MX366134B - Angiotensina en el tratamiento de condiciones cerebrales. - Google Patents
Angiotensina en el tratamiento de condiciones cerebrales.Info
- Publication number
- MX366134B MX366134B MX2015003968A MX2015003968A MX366134B MX 366134 B MX366134 B MX 366134B MX 2015003968 A MX2015003968 A MX 2015003968A MX 2015003968 A MX2015003968 A MX 2015003968A MX 366134 B MX366134 B MX 366134B
- Authority
- MX
- Mexico
- Prior art keywords
- angiotensin
- treating brain
- brain conditions
- conditions
- methods
- Prior art date
Links
- 210000004556 brain Anatomy 0.000 title abstract 3
- 102000015427 Angiotensins Human genes 0.000 title 1
- 108010064733 Angiotensins Proteins 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 108010021281 angiotensin I (1-7) Proteins 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007920 subcutaneous administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/085—Angiotensins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Hematology (AREA)
- Zoology (AREA)
Abstract
La presente invención se refiere a métodos y composiciones para tratar condiciones cerebrales. En algunas modalidades, los métodos incluyen administrar a un sujeto que sufre de o es susceptible a una condición cerebral un péptido de angiotensina (1-7) por vía de una ruta de administración ya sea intravenosa o subcutánea.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261708793P | 2012-10-02 | 2012-10-02 | |
| US201261720299P | 2012-10-30 | 2012-10-30 | |
| PCT/US2013/062969 WO2014055591A1 (en) | 2012-10-02 | 2013-10-02 | Angiotensin in treating brain conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015003968A MX2015003968A (es) | 2016-02-05 |
| MX366134B true MX366134B (es) | 2019-06-28 |
Family
ID=49919223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015003968A MX366134B (es) | 2012-10-02 | 2013-10-02 | Angiotensina en el tratamiento de condiciones cerebrales. |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US8633158B1 (es) |
| EP (1) | EP2903605B1 (es) |
| JP (2) | JP6302916B2 (es) |
| KR (1) | KR20150067228A (es) |
| CN (1) | CN104837485A (es) |
| AU (2) | AU2013327453A1 (es) |
| CA (1) | CA2885912A1 (es) |
| ES (1) | ES2689781T3 (es) |
| MX (1) | MX366134B (es) |
| RU (2) | RU2661109C2 (es) |
| WO (1) | WO2014055591A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8633158B1 (en) | 2012-10-02 | 2014-01-21 | Tarix Pharmaceuticals Ltd. | Angiotensin in treating brain conditions |
| WO2015002903A1 (en) * | 2013-07-03 | 2015-01-08 | Arizona Board Of Regents For The University Of Arizona | Method for treating cognitive dysfunction |
| US9333233B2 (en) | 2014-02-25 | 2016-05-10 | Tarix Pharmaceuticals Ltd. | Methods and compositions for the delayed treatment of stroke |
| WO2016010844A1 (en) * | 2014-07-14 | 2016-01-21 | Tarix Pharmaceuticals Ltd | Methods and compositions for the treatment of stroke |
| US10183055B2 (en) | 2014-07-21 | 2019-01-22 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Ang-(1-7) derivative oligopeptides for the treatment of pain and other indications |
| JP6666899B2 (ja) | 2014-07-21 | 2020-03-18 | アリゾナ ボード オブ リージェンツ オン ビハーフ オブ ザ ユニヴァーシティー オブ アリゾナ | Ang−(1−7)誘導体オリゴペプチド、ならびにそれを使用および作製するための方法 |
| CN106699843B (zh) * | 2015-07-13 | 2020-07-28 | 首都医科大学 | RGDVGRPAK-The十肽,其制备,活性及应用 |
| CN106699844B (zh) * | 2015-07-13 | 2020-07-03 | 首都医科大学 | The-RGDVGRPAK十肽,其制备,活性及应用 |
| EP3565824A2 (en) * | 2017-01-09 | 2019-11-13 | ARIZONA BOARD OF REGENTS on behalf of THE UNIVERSITY OF ARIZONA | Ang-(1-7) and derivative oligopeptides for the treatment of traumatic brain injury and other cognitive impairments |
| CN109553658B (zh) * | 2018-12-13 | 2022-10-04 | 重庆大学 | Ang-(1-7)的氮杂多肽类似物、制备方法及应用 |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4244946A (en) | 1979-06-11 | 1981-01-13 | The Salk Institute For Biological Studies | Water-soluble peptides affecting gonadal function |
| US4305872A (en) | 1979-10-19 | 1981-12-15 | Kenneth Wingrove | Polypeptide derivatives |
| US4316891A (en) | 1980-06-14 | 1982-02-23 | The Salk Institute For Biological Studies | Extended N-terminal somatostatin |
| SU1067796A1 (ru) | 1981-10-30 | 1986-01-15 | Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвсср | Циклический аналог ангиотензина,обладающий способностью ингибировать прессорное и миотропное действие ангиотензина |
| US5955430A (en) | 1993-09-24 | 1999-09-21 | University Of Southern California | Use of angiotensin II fragments and analogs thereof in tissue repair |
| DK0730465T3 (da) | 1993-09-24 | 2002-04-08 | Univ Southern California | Anvendelse af angiotensin III og analoger dertil til vævsreparation |
| ATE473995T1 (de) | 1993-09-24 | 2010-07-15 | Univ Southern California | Verwendung von angiotensin-ii-analogen zur gewebewiederherstellung |
| US5834432A (en) | 1995-06-06 | 1998-11-10 | The University Of Southern California | Use of angiotensin II Type 2 receptor agonists in tissue repair |
| AU722985B2 (en) | 1996-07-12 | 2000-08-17 | Mcgill University | Compounds and methods for modulating cell adhesion |
| US20020168761A1 (en) | 2000-01-24 | 2002-11-14 | Gour Barbara J. | Peptidomimetic modulators of cell adhesion |
| US6110895A (en) | 1996-12-16 | 2000-08-29 | University Of Southern California | Method of promoting healing in skin grafts |
| US6335195B1 (en) | 1997-01-28 | 2002-01-01 | Maret Corporation | Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation |
| US5917151A (en) | 1997-08-29 | 1999-06-29 | Ut Automotive Dearborn, Inc. | Multi-shot molds for manufacturing wire harnesses |
| SG92610A1 (en) | 1997-10-24 | 2002-11-19 | Univ Singapore | The use of des-aspartate-angiotensin i as an agent for the treatment and prevention of neointima formation, restenosis, and arteriosclerosis |
| US6248587B1 (en) | 1997-11-26 | 2001-06-19 | University Of Southern Cailfornia | Method for promoting mesenchymal stem and lineage-specific cell proliferation |
| AU1706399A (en) | 1997-11-26 | 1999-06-15 | University Of Southern California | Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation |
| WO1999040106A2 (en) | 1998-02-09 | 1999-08-12 | University Of Southern California | Use of angiotensin analogues for promoting erythropoiesis |
| US7173011B2 (en) | 2000-11-20 | 2007-02-06 | University Of Southern California | Radiation therapy methods |
| EP1061937A1 (en) | 1998-03-10 | 2000-12-27 | University Of Southern California | Improved radiation therapy methods |
| US6455500B1 (en) | 1998-03-10 | 2002-09-24 | University Of Southern California | Radiation therapy methods |
| AU3077299A (en) | 1998-03-11 | 1999-09-27 | University Of Southern California | Method of promoting production of living tissue equivalents |
| AU752041B2 (en) | 1998-04-09 | 2002-09-05 | University Of Southern California | Methods for treatment and prevention of infections |
| US6762167B1 (en) | 1998-05-11 | 2004-07-13 | University Of Southern California | Methods for treating a patient undergoing chemotherapy |
| US6475988B1 (en) | 1998-05-11 | 2002-11-05 | University Of Southern California | Methods to increase white blood cell survival after chemotherapy |
| US6916783B2 (en) | 1998-07-13 | 2005-07-12 | University Of Southern California | Methods for accelerating bone and cartilage growth and repair |
| JP3686335B2 (ja) | 1998-07-13 | 2005-08-24 | ユニヴァースティ オブ サザーン カリフォルニア | 骨および軟骨成長と修復を促進する方法 |
| AU755943B2 (en) | 1998-08-13 | 2003-01-02 | University Of Southern California | Methods to increase blood flow to ischemic tissue |
| US6730775B1 (en) | 1999-03-23 | 2004-05-04 | University Of Southern California | Methods for limiting scar and adhesion formation |
| AU756156B2 (en) | 1999-03-23 | 2003-01-02 | University Of Southern California | Methods for limiting scar and adhesion formation |
| YU78601A (sh) | 1999-05-05 | 2005-07-19 | Aventis Pharma Deutschland Gmbh. | 1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže |
| US7338938B2 (en) | 1999-05-10 | 2008-03-04 | University Of Southern California | Methods for treating a patient undergoing chemotherapy |
| MXPA02005993A (es) | 1999-12-16 | 2002-10-23 | Univ Southern California | Metodos para tratar y prevenir el dano al tejido epitelial mucoso. |
| WO2001044270A2 (en) | 1999-12-16 | 2001-06-21 | University Of Southern California | Methods for treating and preventing diabetic complications by use of angiotensin-related peptides |
| US6821953B1 (en) | 1999-12-16 | 2004-11-23 | University Of Southern California | Methods for treating and preventing damage to mucosal tissue |
| WO2001098325A1 (en) | 2000-06-19 | 2001-12-27 | University Of Southern California | Methods for treating and preventing alopecia |
| US6747008B1 (en) | 2000-06-19 | 2004-06-08 | University Of Southern California | Methods for treating and preventing alopecia |
| WO2002087504A2 (en) | 2001-05-01 | 2002-11-07 | University Of Southern California | Methods for inhibiting tumor cell proliferation |
| BRPI0105509B8 (pt) | 2001-11-05 | 2021-05-25 | Univ Minas Gerais | formulações do peptídeo angiotensina-(1-7) usando as ciclodextrinas, lipossomas e o polímero plga |
| AU2002364381A1 (en) | 2001-11-23 | 2003-06-10 | Solvay Pharmaceuticals Gmbh | Hypertonia treatment during the acute phase of a cerebrovascular accident |
| DE10306179A1 (de) * | 2003-02-13 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe |
| BRPI0502497A (pt) | 2005-06-28 | 2007-02-06 | Univ Minas Gerais | uso de agonistas e antagonistas do receptor acoplado a proteìna g, mas, como moduladores de atividade apoptótica para o estudo, a prevenção e o tratamento de doenças |
| BRPI0602366B1 (pt) | 2006-04-26 | 2017-12-12 | Universidade Federal De Minas Gerais | Use of agonists of the receptor coupled to protein g, but, in the treatment of metabolic syndrome, its components and their complications |
| WO2008130217A1 (en) | 2006-08-08 | 2008-10-30 | Applied Nanosystems B.V. | Cyclic angiotensin analogs |
| AT506258A1 (de) | 2007-12-18 | 2009-07-15 | Apeiron Biolog Forschungs Und | Behandlung inflammatorischer krankheiten |
| EP2077119A1 (de) | 2007-12-21 | 2009-07-08 | Apeiron Biologics Forschungs- und Entwicklungsgesellschaft M.B.H. | Behandlung von Fibrosen und Lebererkrankungen |
| BRPI0800585B8 (pt) * | 2008-02-13 | 2021-05-25 | Univ Minas Gerais | composições farmacêuticas do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7) e uso do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7) |
| WO2009114461A2 (en) | 2008-03-10 | 2009-09-17 | University Of Southern California | Angiotensin (1-7) dosage forms and uses thereof |
| AT506632A1 (de) | 2008-04-09 | 2009-10-15 | Apeiron Biolog Forschungs Und | Behandlung von tumorerkrankungen |
| EP2163259B1 (en) | 2008-09-12 | 2012-06-13 | Charité-Universitätsmedizin Berlin (Charité) | Use of an Ang-(1-7) receptor agonist in acute lung injury |
| CL2008003736A1 (es) | 2008-12-15 | 2009-05-29 | Univ Pontificia Catolica Chile | Uso de angiotensina (1-9) para preparar un medicamento, util para prevenir, revertir y/o disminuir el remodelado cardiovascular, pulmonar, renal y/o cerebral. |
| RU2011138165A (ru) | 2009-02-17 | 2013-03-27 | Зигнис Байосайенс Гмбх Унд Ко. Кг | Применение g-csf для удлинения периода "терапевтического окна" тромболитического лечения инсульта |
| EP2455388A1 (en) * | 2010-11-23 | 2012-05-23 | LanthioPep B.V. | Novel angiotensin type 2 (AT2) receptor agonists and uses thereof. |
| CN104394878A (zh) | 2012-02-10 | 2015-03-04 | 塔瑞克斯制药有限公司 | 用于治疗周围血管疾病的组合物和方法 |
| US8633158B1 (en) | 2012-10-02 | 2014-01-21 | Tarix Pharmaceuticals Ltd. | Angiotensin in treating brain conditions |
| US9333233B2 (en) | 2014-02-25 | 2016-05-10 | Tarix Pharmaceuticals Ltd. | Methods and compositions for the delayed treatment of stroke |
-
2013
- 2013-01-28 US US13/752,202 patent/US8633158B1/en active Active
- 2013-05-17 US US13/897,051 patent/US9511055B2/en active Active
- 2013-10-02 ES ES13844187.8T patent/ES2689781T3/es active Active
- 2013-10-02 RU RU2015110114A patent/RU2661109C2/ru not_active IP Right Cessation
- 2013-10-02 RU RU2018120387A patent/RU2018120387A/ru not_active Application Discontinuation
- 2013-10-02 KR KR1020157011035A patent/KR20150067228A/ko not_active Ceased
- 2013-10-02 EP EP13844187.8A patent/EP2903605B1/en active Active
- 2013-10-02 CN CN201380062800.XA patent/CN104837485A/zh active Pending
- 2013-10-02 JP JP2015534823A patent/JP6302916B2/ja active Active
- 2013-10-02 AU AU2013327453A patent/AU2013327453A1/en not_active Abandoned
- 2013-10-02 MX MX2015003968A patent/MX366134B/es active IP Right Grant
- 2013-10-02 CA CA2885912A patent/CA2885912A1/en not_active Abandoned
- 2013-10-02 WO PCT/US2013/062969 patent/WO2014055591A1/en not_active Ceased
-
2016
- 2016-10-24 US US15/332,813 patent/US20170258766A1/en not_active Abandoned
-
2018
- 2018-01-12 US US15/870,233 patent/US20190000809A1/en not_active Abandoned
- 2018-03-05 JP JP2018038469A patent/JP6472914B2/ja active Active
- 2018-07-13 AU AU2018205186A patent/AU2018205186B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2661109C2 (ru) | 2018-07-11 |
| ES2689781T3 (es) | 2018-11-15 |
| AU2018205186B2 (en) | 2020-04-09 |
| US20170258766A1 (en) | 2017-09-14 |
| US20140094497A1 (en) | 2014-04-03 |
| JP2018090625A (ja) | 2018-06-14 |
| JP6302916B2 (ja) | 2018-03-28 |
| CN104837485A (zh) | 2015-08-12 |
| EP2903605A4 (en) | 2016-03-23 |
| CA2885912A1 (en) | 2014-04-10 |
| EP2903605B1 (en) | 2018-08-15 |
| US9511055B2 (en) | 2016-12-06 |
| KR20150067228A (ko) | 2015-06-17 |
| AU2018205186A1 (en) | 2018-08-02 |
| AU2013327453A1 (en) | 2015-04-09 |
| EP2903605A1 (en) | 2015-08-12 |
| JP6472914B2 (ja) | 2019-02-20 |
| MX2015003968A (es) | 2016-02-05 |
| US8633158B1 (en) | 2014-01-21 |
| RU2018120387A (ru) | 2018-11-15 |
| JP2015532291A (ja) | 2015-11-09 |
| US20190000809A1 (en) | 2019-01-03 |
| WO2014055591A1 (en) | 2014-04-10 |
| RU2015110114A (ru) | 2016-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |