MX365656B - Nuevas vacunas contra multiples subtipos del virus del dengue. - Google Patents

Nuevas vacunas contra multiples subtipos del virus del dengue.

Info

Publication number
MX365656B
MX365656B MX2015011485A MX2015011485A MX365656B MX 365656 B MX365656 B MX 365656B MX 2015011485 A MX2015011485 A MX 2015011485A MX 2015011485 A MX2015011485 A MX 2015011485A MX 365656 B MX365656 B MX 365656B
Authority
MX
Mexico
Prior art keywords
mammal
dengue
dengue virus
immune response
dna plasmid
Prior art date
Application number
MX2015011485A
Other languages
English (en)
Other versions
MX2015011485A (es
Inventor
Jian Yan
Niranjan Sardesai
David Weiner
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Priority claimed from PCT/US2014/029341 external-priority patent/WO2014144786A1/en
Publication of MX2015011485A publication Critical patent/MX2015011485A/es
Publication of MX365656B publication Critical patent/MX365656B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)

Abstract

La presente invención se refiere a constructos de ácido nucleico capaces de expresar un polipéptido, tal como un dengue de consenso prME que induce una respuesta inmune en un mamífero contra más de un subtipo del virus del dengue, y sus métodos de uso; en forma adicional, existen vacunas de plásmido de ADN capaces de generar en un mamífero una respuesta inmune contra una pluralidad de subtipos del virus del dengue, que comprenden un plásmido de ADN y un excipiente farmacéuticamente aceptable, y sus métodos de uso; el plásmido de ADN es capaz de expresar un antígeno del dengue de consenso en una célula del mamífero en una cantidad efectiva para inducir una respuesta inmune en el mamífero que es reactiva en forma cruzada contra los 4 subtipos de dengue.
MX2015011485A 2013-03-15 2014-03-14 Nuevas vacunas contra multiples subtipos del virus del dengue. MX365656B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361801972P 2013-03-15 2013-03-15
PCT/US2014/029341 WO2014144786A1 (en) 2013-03-15 2014-03-14 Novel vaccines against multiple subtypes of dengue virus

Publications (2)

Publication Number Publication Date
MX2015011485A MX2015011485A (es) 2016-09-23
MX365656B true MX365656B (es) 2019-06-10

Family

ID=54842920

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015011485A MX365656B (es) 2013-03-15 2014-03-14 Nuevas vacunas contra multiples subtipos del virus del dengue.

Country Status (6)

Country Link
EP (1) EP2968394A4 (es)
JP (1) JP6457481B2 (es)
KR (1) KR20160004267A (es)
CN (2) CN110055265A (es)
HK (1) HK1219904A1 (es)
MX (1) MX365656B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110234346B (zh) * 2016-09-19 2024-06-04 宾夕法尼亚大学理事会 新的对抗寨卡病毒的疫苗和用于对抗寨卡病毒的dna抗体构建体的组合

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9592285B2 (en) * 2007-11-12 2017-03-14 The Trustees Of The University Of Pennsylvania Vaccines against multiple subtypes of influenza virus
AU2009210624A1 (en) * 2008-01-11 2009-08-13 Vgx Pharmaceuticals, Inc. Novel vaccines against multiple subtypes of dengue virus
CN101948850A (zh) * 2010-08-13 2011-01-19 中国疾病预防控制中心病毒病预防控制所 登革病毒病毒样颗粒的制备方法及应用
WO2012027473A2 (en) * 2010-08-24 2012-03-01 The University Of North Carolina At Chapel Hill Immunogenic compositions comprising alphavirus vectored dengue virus e protein antigens
EP2621525A4 (en) * 2010-10-01 2015-01-14 Univ Rochester Flavivirus DOMAIN III VACCINE
CN102363751A (zh) * 2011-03-24 2012-02-29 中山大学 登革病毒样颗粒及其制备方法与应用

Also Published As

Publication number Publication date
JP2016515816A (ja) 2016-06-02
CN105246491A (zh) 2016-01-13
EP2968394A1 (en) 2016-01-20
HK1219904A1 (zh) 2017-04-21
EP2968394A4 (en) 2016-04-20
JP6457481B2 (ja) 2019-01-23
CN110055265A (zh) 2019-07-26
MX2015011485A (es) 2016-09-23
CN105246491B (zh) 2019-04-19
KR20160004267A (ko) 2016-01-12

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