EP2968394A4 - Novel vaccines against multiple subtypes of dengue virus - Google Patents

Novel vaccines against multiple subtypes of dengue virus

Info

Publication number
EP2968394A4
EP2968394A4 EP14763126.1A EP14763126A EP2968394A4 EP 2968394 A4 EP2968394 A4 EP 2968394A4 EP 14763126 A EP14763126 A EP 14763126A EP 2968394 A4 EP2968394 A4 EP 2968394A4
Authority
EP
European Patent Office
Prior art keywords
dengue virus
vaccines against
against multiple
multiple subtypes
novel vaccines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14763126.1A
Other languages
German (de)
French (fr)
Other versions
EP2968394A1 (en
Inventor
David Weiner
Jian Yan
Niranjan Sardesai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
Inovio Pharmaceuticals Inc
Original Assignee
University of Pennsylvania Penn
Inovio Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pennsylvania Penn, Inovio Pharmaceuticals Inc filed Critical University of Pennsylvania Penn
Priority claimed from PCT/US2014/029341 external-priority patent/WO2014144786A1/en
Publication of EP2968394A1 publication Critical patent/EP2968394A1/en
Publication of EP2968394A4 publication Critical patent/EP2968394A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
EP14763126.1A 2013-03-15 2014-03-14 Novel vaccines against multiple subtypes of dengue virus Withdrawn EP2968394A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361801972P 2013-03-15 2013-03-15
PCT/US2014/029341 WO2014144786A1 (en) 2013-03-15 2014-03-14 Novel vaccines against multiple subtypes of dengue virus

Publications (2)

Publication Number Publication Date
EP2968394A1 EP2968394A1 (en) 2016-01-20
EP2968394A4 true EP2968394A4 (en) 2016-04-20

Family

ID=54842920

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14763126.1A Withdrawn EP2968394A4 (en) 2013-03-15 2014-03-14 Novel vaccines against multiple subtypes of dengue virus

Country Status (6)

Country Link
EP (1) EP2968394A4 (en)
JP (1) JP6457481B2 (en)
KR (1) KR20160004267A (en)
CN (2) CN110055265A (en)
HK (1) HK1219904A1 (en)
MX (1) MX365656B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11925685B2 (en) * 2016-09-19 2024-03-12 The Trustees Of The University Of Pennsylvania DNA antibody constructs encoding anti-ZIKV envelope antibodies

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009073330A2 (en) * 2007-11-12 2009-06-11 The Trustees Of The University Of Pennsylvania Novel vaccines against multiple subtypes of influenza virus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2685435T3 (en) * 2008-01-11 2018-10-09 Inovio Pharmaceuticals, Inc. New vaccines against multiple subtypes of dengue virus
CN101948850A (en) * 2010-08-13 2011-01-19 中国疾病预防控制中心病毒病预防控制所 Preparation method and application of virus-like particles of dengue viruses
WO2012045063A2 (en) * 2010-10-01 2012-04-05 University Of Rochester Flavivirus domain iii vaccine
CN102363751A (en) * 2011-03-24 2012-02-29 中山大学 Dengue virus (DENV)-like particle as well as preparation method and application thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009073330A2 (en) * 2007-11-12 2009-06-11 The Trustees Of The University Of Pennsylvania Novel vaccines against multiple subtypes of influenza virus

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
APT D ET AL: "Tetravalent neutralizing antibody response against four dengue serotypes by a single chimeric dengue envelope antigen", VACCINE, ELSEVIER LTD, GB, vol. 24, no. 3, 16 January 2006 (2006-01-16), pages 335 - 344, XP028010449, ISSN: 0264-410X, [retrieved on 20060116], DOI: 10.1016/J.VACCINE.2005.07.100 *
DOMINICK J LADDY ET AL: "Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens", PLOS ONE, PUBLIC LIBRARY OF SCIENCE, US, vol. 3, no. 6, 1 June 2008 (2008-06-01) - 1 June 2008 (2008-06-01), pages 1 - 8, XP008132555, ISSN: 1932-6203, DOI: 10.1371/JOURNAL.PONE.0002517 *
LADDY ET AL: "Immunogenicity of novel consensus-based DNA vaccines against avian influenza", VACCINE, ELSEVIER LTD, GB, vol. 25, no. 16, 29 March 2007 (2007-03-29), pages 2984 - 2989, XP022004278, ISSN: 0264-410X, DOI: 10.1016/J.VACCINE.2007.01.063 *
NIRANJAN Y SARDESAI ET AL: "Electroporation delivery of DNA vaccines: prospects for success", CURRENT OPINION IN IMMUNOLOGY, vol. 23, no. 3, 1 June 2008 (2008-06-01), pages 421 - 429, XP028223967, ISSN: 0952-7915, [retrieved on 20110330], DOI: 10.1016/J.COI.2011.03.008 *
RAMANATHAN M P ET AL: "Coimmunization with an optimized IL15 plasmid adjuvant enhances humoral immunity via stimulating B cells induced by genetically engineered DNA vaccines expressing consensus JEV and WNV E DIII", VACCINE, ELSEVIER LTD, GB, vol. 27, no. 32, 9 July 2009 (2009-07-09), pages 4370 - 4380, XP026210587, ISSN: 0264-410X, [retrieved on 20090306], DOI: 10.1016/J.VACCINE.2009.01.137 *
RAMANATHAN M P ET AL: "Development of a novel DNA SynCon(TM) tetravalent dengue vaccine that elicits immune responses against four serotypes", VACCINE, ELSEVIER LTD, GB, vol. 27, no. 46, 30 October 2009 (2009-10-30), pages 6444 - 6453, XP026704481, ISSN: 0264-410X, [retrieved on 20090704], DOI: 10.1016/J.VACCINE.2009.06.061 *
RAVIPRAKASH K ET AL: "A chimeric tetravalent dengue DNA vaccine elicits neutralizing antibody to all four virus serotypes in rhesus macaques", VIROLOGY, ELSEVIER, AMSTERDAM, NL, vol. 353, no. 1, 15 September 2006 (2006-09-15), pages 166 - 173, XP024896386, ISSN: 0042-6822, [retrieved on 20060915], DOI: 10.1016/J.VIROL.2006.05.005 *
See also references of WO2014144786A1 *

Also Published As

Publication number Publication date
CN105246491A (en) 2016-01-13
CN105246491B (en) 2019-04-19
JP2016515816A (en) 2016-06-02
CN110055265A (en) 2019-07-26
MX365656B (en) 2019-06-10
JP6457481B2 (en) 2019-01-23
KR20160004267A (en) 2016-01-12
EP2968394A1 (en) 2016-01-20
HK1219904A1 (en) 2017-04-21
MX2015011485A (en) 2016-09-23

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