MX359376B - Metodo y kit para la determinacion de cobre libre en suero. - Google Patents

Metodo y kit para la determinacion de cobre libre en suero.

Info

Publication number
MX359376B
MX359376B MX2015005758A MX2015005758A MX359376B MX 359376 B MX359376 B MX 359376B MX 2015005758 A MX2015005758 A MX 2015005758A MX 2015005758 A MX2015005758 A MX 2015005758A MX 359376 B MX359376 B MX 359376B
Authority
MX
Mexico
Prior art keywords
free copper
determination
serum
kit
disease
Prior art date
Application number
MX2015005758A
Other languages
English (en)
Other versions
MX2015005758A (es
Inventor
Antonio Colabufo Nicola
Squitti Rosanna
Original Assignee
Canox4Drug S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canox4Drug S P A filed Critical Canox4Drug S P A
Publication of MX2015005758A publication Critical patent/MX2015005758A/es
Publication of MX359376B publication Critical patent/MX359376B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a un nuevo método para la determinación de cobre libre en suero. En particular, a un método con un alto grado de sensibilidad y precisión para la determinación de cobre libre en muestras de suero de pacientes con la enfermedad de Alzheimer, la enfermedad de Wilson y otras formas de dishomeostasis de cobre libre. La invención también se refiere a kits para la determinación de cobre libre en suero que comprenden dispositivos de filtro y sondas fluorescentes de cumarina.
MX2015005758A 2012-11-07 2012-11-07 Metodo y kit para la determinacion de cobre libre en suero. MX359376B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2012/072063 WO2014071973A1 (en) 2012-11-07 2012-11-07 Method and kit for determination of free copper in serum

Publications (2)

Publication Number Publication Date
MX2015005758A MX2015005758A (es) 2015-08-12
MX359376B true MX359376B (es) 2018-09-24

Family

ID=47137744

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015005758A MX359376B (es) 2012-11-07 2012-11-07 Metodo y kit para la determinacion de cobre libre en suero.

Country Status (11)

Country Link
US (1) US10663458B2 (es)
EP (1) EP2917739B1 (es)
JP (1) JP2015535345A (es)
CN (1) CN104823056A (es)
AU (1) AU2012394195A1 (es)
BR (1) BR112015010399A2 (es)
CA (1) CA2890830A1 (es)
ES (1) ES2669986T3 (es)
HK (1) HK1209832A1 (es)
MX (1) MX359376B (es)
WO (1) WO2014071973A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20130253A1 (it) * 2013-04-29 2014-10-30 Canox4Drug S P A Metodo per la determinazione del rame libero
CN104177321B (zh) * 2014-08-06 2015-10-21 济南大学 一种基于苯并吡喃二酮的铜离子荧光探针及其制备方法
CN105738337A (zh) * 2016-02-29 2016-07-06 南京林业大学 异鼠李素在测定铜离子中的应用
CN105784665B (zh) * 2016-05-19 2019-09-06 南京林业大学 异鼠李素与环糊精的复配液及其应用
WO2018008764A1 (ja) * 2016-07-08 2018-01-11 味の素株式会社 軽度認知障害又はアルツハイマー型認知症の評価方法
CN109111434B (zh) * 2018-10-29 2020-07-07 浙江外国语学院 一种香豆素类镍离子荧光探针及其制备方法、晶体制备方法及应用
IT201900009060A1 (it) 2019-06-14 2020-12-14 Igea Pharma Nv Dispositivo e metodo per il dosaggio rapido dello ione rame e di altri metalli pesanti su microvolumi di sangue umano capillare e di altri fluidi biologici

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879098A (en) * 1985-01-25 1989-11-07 Becton, Dickinson And Company Device for the separation of the lighter fraction from the heavier fraction of a liquid sample
DE4208645A1 (de) * 1992-03-18 1993-09-23 Bayer Ag Optischer festphasenbiosensor auf basis fluoreszenzfarbstoffmarkierter polyionischer schichten
US7553869B2 (en) * 2006-07-28 2009-06-30 Pierce Biotechnology, Inc. Protein probe compounds, compositions, and methods
US20080268491A1 (en) 2007-02-18 2008-10-30 Pipex, Inc. Instruments for direct detection of free metals in fluids and methods to diagnose metal-related diseases and determine pharmacologic dosing regimens
US8058057B2 (en) * 2008-05-30 2011-11-15 Corning Incorporated Cell culture apparatus and method
US20100129290A1 (en) 2008-11-26 2010-05-27 I.S.T. Corporation Smart contrast agent and detection method for detecting transition metal ions
US20100227794A1 (en) 2008-11-26 2010-09-09 I.S.T. Corporation Smart contrast agent and method for detecting transition metal ions and treating related disorders
US20120058564A1 (en) * 2008-12-01 2012-03-08 Karmakar Nivedita Gohil Test kit and method for measurement of metals in biological fluids
KR101129574B1 (ko) 2009-12-15 2012-03-27 고려대학교 산학협력단 구리 이온 선택성을 갖는 쿠마린 유도체 및 이를 이용한 발광센서

Also Published As

Publication number Publication date
EP2917739B1 (en) 2018-02-21
US20150276722A1 (en) 2015-10-01
WO2014071973A1 (en) 2014-05-15
US10663458B2 (en) 2020-05-26
CA2890830A1 (en) 2014-05-15
ES2669986T3 (es) 2018-05-29
EP2917739A1 (en) 2015-09-16
BR112015010399A2 (pt) 2017-07-11
AU2012394195A1 (en) 2015-05-28
CN104823056A (zh) 2015-08-05
JP2015535345A (ja) 2015-12-10
HK1209832A1 (en) 2016-04-08
MX2015005758A (es) 2015-08-12

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