MX361757B - Nueva composicion farmaceutica resistente al abuso para el tratamiento de la dependencia de opioides. - Google Patents

Nueva composicion farmaceutica resistente al abuso para el tratamiento de la dependencia de opioides.

Info

Publication number
MX361757B
MX361757B MX2014002556A MX2014002556A MX361757B MX 361757 B MX361757 B MX 361757B MX 2014002556 A MX2014002556 A MX 2014002556A MX 2014002556 A MX2014002556 A MX 2014002556A MX 361757 B MX361757 B MX 361757B
Authority
MX
Mexico
Prior art keywords
treatment
pharmaceutical composition
particles
opioid dependence
resistant pharmaceutical
Prior art date
Application number
MX2014002556A
Other languages
English (en)
Other versions
MX2014002556A (es
Inventor
Andreas Fischer
Original Assignee
Orexo Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47046639&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX361757(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orexo Ab filed Critical Orexo Ab
Publication of MX2014002556A publication Critical patent/MX2014002556A/es
Publication of MX361757B publication Critical patent/MX361757B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4748—Quinolines; Isoquinolines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Abstract

Se proporcionan composiciones farmacéuticas para el tratamiento de, por ejemplo, la dependencia de opioides, que comprende micropartículas de una cantidad farmacológicamente eficaz de buprenorfina o una sal farmaceúticamente aceptable de la misma, en mezcla asociativa con partículas que comprenden un ácido débil o partículas que comprenden materiales formadores de tampón débilmente ácido. La composición puede comprender además un disgregante y/o partículas de una cantidad farmacológicamente eficaz de naloxona, o una sal farmacéuticamente aceptable de la misma. Las composiciones son útiles en el tratamiento de la dependencia/adicción de/a los opioides y/o el dolor.
MX2014002556A 2011-09-19 2012-09-18 Nueva composicion farmaceutica resistente al abuso para el tratamiento de la dependencia de opioides. MX361757B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161536180P 2011-09-19 2011-09-19
PCT/GB2012/052303 WO2013041851A1 (en) 2011-09-19 2012-09-18 New abuse-resistant pharmaceutical composition for the treatment of opioid dependence

Publications (2)

Publication Number Publication Date
MX2014002556A MX2014002556A (es) 2014-10-06
MX361757B true MX361757B (es) 2018-12-13

Family

ID=47046639

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014002556A MX361757B (es) 2011-09-19 2012-09-18 Nueva composicion farmaceutica resistente al abuso para el tratamiento de la dependencia de opioides.

Country Status (31)

Country Link
US (15) US8940330B2 (es)
EP (3) EP2706986B1 (es)
JP (2) JP6210988B2 (es)
KR (1) KR102078044B1 (es)
CN (1) CN103813785B (es)
AU (1) AU2012311293B2 (es)
BR (1) BR112014006356B1 (es)
CA (1) CA2834327C (es)
CL (1) CL2014000575A1 (es)
CO (1) CO6960541A2 (es)
CY (2) CY1116270T1 (es)
DK (2) DK2915525T3 (es)
EA (1) EA029507B1 (es)
ES (2) ES2887104T3 (es)
HK (2) HK1193568A1 (es)
HR (2) HRP20211539T1 (es)
HU (1) HUE056309T2 (es)
IL (1) IL230528B (es)
LT (1) LT2915525T (es)
ME (1) ME02153B (es)
MX (1) MX361757B (es)
MY (1) MY185284A (es)
PE (1) PE20141198A1 (es)
PL (2) PL2706986T3 (es)
PT (2) PT2706986E (es)
RS (2) RS53995B1 (es)
SG (1) SG2014009401A (es)
SI (2) SI2706986T1 (es)
SM (1) SMT201500126B (es)
WO (1) WO2013041851A1 (es)
ZA (1) ZA201400501B (es)

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