GB1428361A - Safeguarded medicinal compositions - Google Patents

Safeguarded medicinal compositions

Info

Publication number
GB1428361A
GB1428361A GB702672A GB702672A GB1428361A GB 1428361 A GB1428361 A GB 1428361A GB 702672 A GB702672 A GB 702672A GB 702672 A GB702672 A GB 702672A GB 1428361 A GB1428361 A GB 1428361A
Authority
GB
Grant status
Application
Patent type
Prior art keywords
drug
emetic
feb
enteric
pellets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB702672A
Original Assignee
Grant A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Abstract

1428361 Safeguarded medicaments A GRANT 15 Feb 1973 [15 Feb 1972] 7026/72 Heading A5B Pharmaceutical compositions in the form of capsules and slugs comprise a drug (e.g. aspirin or a barbiturate) and an emetic, the quantity of the latter being sufficient to produce emesis When the drug is administered at overdose levels, the availability of the drug being delayed relative to that of the emetic by a coating thereon of a third substance which delays release of the drug but not the emetic. Specific reference is made to a capsule filling comprising pellets of enteric-coated drug and non- enteric pellets containing emetic of similar appearance. Suitable emetics are emetine and cephaelin drugs, ipecacuanha extract, mustard, ZnSO4 and apomorphine.
GB702672A 1972-02-15 1972-02-15 Safeguarded medicinal compositions Expired GB1428361A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB702672A GB1428361A (en) 1972-02-15 1972-02-15 Safeguarded medicinal compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB702672A GB1428361A (en) 1972-02-15 1972-02-15 Safeguarded medicinal compositions

Publications (1)

Publication Number Publication Date
GB1428361A true true GB1428361A (en) 1976-03-17

Family

ID=9825235

Family Applications (1)

Application Number Title Priority Date Filing Date
GB702672A Expired GB1428361A (en) 1972-02-15 1972-02-15 Safeguarded medicinal compositions

Country Status (1)

Country Link
GB (1) GB1428361A (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2162061A (en) * 1984-05-03 1986-01-29 Bibhuti B Bardhan Controlled time release therapeutic composition having means for counteracting overdosage
WO2004054562A1 (en) * 2002-12-16 2004-07-01 Pharmaquest Ltd. Method for preventing abuse of methylphenidate
EP1581188A1 (en) * 2003-01-10 2005-10-05 Mutual Pharmaceutical Company, Inc. Pharmaceutical safety dosage forms
EP1893183A1 (en) * 2005-06-13 2008-03-05 Paul Rosenberg Emetic embedded capsule
WO2010081920A1 (en) * 2009-01-15 2010-07-22 Valle Raquel Miriam Rodriguez Incorporation of an emetic in drugs as a safety system in respect of possible overdoses, particularly in drugs acting on the central nervous system such as benzodiazepine and derivatives, barbiturates... and drugs for paediatric use
US7981439B2 (en) * 2003-11-26 2011-07-19 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of drugs susceptible to abuse and dosage forms thereof
US8901113B2 (en) 2009-09-30 2014-12-02 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse
US8940330B2 (en) 2011-09-19 2015-01-27 Orexo Ab Abuse-resistant pharmaceutical composition for the treatment of opioid dependence
US9060950B2 (en) 2005-06-13 2015-06-23 Paul H. Rosenberg, Proximate Concepts, LLC. Emetic embedded capsule
US9101636B2 (en) 2012-11-30 2015-08-11 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2162061A (en) * 1984-05-03 1986-01-29 Bibhuti B Bardhan Controlled time release therapeutic composition having means for counteracting overdosage
WO2004054562A1 (en) * 2002-12-16 2004-07-01 Pharmaquest Ltd. Method for preventing abuse of methylphenidate
EP1581188A1 (en) * 2003-01-10 2005-10-05 Mutual Pharmaceutical Company, Inc. Pharmaceutical safety dosage forms
EP1581188A4 (en) * 2003-01-10 2006-04-05 Mutual Pharmaceutical Co Pharmaceutical safety dosage forms
US7524515B2 (en) 2003-01-10 2009-04-28 Mutual Pharmaceuticals, Inc. Pharmaceutical safety dosage forms
US7919120B2 (en) 2003-01-10 2011-04-05 Mutual Pharmaceuticals, Inc. Pharmaceutical safety dosage forms
US8822489B2 (en) 2003-11-26 2014-09-02 Acura Pharmaceuticals Abuse deterrent compositions and methods of making same
US7981439B2 (en) * 2003-11-26 2011-07-19 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of drugs susceptible to abuse and dosage forms thereof
US8637540B2 (en) 2003-11-26 2014-01-28 Acura Pharmaceuticals Compositions for deterring abuse of opioid containing dosage forms
US9492443B2 (en) 2003-11-26 2016-11-15 Acura Pharmaceuticals, Inc. Abuse deterrent compositions and methods of making same
EP1893183A4 (en) * 2005-06-13 2010-08-18 Paul Rosenberg Emetic embedded capsule
EP1893183A1 (en) * 2005-06-13 2008-03-05 Paul Rosenberg Emetic embedded capsule
US9060950B2 (en) 2005-06-13 2015-06-23 Paul H. Rosenberg, Proximate Concepts, LLC. Emetic embedded capsule
WO2010081920A1 (en) * 2009-01-15 2010-07-22 Valle Raquel Miriam Rodriguez Incorporation of an emetic in drugs as a safety system in respect of possible overdoses, particularly in drugs acting on the central nervous system such as benzodiazepine and derivatives, barbiturates... and drugs for paediatric use
US8901113B2 (en) 2009-09-30 2014-12-02 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse
US9259421B2 (en) 2011-09-19 2016-02-16 Orexo Ab Abuse-resistant pharmaceutical composition for the treatment of opioid dependence
US9439900B2 (en) 2011-09-19 2016-09-13 Orexo Ab Abuse-resistant pharmaceutical composition for the treatment of opioid dependence
US8940330B2 (en) 2011-09-19 2015-01-27 Orexo Ab Abuse-resistant pharmaceutical composition for the treatment of opioid dependence
US9101636B2 (en) 2012-11-30 2015-08-11 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient
US9320796B2 (en) 2012-11-30 2016-04-26 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee