MX360391B - Composiciones liposomales combinadas para terapia contra el cancer. - Google Patents
Composiciones liposomales combinadas para terapia contra el cancer.Info
- Publication number
- MX360391B MX360391B MX2014004960A MX2014004960A MX360391B MX 360391 B MX360391 B MX 360391B MX 2014004960 A MX2014004960 A MX 2014004960A MX 2014004960 A MX2014004960 A MX 2014004960A MX 360391 B MX360391 B MX 360391B
- Authority
- MX
- Mexico
- Prior art keywords
- combinational
- cancer therapy
- liposome compositions
- liposome
- therapeutic
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title 1
- 238000011275 oncology therapy Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161553786P | 2011-10-31 | 2011-10-31 | |
| PCT/US2012/062635 WO2013066903A1 (en) | 2011-10-31 | 2012-10-31 | Combinational liposome compositions for cancer therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014004960A MX2014004960A (es) | 2014-06-05 |
| MX360391B true MX360391B (es) | 2018-10-31 |
Family
ID=47146747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014004960A MX360391B (es) | 2011-10-31 | 2012-10-31 | Composiciones liposomales combinadas para terapia contra el cancer. |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US9370489B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3424564A1 (cg-RX-API-DMAC7.html) |
| JP (4) | JP6143767B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20140097215A (cg-RX-API-DMAC7.html) |
| CN (1) | CN104023793B (cg-RX-API-DMAC7.html) |
| BR (1) | BR112014010291A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2852564A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2694154T3 (cg-RX-API-DMAC7.html) |
| IL (2) | IL232344B (cg-RX-API-DMAC7.html) |
| MX (1) | MX360391B (cg-RX-API-DMAC7.html) |
| RU (1) | RU2640934C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013066903A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (62)
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| CA2768444A1 (en) * | 2009-07-17 | 2011-01-20 | Rigshospitalet | Loading technique for preparing radionuclide and ionophore containing liposomes in which the ionophore is 2-hydroxyquionoline (carbostyril) or structurally related 2-hydroxyquinolines |
| EP2600901B1 (en) | 2010-08-06 | 2019-03-27 | ModernaTX, Inc. | A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof |
| MX2013003681A (es) | 2010-10-01 | 2013-11-20 | Moderna Therapeutics Inc | Ácidos nucleicos manipulados y métodos de uso de los mismos. |
| WO2012135805A2 (en) | 2011-03-31 | 2012-10-04 | modeRNA Therapeutics | Delivery and formulation of engineered nucleic acids |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| US9428535B2 (en) | 2011-10-03 | 2016-08-30 | Moderna Therapeutics, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
| SMT202200355T1 (it) | 2011-12-16 | 2022-11-18 | Modernatx Inc | Composizioni di mrna modificato |
| EP2834260A4 (en) | 2012-04-02 | 2016-08-10 | Moderna Therapeutics Inc | MODIFIED POLYNUCLEOTIDES FOR THE PREPARATION OF MEMBRANE PROTEINS |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| US10501512B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| EP2922554B1 (en) | 2012-11-26 | 2022-02-23 | ModernaTX, Inc. | Terminally modified rna |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| PL4332576T3 (pl) | 2013-03-15 | 2025-09-08 | Translate Bio, Inc. | Synergistyczne wzmocnienie dostarczania kwasów nukleinowych poprzez formulacje zmieszane |
| JP2014227338A (ja) * | 2013-05-17 | 2014-12-08 | キヤノン株式会社 | インドシアニングリーン含有粒子およびその製造方法 |
| CA2938626A1 (en) | 2013-07-26 | 2015-01-29 | John Rothman | Compositions to improve the therapeutic benefit of bisantrene |
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| CN106474057A (zh) * | 2016-12-02 | 2017-03-08 | 中国药科大学 | 一种奥沙利铂热敏长循环脂质体的蔗糖溶液制剂及其制备方法 |
| CN110381922A (zh) * | 2017-01-18 | 2019-10-25 | 淡马锡生命科学研究院有限公司 | 超稳定脂质体增加对有丝分裂细胞的靶向作用 |
| RS63953B1 (sr) | 2017-03-15 | 2023-02-28 | Modernatx Inc | Jedinjenje i kompozicije za intracelularnu isporuku terapeutskih sredstava |
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| US10925831B2 (en) * | 2017-08-28 | 2021-02-23 | Wake Forest University | Liposomal formulations of platinum-acridine anticancer agents and methods thereof |
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| US11110060B2 (en) * | 2017-10-25 | 2021-09-07 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for delivering pharmaceutical agents |
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| EP3811949B1 (en) | 2018-06-20 | 2024-07-03 | FUJIFILM Corporation | Combined medicine comprising gemcitabine-encapsulated liposome composition and immune checkpoint blockade |
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| JP7253735B2 (ja) | 2019-07-02 | 2023-04-07 | パナソニックIpマネジメント株式会社 | 通過可否判定装置、通過管理システム、通過可否判定方法、及び、コンピュータプログラム |
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| CN110571005B (zh) * | 2019-09-27 | 2021-01-01 | 广西科技大学 | 一种固定化金属离子-磁性脂质体及其制备方法和应用 |
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| US20240229154A9 (en) | 2021-02-12 | 2024-07-11 | Institut National de la Santé et de la Recherche Médicale | Method for prognosis and treating a patient suffering from cancer |
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| WO2007049279A2 (en) * | 2005-10-26 | 2007-05-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | A liposomal combination and uses thereof |
-
2012
- 2012-10-31 EP EP18189596.2A patent/EP3424564A1/en not_active Withdrawn
- 2012-10-31 WO PCT/US2012/062635 patent/WO2013066903A1/en not_active Ceased
- 2012-10-31 EP EP12783805.0A patent/EP2773426B1/en not_active Not-in-force
- 2012-10-31 CN CN201280064482.6A patent/CN104023793B/zh not_active Expired - Fee Related
- 2012-10-31 MX MX2014004960A patent/MX360391B/es active IP Right Grant
- 2012-10-31 BR BR112014010291A patent/BR112014010291A2/pt not_active Application Discontinuation
- 2012-10-31 CA CA2852564A patent/CA2852564A1/en not_active Abandoned
- 2012-10-31 RU RU2014120216A patent/RU2640934C2/ru not_active IP Right Cessation
- 2012-10-31 ES ES12783805.0T patent/ES2694154T3/es active Active
- 2012-10-31 US US13/664,457 patent/US9370489B2/en not_active Expired - Fee Related
- 2012-10-31 JP JP2014539143A patent/JP6143767B2/ja not_active Expired - Fee Related
- 2012-10-31 KR KR1020147014027A patent/KR20140097215A/ko not_active Ceased
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2014
- 2014-04-29 IL IL232344A patent/IL232344B/en active IP Right Grant
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2016
- 2016-05-23 US US15/162,072 patent/US9717686B2/en not_active Expired - Fee Related
-
2017
- 2017-03-09 JP JP2017044663A patent/JP6549172B2/ja not_active Expired - Fee Related
- 2017-07-28 US US15/663,472 patent/US10213385B2/en not_active Expired - Fee Related
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2018
- 2018-04-16 IL IL258740A patent/IL258740B/en unknown
- 2018-11-21 JP JP2018218127A patent/JP2019023243A/ja active Pending
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2019
- 2019-02-19 US US16/279,977 patent/US20190175505A1/en not_active Abandoned
- 2019-05-08 JP JP2019088222A patent/JP2019123753A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2017101085A (ja) | 2017-06-08 |
| WO2013066903A1 (en) | 2013-05-10 |
| RU2640934C2 (ru) | 2018-01-12 |
| CN104023793B (zh) | 2017-11-24 |
| ES2694154T3 (es) | 2018-12-18 |
| CA2852564A1 (en) | 2013-05-10 |
| MX2014004960A (es) | 2014-06-05 |
| IL258740A (en) | 2018-06-28 |
| KR20140097215A (ko) | 2014-08-06 |
| JP2014532665A (ja) | 2014-12-08 |
| US20160338958A1 (en) | 2016-11-24 |
| US9717686B2 (en) | 2017-08-01 |
| EP3424564A1 (en) | 2019-01-09 |
| EP2773426A1 (en) | 2014-09-10 |
| JP2019123753A (ja) | 2019-07-25 |
| US20180015039A1 (en) | 2018-01-18 |
| US9370489B2 (en) | 2016-06-21 |
| JP2019023243A (ja) | 2019-02-14 |
| IL232344A0 (en) | 2014-06-30 |
| US20130115273A1 (en) | 2013-05-09 |
| JP6143767B2 (ja) | 2017-06-07 |
| US10213385B2 (en) | 2019-02-26 |
| EP2773426B1 (en) | 2018-08-22 |
| CN104023793A (zh) | 2014-09-03 |
| JP6549172B2 (ja) | 2019-07-24 |
| IL258740B (en) | 2019-01-14 |
| RU2014120216A (ru) | 2015-12-10 |
| BR112014010291A2 (pt) | 2017-04-18 |
| US20190175505A1 (en) | 2019-06-13 |
| IL232344B (en) | 2018-05-31 |
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