MX364929B - Derivados de la 5-amino-quinolina-8-carboxamida como agonistas del receptor 5-ht4. - Google Patents
Derivados de la 5-amino-quinolina-8-carboxamida como agonistas del receptor 5-ht4.Info
- Publication number
- MX364929B MX364929B MX2015012350A MX2015012350A MX364929B MX 364929 B MX364929 B MX 364929B MX 2015012350 A MX2015012350 A MX 2015012350A MX 2015012350 A MX2015012350 A MX 2015012350A MX 364929 B MX364929 B MX 364929B
- Authority
- MX
- Mexico
- Prior art keywords
- agonists
- receptor
- carboxamide
- quinoline
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57505—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the blood, e.g. leukaemia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/82—Translation products from oncogenes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1199CH2013 IN2013CH01199A (enExample) | 2013-03-20 | 2013-10-18 | |
| PCT/IN2013/000639 WO2014147636A1 (en) | 2013-03-20 | 2013-10-18 | 5-amino-quinoline-8-carboxamide derivatives as 5-ht4 receptor agonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015012350A MX2015012350A (es) | 2016-05-09 |
| MX364929B true MX364929B (es) | 2019-05-14 |
Family
ID=54325095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015012350A MX364929B (es) | 2013-03-20 | 2013-10-18 | Derivados de la 5-amino-quinolina-8-carboxamida como agonistas del receptor 5-ht4. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9790211B2 (enExample) |
| EP (1) | EP2976337B1 (enExample) |
| JP (1) | JP6185650B2 (enExample) |
| KR (1) | KR101815307B1 (enExample) |
| CN (1) | CN105164119B (enExample) |
| AP (1) | AP2015008742A0 (enExample) |
| AU (1) | AU2013382944B2 (enExample) |
| BR (1) | BR112015024060A2 (enExample) |
| CA (1) | CA2907620C (enExample) |
| DK (1) | DK2976337T3 (enExample) |
| EA (1) | EA029365B1 (enExample) |
| ES (1) | ES2674993T3 (enExample) |
| IN (1) | IN2013CH01199A (enExample) |
| MX (1) | MX364929B (enExample) |
| NZ (1) | NZ712369A (enExample) |
| SG (1) | SG11201507763RA (enExample) |
| WO (1) | WO2014147636A1 (enExample) |
| ZA (1) | ZA201506804B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ734400A (en) * | 2015-02-13 | 2018-03-23 | Suven Life Sciences Ltd | Amide compounds as 5-ht4 receptor agonists |
| CN109444301A (zh) * | 2018-12-18 | 2019-03-08 | 江苏省中医院 | 一种测定血浆中普芦卡必利浓度的方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994008994A1 (en) * | 1992-10-13 | 1994-04-28 | Smithkline Beecham Plc | Heterocyclic -esters or -amides used as 5-ht4 receptor antagonists |
| WO1994010174A1 (en) | 1992-11-05 | 1994-05-11 | Smithkline Beecham Plc | Piperidine derivatives as 5-ht4 receptor antagonists |
| FR2756564B1 (fr) * | 1996-12-04 | 2004-05-14 | Synthelabo | Derives d'acide quinoleine-8-carboxylique, leur preparation et leur application en therapeutique |
| WO2001095903A1 (en) * | 2000-06-15 | 2001-12-20 | Respiratorius Ab | 5-ht3 receptor antagonists for treatment of disorders involving airway constriction |
| AU2004254193B2 (en) * | 2003-06-19 | 2010-02-18 | Janssen Pharmaceutica N.V. | 5ht4-antagonistic 4-(aminomethyl)-piperidine benzamides |
| CA2545092C (en) | 2003-11-24 | 2010-08-17 | Pfizer Inc. | Quinolonecarboxylic acid compounds having 5-ht4 receptor agonistic activity |
| DK1701951T3 (da) * | 2003-12-23 | 2010-06-07 | Serodus As | Modulatorer af perifere 5-HT receptorer |
| WO2005092882A1 (en) * | 2004-03-01 | 2005-10-06 | Pfizer Japan, Inc. | 4-amino-5-halogeno-benzamide derivatives as 5-ht4 receptor agonists for the treatment of gastrointestinal, cns, neurological and cardiovascular disorders |
| US8816090B2 (en) | 2005-02-25 | 2014-08-26 | Pfizer Inc. | Benzisoxazole derivatives |
| ATE449092T1 (de) | 2005-07-22 | 2009-12-15 | Pfizer | Indazolcarbonsäureamidderivate als agonisten des 5ht4-rezeptors |
| GB0525661D0 (en) * | 2005-12-16 | 2006-01-25 | Glaxo Group Ltd | Novel compounds |
| RU2569733C2 (ru) * | 2010-02-12 | 2015-11-27 | Раквалиа Фарма Инк. | Агонисты 5-нт4-рецепторов для лечения деменции |
| JP2013519722A (ja) | 2010-02-16 | 2013-05-30 | ファイザー・インク | （ｒ）−４−（（４−（（４−（テトラヒドロフラン−３−イルオキシ）ベンゾ［ｄ］イソオキサゾール−３−イルオキシ）メチル）ピペリジン−１−イル）メチル）テトラヒドロ−２ｈ−ピラン−４−オール、５−ｈｔ４受容体の部分アゴニスト |
-
2013
- 2013-10-18 DK DK13811624.9T patent/DK2976337T3/en active
- 2013-10-18 AU AU2013382944A patent/AU2013382944B2/en not_active Ceased
- 2013-10-18 US US14/777,925 patent/US9790211B2/en not_active Expired - Fee Related
- 2013-10-18 WO PCT/IN2013/000639 patent/WO2014147636A1/en not_active Ceased
- 2013-10-18 NZ NZ712369A patent/NZ712369A/en not_active IP Right Cessation
- 2013-10-18 SG SG11201507763RA patent/SG11201507763RA/en unknown
- 2013-10-18 MX MX2015012350A patent/MX364929B/es active IP Right Grant
- 2013-10-18 ES ES13811624.9T patent/ES2674993T3/es active Active
- 2013-10-18 CN CN201380074877.9A patent/CN105164119B/zh not_active Expired - Fee Related
- 2013-10-18 JP JP2016504852A patent/JP6185650B2/ja not_active Expired - Fee Related
- 2013-10-18 KR KR1020157030158A patent/KR101815307B1/ko not_active Expired - Fee Related
- 2013-10-18 BR BR112015024060A patent/BR112015024060A2/pt not_active IP Right Cessation
- 2013-10-18 AP AP2015008742A patent/AP2015008742A0/xx unknown
- 2013-10-18 CA CA2907620A patent/CA2907620C/en not_active Expired - Fee Related
- 2013-10-18 EP EP13811624.9A patent/EP2976337B1/en active Active
- 2013-10-18 IN IN1199CH2013 patent/IN2013CH01199A/en unknown
- 2013-10-18 EA EA201591844A patent/EA029365B1/ru not_active IP Right Cessation
-
2015
- 2015-09-14 ZA ZA2015/06804A patent/ZA201506804B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2013382944A1 (en) | 2015-10-08 |
| BR112015024060A2 (pt) | 2017-07-18 |
| CA2907620A1 (en) | 2014-09-25 |
| WO2014147636A8 (en) | 2014-12-04 |
| JP2016516089A (ja) | 2016-06-02 |
| KR20160004274A (ko) | 2016-01-12 |
| EP2976337B1 (en) | 2018-05-02 |
| IN2013CH01199A (enExample) | 2015-08-14 |
| HK1217483A1 (zh) | 2017-01-13 |
| EA029365B1 (ru) | 2018-03-30 |
| KR101815307B1 (ko) | 2018-01-04 |
| US9790211B2 (en) | 2017-10-17 |
| WO2014147636A1 (en) | 2014-09-25 |
| DK2976337T3 (en) | 2018-07-16 |
| AP2015008742A0 (en) | 2015-09-30 |
| NZ712369A (en) | 2016-11-25 |
| MX2015012350A (es) | 2016-05-09 |
| US20160280694A1 (en) | 2016-09-29 |
| ES2674993T3 (es) | 2018-07-05 |
| ZA201506804B (en) | 2016-07-27 |
| CA2907620C (en) | 2018-03-13 |
| JP6185650B2 (ja) | 2017-08-23 |
| EA201591844A1 (ru) | 2016-08-31 |
| EP2976337A1 (en) | 2016-01-27 |
| SG11201507763RA (en) | 2015-10-29 |
| AU2013382944B2 (en) | 2016-08-04 |
| CN105164119B (zh) | 2017-12-08 |
| CN105164119A (zh) | 2015-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |