja) | 2019-02-20 |
RU2661109C2 (ru) | 2018-07-11 |
JP6302916B2 (ja) | 2018-03-28 |
EP2903605B1 (en) | 2018-08-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2018205186B2 (en) | Angiotensin in treating brain conditions | |
AU2018253544A1 (en) | Methods for treating or preventing asthma by administering an IL-4R antagonist | |
MX2013010376A (es) | Formulaciones estables para inyeccion parenteral de farmacos de peptido. | |
PH12014501702A1 (en) | Imidazopyrrolidinone compounds | |
IN2015DN01156A (es) | ||
NZ709392A (en) | Synergistic bacterial compositions and methods of production and use thereof | |
MX2019014761A (es) | Manejo de toxicidad para actividad antitumoral de cars. | |
SG10201804552WA (en) | Nanoparticle compositions, formulations thereof, and uses therefor | |
MX350378B (es) | Mejora del transporte de moleculas terapeuticas a traves de la barrera hematoencefalica. | |
WO2014052360A3 (en) | Glycoprotein preparations | |
MX2013004061A (es) | Analogos de ciclosporina. | |
NZ744862A (en) | Combination therapies for melanoma comprising administering cobimetinib and vemurafenib | |
MX2012007806A (es) | Composiciones farmaceuticas para administracion oral de peptidos de insulina. | |
MY172699A (en) | Implantable medical devices with increased immune tolerance, and methods for making and implanting | |
MX2015003048A (es) | Tratamiento del trastorno de estres post-traumatico con mycobacterium aislado. | |
MX2019001977A (es) | Metodos y composiciones para tratar esclerosis multiple y trastornos relacionados. | |
MX2013004062A (es) | Analogos de ciclosporina. | |
MX2021002513A (es) | Composicion que comprende desintegrina y metaloproteinasa con motivos tipo i de trombospondina 13 (adamts13) para administracion subcutanea. | |
MY191932A (en) | Chitosan-derived compositions | |
MD20140123A2 (ro) | Agenţi terapeutici optimizaţi pentru administrare subcutanată | |
MX2015009277A (es) | Formas de dosificacion y usos terapauticos de l-4-cloro quinurenina. | |
GB201013785D0 (en) | Treatment | |
GB201115977D0 (en) | Neurodevelopmental disorders | |
MX2014006990A (es) | Tratamiento para diabetes tipo i y tipo ii. | |
GB201114923D0 (en) | Immunogenic proteins and compositions |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |