MX366134B - Angiotensina en el tratamiento de condiciones cerebrales. - Google Patents
Angiotensina en el tratamiento de condiciones cerebrales.Info
- Publication number
- MX366134B MX366134B MX2015003968A MX2015003968A MX366134B MX 366134 B MX366134 B MX 366134B MX 2015003968 A MX2015003968 A MX 2015003968A MX 2015003968 A MX2015003968 A MX 2015003968A MX 366134 B MX366134 B MX 366134B
- Authority
- MX
- Mexico
- Prior art keywords
- angiotensin
- treating brain
- brain conditions
- conditions
- methods
- Prior art date
Links
- 210000004556 brain Anatomy 0.000 title abstract 3
- 102000015427 Angiotensins Human genes 0.000 title 1
- 108010064733 Angiotensins Proteins 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 108010021281 angiotensin I (1-7) Proteins 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007920 subcutaneous administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/085—Angiotensins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Hematology (AREA)
- Zoology (AREA)
Abstract
La presente invención se refiere a métodos y composiciones para tratar condiciones cerebrales. En algunas modalidades, los métodos incluyen administrar a un sujeto que sufre de o es susceptible a una condición cerebral un péptido de angiotensina (1-7) por vía de una ruta de administración ya sea intravenosa o subcutánea.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261708793P | 2012-10-02 | 2012-10-02 | |
| US201261720299P | 2012-10-30 | 2012-10-30 | |
| PCT/US2013/062969 WO2014055591A1 (en) | 2012-10-02 | 2013-10-02 | Angiotensin in treating brain conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015003968A MX2015003968A (es) | 2016-02-05 |
| MX366134B true MX366134B (es) | 2019-06-28 |
Family
ID=49919223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015003968A MX366134B (es) | 2012-10-02 | 2013-10-02 | Angiotensina en el tratamiento de condiciones cerebrales. |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US8633158B1 (es) |
| EP (1) | EP2903605B1 (es) |
| JP (2) | JP6302916B2 (es) |
| KR (1) | KR20150067228A (es) |
| CN (1) | CN104837485A (es) |
| AU (2) | AU2013327453A1 (es) |
| CA (1) | CA2885912A1 (es) |
| ES (1) | ES2689781T3 (es) |
| MX (1) | MX366134B (es) |
| RU (2) | RU2018120387A (es) |
| WO (1) | WO2014055591A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8633158B1 (en) | 2012-10-02 | 2014-01-21 | Tarix Pharmaceuticals Ltd. | Angiotensin in treating brain conditions |
| WO2015002903A1 (en) * | 2013-07-03 | 2015-01-08 | Arizona Board Of Regents For The University Of Arizona | Method for treating cognitive dysfunction |
| US9333233B2 (en) * | 2014-02-25 | 2016-05-10 | Tarix Pharmaceuticals Ltd. | Methods and compositions for the delayed treatment of stroke |
| WO2016010844A1 (en) * | 2014-07-14 | 2016-01-21 | Tarix Pharmaceuticals Ltd | Methods and compositions for the treatment of stroke |
| US10183055B2 (en) | 2014-07-21 | 2019-01-22 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Ang-(1-7) derivative oligopeptides for the treatment of pain and other indications |
| AU2015294371B2 (en) * | 2014-07-21 | 2018-02-01 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Ang-(1-7) derivative oligopeptides and methods for using and producing the same |
| CN106699844B (zh) * | 2015-07-13 | 2020-07-03 | 首都医科大学 | The-RGDVGRPAK十肽,其制备,活性及应用 |
| CN106699843B (zh) * | 2015-07-13 | 2020-07-28 | 首都医科大学 | RGDVGRPAK-The十肽,其制备,活性及应用 |
| WO2018129511A2 (en) * | 2017-01-09 | 2018-07-12 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Ang-(1-7) and derivative oligopeptides for the treatment of traumatic brain injury and other cognitive impairments |
| CN109553658B (zh) * | 2018-12-13 | 2022-10-04 | 重庆大学 | Ang-(1-7)的氮杂多肽类似物、制备方法及应用 |
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| US4244946A (en) | 1979-06-11 | 1981-01-13 | The Salk Institute For Biological Studies | Water-soluble peptides affecting gonadal function |
| US4305872A (en) | 1979-10-19 | 1981-12-15 | Kenneth Wingrove | Polypeptide derivatives |
| US4316891A (en) | 1980-06-14 | 1982-02-23 | The Salk Institute For Biological Studies | Extended N-terminal somatostatin |
| SU1067796A1 (ru) | 1981-10-30 | 1986-01-15 | Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвсср | Циклический аналог ангиотензина,обладающий способностью ингибировать прессорное и миотропное действие ангиотензина |
| US5955430A (en) | 1993-09-24 | 1999-09-21 | University Of Southern California | Use of angiotensin II fragments and analogs thereof in tissue repair |
| JPH09503205A (ja) | 1993-09-24 | 1997-03-31 | ザ ユニバーシティ オブ サザーン カリフォルニア | 組織修復におけるアンギオテンシン▲ii▼類似体の使用 |
| ES2168312T3 (es) | 1993-09-24 | 2002-06-16 | Univ Southern California | Utilizacion de angiotensina iii y sus analogos para la reparacion tisular. |
| US5834432A (en) | 1995-06-06 | 1998-11-10 | The University Of Southern California | Use of angiotensin II Type 2 receptor agonists in tissue repair |
| US20020168761A1 (en) | 2000-01-24 | 2002-11-14 | Gour Barbara J. | Peptidomimetic modulators of cell adhesion |
| JP2001500475A (ja) | 1996-07-12 | 2001-01-16 | マクギル ユニバーシティ | 細胞接着を調節するための化合物および方法 |
| US6110895A (en) | 1996-12-16 | 2000-08-29 | University Of Southern California | Method of promoting healing in skin grafts |
| US6335195B1 (en) | 1997-01-28 | 2002-01-01 | Maret Corporation | Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation |
| US5917151A (en) | 1997-08-29 | 1999-06-29 | Ut Automotive Dearborn, Inc. | Multi-shot molds for manufacturing wire harnesses |
| SG92610A1 (en) | 1997-10-24 | 2002-11-19 | Univ Singapore | The use of des-aspartate-angiotensin i as an agent for the treatment and prevention of neointima formation, restenosis, and arteriosclerosis |
| US6248587B1 (en) | 1997-11-26 | 2001-06-19 | University Of Southern Cailfornia | Method for promoting mesenchymal stem and lineage-specific cell proliferation |
| AU1706399A (en) | 1997-11-26 | 1999-06-15 | University Of Southern California | Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation |
| AU2591699A (en) | 1998-02-09 | 1999-08-23 | University Of Southern California | Method of promoting erythropoiesis |
| US7173011B2 (en) | 2000-11-20 | 2007-02-06 | University Of Southern California | Radiation therapy methods |
| US6455500B1 (en) | 1998-03-10 | 2002-09-24 | University Of Southern California | Radiation therapy methods |
| CA2323237C (en) | 1998-03-10 | 2009-05-19 | University Of Southern California | Improved radiation therapy methods |
| US6498138B1 (en) | 1998-03-11 | 2002-12-24 | University Of Southern California | Method of promoting production of living tissue equivalents |
| EP1067952A1 (en) | 1998-04-09 | 2001-01-17 | University Of Southern California | Methods for treatment and prevention of infections |
| US6762167B1 (en) | 1998-05-11 | 2004-07-13 | University Of Southern California | Methods for treating a patient undergoing chemotherapy |
| JP2003521441A (ja) | 1998-05-11 | 2003-07-15 | ユニヴァースティ オブ サザーン カリフォルニア | 化学療法後の白血球生残率を増加させる方法 |
| US6916783B2 (en) | 1998-07-13 | 2005-07-12 | University Of Southern California | Methods for accelerating bone and cartilage growth and repair |
| ATE250423T1 (de) | 1998-07-13 | 2003-10-15 | Univ Southern California | Verfahren zur beschleunigen den zuwachs und heilen von knochen und knorpel |
| CA2339330A1 (en) | 1998-08-13 | 2000-02-24 | University Of Southern California | Methods to increase blood flow to ischemic tissue |
| EP1165099B1 (en) | 1999-03-23 | 2006-08-09 | University Of Southern California | Angiotensin ii and analogs thereof for limiting scar and adhesion formation |
| US6730775B1 (en) | 1999-03-23 | 2004-05-04 | University Of Southern California | Methods for limiting scar and adhesion formation |
| YU78601A (sh) | 1999-05-05 | 2005-07-19 | Aventis Pharma Deutschland Gmbh. | 1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže |
| US7338938B2 (en) | 1999-05-10 | 2008-03-04 | University Of Southern California | Methods for treating a patient undergoing chemotherapy |
| AU1792901A (en) | 1999-12-16 | 2001-06-25 | University Of Southern California | Methods for treating and preventing diabetic complications |
| US6821953B1 (en) | 1999-12-16 | 2004-11-23 | University Of Southern California | Methods for treating and preventing damage to mucosal tissue |
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| US6747008B1 (en) | 2000-06-19 | 2004-06-08 | University Of Southern California | Methods for treating and preventing alopecia |
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| US7122523B2 (en) | 2001-05-01 | 2006-10-17 | University Of Southern California | Methods for inhibiting tumor cell proliferation |
| BRPI0105509B8 (pt) | 2001-11-05 | 2021-05-25 | Univ Minas Gerais | formulações do peptídeo angiotensina-(1-7) usando as ciclodextrinas, lipossomas e o polímero plga |
| BR0214383A (pt) | 2001-11-23 | 2004-11-03 | Solvay Pharm Gmbh | Tratamento de hipertonia durante a fase aguda do ataque de apoplexia |
| DE10306179A1 (de) * | 2003-02-13 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe |
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| AT506258A1 (de) | 2007-12-18 | 2009-07-15 | Apeiron Biolog Forschungs Und | Behandlung inflammatorischer krankheiten |
| EP2077119A1 (de) | 2007-12-21 | 2009-07-08 | Apeiron Biologics Forschungs- und Entwicklungsgesellschaft M.B.H. | Behandlung von Fibrosen und Lebererkrankungen |
| BRPI0800585B8 (pt) * | 2008-02-13 | 2021-05-25 | Univ Minas Gerais | composições farmacêuticas do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7) e uso do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7) |
| WO2009114461A2 (en) | 2008-03-10 | 2009-09-17 | University Of Southern California | Angiotensin (1-7) dosage forms and uses thereof |
| AT506632A1 (de) | 2008-04-09 | 2009-10-15 | Apeiron Biolog Forschungs Und | Behandlung von tumorerkrankungen |
| ES2393455T3 (es) * | 2008-09-12 | 2012-12-21 | Charité-Universitátsmedizin Berlin (Charité) | Uso de un agonista del receptor Ang-(1-7) en lesiones pulmonares agudas |
| CL2008003736A1 (es) | 2008-12-15 | 2009-05-29 | Univ Pontificia Catolica Chile | Uso de angiotensina (1-9) para preparar un medicamento, util para prevenir, revertir y/o disminuir el remodelado cardiovascular, pulmonar, renal y/o cerebral. |
| CN102316891A (zh) | 2009-02-17 | 2012-01-11 | 森格尼斯生物科学有限两合公司 | G-csf用于延长卒中溶栓治疗的治疗时间窗的用途 |
| EP2455388A1 (en) * | 2010-11-23 | 2012-05-23 | LanthioPep B.V. | Novel angiotensin type 2 (AT2) receptor agonists and uses thereof. |
| KR20140140546A (ko) | 2012-02-10 | 2014-12-09 | 타릭스 파마슈티컬스 엘티디. | 말초 혈관 질환의 치료를 위한 조성물 및 방법 |
| US8633158B1 (en) | 2012-10-02 | 2014-01-21 | Tarix Pharmaceuticals Ltd. | Angiotensin in treating brain conditions |
| US9333233B2 (en) | 2014-02-25 | 2016-05-10 | Tarix Pharmaceuticals Ltd. | Methods and compositions for the delayed treatment of stroke |
-
2013
- 2013-01-28 US US13/752,202 patent/US8633158B1/en active Active
- 2013-05-17 US US13/897,051 patent/US9511055B2/en active Active
- 2013-10-02 CN CN201380062800.XA patent/CN104837485A/zh active Pending
- 2013-10-02 CA CA2885912A patent/CA2885912A1/en not_active Abandoned
- 2013-10-02 RU RU2018120387A patent/RU2018120387A/ru not_active Application Discontinuation
- 2013-10-02 EP EP13844187.8A patent/EP2903605B1/en active Active
- 2013-10-02 RU RU2015110114A patent/RU2661109C2/ru not_active IP Right Cessation
- 2013-10-02 MX MX2015003968A patent/MX366134B/es active IP Right Grant
- 2013-10-02 ES ES13844187.8T patent/ES2689781T3/es active Active
- 2013-10-02 KR KR1020157011035A patent/KR20150067228A/ko not_active Ceased
- 2013-10-02 JP JP2015534823A patent/JP6302916B2/ja active Active
- 2013-10-02 AU AU2013327453A patent/AU2013327453A1/en not_active Abandoned
- 2013-10-02 WO PCT/US2013/062969 patent/WO2014055591A1/en not_active Ceased
-
2016
- 2016-10-24 US US15/332,813 patent/US20170258766A1/en not_active Abandoned
-
2018
- 2018-01-12 US US15/870,233 patent/US20190000809A1/en not_active Abandoned
- 2018-03-05 JP JP2018038469A patent/JP6472914B2/ja active Active
- 2018-07-13 AU AU2018205186A patent/AU2018205186B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018090625A (ja) | 2018-06-14 |
| US8633158B1 (en) | 2014-01-21 |
| AU2018205186A1 (en) | 2018-08-02 |
| EP2903605A1 (en) | 2015-08-12 |
| RU2661109C2 (ru) | 2018-07-11 |
| JP6472914B2 (ja) | 2019-02-20 |
| AU2013327453A1 (en) | 2015-04-09 |
| EP2903605A4 (en) | 2016-03-23 |
| RU2018120387A (ru) | 2018-11-15 |
| MX2015003968A (es) | 2016-02-05 |
| AU2018205186B2 (en) | 2020-04-09 |
| US20170258766A1 (en) | 2017-09-14 |
| ES2689781T3 (es) | 2018-11-15 |
| CA2885912A1 (en) | 2014-04-10 |
| JP2015532291A (ja) | 2015-11-09 |
| WO2014055591A1 (en) | 2014-04-10 |
| EP2903605B1 (en) | 2018-08-15 |
| US9511055B2 (en) | 2016-12-06 |
| KR20150067228A (ko) | 2015-06-17 |
| CN104837485A (zh) | 2015-08-12 |
| US20140094497A1 (en) | 2014-04-03 |
| US20190000809A1 (en) | 2019-01-03 |
| RU2015110114A (ru) | 2016-11-27 |
| JP6302916B2 (ja) | 2018-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |