MX360245B - Composiciones que comprenden inmunoglobulinas de tipo secretor. - Google Patents

Composiciones que comprenden inmunoglobulinas de tipo secretor.

Info

Publication number
MX360245B
MX360245B MX2014010754A MX2014010754A MX360245B MX 360245 B MX360245 B MX 360245B MX 2014010754 A MX2014010754 A MX 2014010754A MX 2014010754 A MX2014010754 A MX 2014010754A MX 360245 B MX360245 B MX 360245B
Authority
MX
Mexico
Prior art keywords
secretory
compositions
immunoglobulins
methods
iga
Prior art date
Application number
MX2014010754A
Other languages
English (en)
Other versions
MX2014010754A (es
Inventor
Zuercher Adrian
Corthésy Blaise
Longet Stéphanie
Loetscher Marius
Miescher Sylvia
Original Assignee
Csl Behring Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP20120158931 external-priority patent/EP2636682A1/en
Application filed by Csl Behring Ag filed Critical Csl Behring Ag
Publication of MX2014010754A publication Critical patent/MX2014010754A/es
Publication of MX360245B publication Critical patent/MX360245B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención se refiere a un método para producir una composición que comprende IgA y/o IgM de tipo secretor in vitro, caracterizado porque comprende el paso: a) mezclar una composición de proteína derivada de la sangre que tiene menos de 80% de inmunoglobulina que porta la cadena J con el componente secretor; en donde dicha IgA y/o IgM de tipo secretor tiene características funcionales y bioquímicas similares a IgA y/o IgM secretoras derivadas de mucosa.
MX2014010754A 2012-03-09 2013-03-08 Composiciones que comprenden inmunoglobulinas de tipo secretor. MX360245B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20120158931 EP2636682A1 (en) 2012-03-09 2012-03-09 Compositions comprising secretory-like immunoglobulins
EP12168343 2012-05-16
PCT/EP2013/054697 WO2013132052A1 (en) 2012-03-09 2013-03-08 Compositions comprising secretory - like immunoglobulins

Publications (2)

Publication Number Publication Date
MX2014010754A MX2014010754A (es) 2014-12-05
MX360245B true MX360245B (es) 2018-10-26

Family

ID=47846003

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014010754A MX360245B (es) 2012-03-09 2013-03-08 Composiciones que comprenden inmunoglobulinas de tipo secretor.

Country Status (17)

Country Link
US (3) US10221233B2 (es)
EP (1) EP2822967B1 (es)
JP (3) JP2015510875A (es)
KR (1) KR102142261B1 (es)
CN (2) CN104254542A (es)
AU (1) AU2013201393B2 (es)
BR (1) BR112014022240A2 (es)
CA (1) CA2866634C (es)
DK (1) DK2822967T3 (es)
ES (1) ES2751976T3 (es)
IL (1) IL234449B (es)
MX (1) MX360245B (es)
NZ (1) NZ629072A (es)
PL (1) PL2822967T3 (es)
RU (1) RU2644240C2 (es)
SG (1) SG11201404958SA (es)
WO (1) WO2013132052A1 (es)

Families Citing this family (15)

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EP2636681A1 (en) 2012-03-09 2013-09-11 CSL Behring AG Process for enriching IgA
MX360245B (es) * 2012-03-09 2018-10-26 Csl Behring Ag Composiciones que comprenden inmunoglobulinas de tipo secretor.
US9458230B2 (en) 2013-01-04 2016-10-04 Wisconsin Alumni Research Foundation Secretory IGA compositions, methods of making and methods of use thereof
US9468674B2 (en) * 2013-09-24 2016-10-18 Wisconsin Alumni Research Foundation Methods of use of secretory IgA
RU2729546C2 (ru) 2014-04-03 2020-08-07 Цсл Беринг Аг Распыление иммуноглобулина
RU2599029C1 (ru) * 2015-07-16 2016-10-10 Игорь Геннадьевич Ковшик Химерный иммуноглобулиновый препарат, обладающий специфическим противовирусным или антибактериальным действием
PL3429622T3 (pl) 2016-03-14 2021-11-02 Biotest Ag Leczenie ciężkiego pozaszpitalnego zapalenia płuc
EP3558362A1 (en) 2016-12-20 2019-10-30 CSL Behring AG Methods for affecting salmonella infections
BR112020005742A2 (pt) 2017-09-21 2020-10-13 Umc Utrecht Holding B.V. anticorpo anti-gd2 para o tratamento de neuroblastoma
CN110724176B (zh) * 2018-07-16 2021-10-26 北京豪思生物科技有限公司 一种治疗阿尔茨海默症的血浆蛋白分离物及其制备方法和应用
EP3886902A1 (en) 2018-11-30 2021-10-06 CSL Behring AG Methods and compositions for preventing or treating acute exacerbations with polyclonal immunoglobulin
CN114096559B (zh) 2019-03-27 2026-03-20 蒂嘉特克斯公司 工程化iga抗体及其使用方法
US12612467B2 (en) * 2022-09-21 2026-04-28 Michael R. Simon Treatment of necrotizing enterocolitis with semisynthetic polyclonal human secretory immunoglobin A
WO2024151506A1 (en) * 2023-01-13 2024-07-18 Simon Michael R Process for preparation of secretory iga and secretory igm and use thereof for treating necrotizing enterocolitis

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EP2636684A1 (en) 2012-03-09 2013-09-11 CSL Behring AG Prevention of infection
EP2636681A1 (en) 2012-03-09 2013-09-11 CSL Behring AG Process for enriching IgA
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Also Published As

Publication number Publication date
JP2015510875A (ja) 2015-04-13
JP2021038246A (ja) 2021-03-11
US10385117B2 (en) 2019-08-20
KR20140132770A (ko) 2014-11-18
CN104254542A (zh) 2014-12-31
US20140371431A1 (en) 2014-12-18
KR102142261B1 (ko) 2020-08-11
US20190256577A1 (en) 2019-08-22
JP7575920B2 (ja) 2024-10-30
CA2866634C (en) 2022-07-19
RU2014140744A (ru) 2016-04-27
US11623948B2 (en) 2023-04-11
AU2013201393B2 (en) 2015-08-27
EP2822967A1 (en) 2015-01-14
AU2013201393A1 (en) 2013-09-26
CN111116735A (zh) 2020-05-08
NZ629072A (en) 2016-03-31
EP2822967B1 (en) 2019-08-07
WO2013132052A1 (en) 2013-09-12
HK1204628A1 (en) 2015-11-27
SG11201404958SA (en) 2014-11-27
PL2822967T3 (pl) 2020-01-31
IL234449B (en) 2018-07-31
MX2014010754A (es) 2014-12-05
US10221233B2 (en) 2019-03-05
US20150056180A1 (en) 2015-02-26
BR112014022240A2 (pt) 2017-08-01
JP2019038834A (ja) 2019-03-14
DK2822967T3 (da) 2019-10-07
RU2644240C2 (ru) 2018-02-08
US20170058018A2 (en) 2017-03-02
CA2866634A1 (en) 2013-09-12
ES2751976T3 (es) 2020-04-02

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