MX364929B - Derivados de la 5-amino-quinolina-8-carboxamida como agonistas del receptor 5-ht4. - Google Patents
Derivados de la 5-amino-quinolina-8-carboxamida como agonistas del receptor 5-ht4.Info
- Publication number
- MX364929B MX364929B MX2015012350A MX2015012350A MX364929B MX 364929 B MX364929 B MX 364929B MX 2015012350 A MX2015012350 A MX 2015012350A MX 2015012350 A MX2015012350 A MX 2015012350A MX 364929 B MX364929 B MX 364929B
- Authority
- MX
- Mexico
- Prior art keywords
- agonists
- receptor
- carboxamide
- quinoline
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57505—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the blood, e.g. leukaemia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/82—Translation products from oncogenes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2013/000639 WO2014147636A1 (en) | 2013-03-20 | 2013-10-18 | 5-amino-quinoline-8-carboxamide derivatives as 5-ht4 receptor agonists |
| IN1199CH2013 IN2013CH01199A (enExample) | 2013-03-20 | 2013-10-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015012350A MX2015012350A (es) | 2016-05-09 |
| MX364929B true MX364929B (es) | 2019-05-14 |
Family
ID=54325095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015012350A MX364929B (es) | 2013-03-20 | 2013-10-18 | Derivados de la 5-amino-quinolina-8-carboxamida como agonistas del receptor 5-ht4. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9790211B2 (enExample) |
| EP (1) | EP2976337B1 (enExample) |
| JP (1) | JP6185650B2 (enExample) |
| KR (1) | KR101815307B1 (enExample) |
| CN (1) | CN105164119B (enExample) |
| AP (1) | AP2015008742A0 (enExample) |
| AU (1) | AU2013382944B2 (enExample) |
| BR (1) | BR112015024060A2 (enExample) |
| CA (1) | CA2907620C (enExample) |
| DK (1) | DK2976337T3 (enExample) |
| EA (1) | EA029365B1 (enExample) |
| ES (1) | ES2674993T3 (enExample) |
| IN (1) | IN2013CH01199A (enExample) |
| MX (1) | MX364929B (enExample) |
| NZ (1) | NZ712369A (enExample) |
| SG (1) | SG11201507763RA (enExample) |
| WO (1) | WO2014147636A1 (enExample) |
| ZA (1) | ZA201506804B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107406434B (zh) * | 2015-02-13 | 2020-09-11 | 苏文生命科学有限公司 | 作为5-ht4受体激动剂的酰胺化合物 |
| CN109444301A (zh) * | 2018-12-18 | 2019-03-08 | 江苏省中医院 | 一种测定血浆中普芦卡必利浓度的方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5708174A (en) | 1992-03-12 | 1998-01-13 | Smithkline Beecham P.L.C. | Heterocyclic-esters or -amides used as 5-HT4 receptor antagonists |
| US5705498A (en) | 1992-11-05 | 1998-01-06 | Smithkline Beecham Plc. | Piperidine derivatives as 5-HT4 receptor antagonists |
| FR2756564B1 (fr) * | 1996-12-04 | 2004-05-14 | Synthelabo | Derives d'acide quinoleine-8-carboxylique, leur preparation et leur application en therapeutique |
| WO2001095903A1 (en) * | 2000-06-15 | 2001-12-20 | Respiratorius Ab | 5-ht3 receptor antagonists for treatment of disorders involving airway constriction |
| JP4688799B2 (ja) * | 2003-06-19 | 2011-05-25 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ５ｈｔ４−拮抗性４−（アミノメチル）−ピペリジンベンズアミド |
| ES2338882T3 (es) | 2003-11-24 | 2010-05-13 | Pfizer, Inc. | Compuestos de acido quinolona-carboxilico que tienen actividad agonista del receptor 5-ht4. |
| WO2005061483A2 (en) | 2003-12-23 | 2005-07-07 | Bio-Medisinsk Innovasjon As | Modulators of peripheral 5-ht receptors |
| WO2005092882A1 (en) * | 2004-03-01 | 2005-10-06 | Pfizer Japan, Inc. | 4-amino-5-halogeno-benzamide derivatives as 5-ht4 receptor agonists for the treatment of gastrointestinal, cns, neurological and cardiovascular disorders |
| US8816090B2 (en) | 2005-02-25 | 2014-08-26 | Pfizer Inc. | Benzisoxazole derivatives |
| WO2007010390A1 (en) | 2005-07-22 | 2007-01-25 | Pfizer Japan Inc. | Indazolecarboxamide derivatives as 5ht4 receptor agonists |
| GB0525661D0 (en) * | 2005-12-16 | 2006-01-25 | Glaxo Group Ltd | Novel compounds |
| CN107260736A (zh) | 2010-02-12 | 2017-10-20 | 株式会社ＡｓｋＡｔ | 用于治疗痴呆的5‑ht4受体激动剂 |
| KR20120123089A (ko) | 2010-02-16 | 2012-11-07 | 화이자 인코포레이티드 | 5-ＨＴ₄ 수용체의 부분 효능제인 (Ｒ)-4-((4-((4-(테트라히드로푸란-3-일옥시)벤조［ｄ］이속사졸-3-일옥시)메틸)피페리딘-1-일)메틸)테트라히드로-2Ｈ-피란-4-올 |
-
2013
- 2013-10-18 DK DK13811624.9T patent/DK2976337T3/en active
- 2013-10-18 NZ NZ712369A patent/NZ712369A/en not_active IP Right Cessation
- 2013-10-18 CA CA2907620A patent/CA2907620C/en not_active Expired - Fee Related
- 2013-10-18 CN CN201380074877.9A patent/CN105164119B/zh not_active Expired - Fee Related
- 2013-10-18 AU AU2013382944A patent/AU2013382944B2/en not_active Ceased
- 2013-10-18 EP EP13811624.9A patent/EP2976337B1/en active Active
- 2013-10-18 KR KR1020157030158A patent/KR101815307B1/ko not_active Expired - Fee Related
- 2013-10-18 JP JP2016504852A patent/JP6185650B2/ja not_active Expired - Fee Related
- 2013-10-18 AP AP2015008742A patent/AP2015008742A0/xx unknown
- 2013-10-18 IN IN1199CH2013 patent/IN2013CH01199A/en unknown
- 2013-10-18 WO PCT/IN2013/000639 patent/WO2014147636A1/en not_active Ceased
- 2013-10-18 US US14/777,925 patent/US9790211B2/en not_active Expired - Fee Related
- 2013-10-18 BR BR112015024060A patent/BR112015024060A2/pt not_active IP Right Cessation
- 2013-10-18 ES ES13811624.9T patent/ES2674993T3/es active Active
- 2013-10-18 EA EA201591844A patent/EA029365B1/ru not_active IP Right Cessation
- 2013-10-18 MX MX2015012350A patent/MX364929B/es active IP Right Grant
- 2013-10-18 SG SG11201507763RA patent/SG11201507763RA/en unknown
-
2015
- 2015-09-14 ZA ZA2015/06804A patent/ZA201506804B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP6185650B2 (ja) | 2017-08-23 |
| AU2013382944A1 (en) | 2015-10-08 |
| CN105164119B (zh) | 2017-12-08 |
| EP2976337B1 (en) | 2018-05-02 |
| EP2976337A1 (en) | 2016-01-27 |
| JP2016516089A (ja) | 2016-06-02 |
| US20160280694A1 (en) | 2016-09-29 |
| EA201591844A1 (ru) | 2016-08-31 |
| SG11201507763RA (en) | 2015-10-29 |
| CA2907620A1 (en) | 2014-09-25 |
| IN2013CH01199A (enExample) | 2015-08-14 |
| NZ712369A (en) | 2016-11-25 |
| CA2907620C (en) | 2018-03-13 |
| KR20160004274A (ko) | 2016-01-12 |
| DK2976337T3 (en) | 2018-07-16 |
| AP2015008742A0 (en) | 2015-09-30 |
| EA029365B1 (ru) | 2018-03-30 |
| ZA201506804B (en) | 2016-07-27 |
| ES2674993T3 (es) | 2018-07-05 |
| MX2015012350A (es) | 2016-05-09 |
| AU2013382944B2 (en) | 2016-08-04 |
| WO2014147636A8 (en) | 2014-12-04 |
| HK1217483A1 (zh) | 2017-01-13 |
| WO2014147636A1 (en) | 2014-09-25 |
| CN105164119A (zh) | 2015-12-16 |
| KR101815307B1 (ko) | 2018-01-04 |
| US9790211B2 (en) | 2017-10-17 |
| BR112015024060A2 (pt) | 2017-07-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |