MX355504B - Éster de cera de proteína portadora de acil-acil sintasas. - Google Patents
Éster de cera de proteína portadora de acil-acil sintasas.Info
- Publication number
- MX355504B MX355504B MX2014003670A MX2014003670A MX355504B MX 355504 B MX355504 B MX 355504B MX 2014003670 A MX2014003670 A MX 2014003670A MX 2014003670 A MX2014003670 A MX 2014003670A MX 355504 B MX355504 B MX 355504B
- Authority
- MX
- Mexico
- Prior art keywords
- acyl
- wax ester
- acp
- alcohol
- acp wax
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/0108—Long-chain acyl-[acyl-carrier-protein] reductase (1.2.1.80)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/0102—Diacylglycerol O-acyltransferase (2.3.1.20)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01075—Long-chain-alcohol O-fatty-acyltransferase (2.3.1.75)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01084—Alcohol O-acetyltransferase (2.3.1.84)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/02—Thioester hydrolases (3.1.2)
- C12Y301/0202—Acyl-CoA hydrolase (3.1.2.20)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/99—Other Carbon-Carbon Lyases (1.4.99)
- C12Y401/99005—Octadecanal decarbonylase (4.1.99.5)
Abstract
La presente invención se refiere a métodos independientes de acil-CoA para la producción de un éster de cera en células hospederas recombinantes diseñadas para expresar una éster de cera acil-ACP sintasa, y una acil-ACP reductasa formadora de alcoholes; los métodos de la invención puede tener lugar en microorganismos fotosintéticos, y en particular en cianobacterias; también se proporcionan las moléculas aisladas de nucleótidos y los vectores que expresan la éster de cera acil-ACP sintasa y/o una acil-ACP reductasa formadora de alcoholes, las células hospederas recombinantes que expresan una éster de cera acil-ACP sintasa y opcionalmente, una acil-ACP reductasa formadora de alcoholes, y los sistemas para la producción de un éster de cera a través de una vía independiente de acil-CoA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161539640P | 2011-09-27 | 2011-09-27 | |
PCT/US2012/027899 WO2013048557A1 (en) | 2011-09-27 | 2012-03-06 | Acyl-acp wax ester synthases |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014003670A MX2014003670A (es) | 2014-04-30 |
MX355504B true MX355504B (es) | 2018-04-19 |
Family
ID=47911679
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014003670A MX355504B (es) | 2011-09-27 | 2012-03-06 | Éster de cera de proteína portadora de acil-acil sintasas. |
Country Status (10)
Country | Link |
---|---|
US (2) | US8921090B2 (es) |
EP (2) | EP2753701B1 (es) |
CN (1) | CN103975070A (es) |
AU (1) | AU2012316749B2 (es) |
BR (1) | BR112014007115A2 (es) |
ES (1) | ES2678647T3 (es) |
IL (1) | IL231584A0 (es) |
MX (1) | MX355504B (es) |
PT (1) | PT2753701T (es) |
WO (2) | WO2013048557A1 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9133406B2 (en) * | 2009-09-25 | 2015-09-15 | REG Life Sciences, LLC | Production of fatty acid derivatives |
AU2011349729B2 (en) * | 2010-12-23 | 2015-09-24 | Exxonmobil Research And Engineering Company | Genetically engineered microorganisms comprising 4-hydroxybenzoly-CoA thioesterases and methods of using the same for producing free fatty acids and fatty acid derivatives |
WO2012135668A1 (en) | 2011-03-31 | 2012-10-04 | Exxonmobil Research And Engineering Company | Metabolic pathway targeting by transcription factor overexpression |
US8962299B2 (en) | 2012-02-29 | 2015-02-24 | Exxonmobil Research And Engineering Company | Four-gene pathway for wax ester synthesis |
US9650655B2 (en) | 2012-07-20 | 2017-05-16 | Codexis, Inc. | Production of fatty alcohols from engineered microorganisms |
KR20150040359A (ko) | 2012-08-10 | 2015-04-14 | 오피엑스 바이오테크놀로지스, 인크. | 지방산 및 지방산 유도된 산물의 생산을 위한 미생물 및 방법 |
MX366179B (es) | 2012-09-14 | 2019-07-01 | Reg Life Sciences Llc | Variantes de enzima con propiedades de ester sintasa mejoradas. |
US20150057465A1 (en) | 2013-03-15 | 2015-02-26 | Opx Biotechnologies, Inc. | Control of growth-induction-production phases |
EP2971021A4 (en) | 2013-03-15 | 2016-12-21 | Genomatica Inc | MICROORGANISMS AND METHODS FOR PRODUCING BUTADIENE AND RELATED COMPOUNDS BY ASSIMILATING FORMAT |
US11814664B2 (en) | 2013-05-24 | 2023-11-14 | Genomatica, Inc. | Microorganisms and methods for producing (3R)-hydroxybutyl (3R)-hydroxybutyrate |
CN106795483A (zh) | 2013-07-19 | 2017-05-31 | 嘉吉公司 | 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法 |
US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
WO2015077752A1 (en) | 2013-11-25 | 2015-05-28 | Genomatica, Inc. | Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol |
US10513713B2 (en) | 2014-04-30 | 2019-12-24 | The Regents Of The University Of California | Modified host cells having tolerance to α-olefins |
EP2993228B1 (en) * | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
EP3191581B9 (en) * | 2014-09-09 | 2023-10-11 | Lumen Bioscience, Inc. | Targeted mutagenesis in spirulina |
EP3173478A1 (en) * | 2015-11-25 | 2017-05-31 | Evonik Degussa GmbH | Biotechnological production of omega-functionalised carboxylic acids and esters thereof |
ES2841298T3 (es) * | 2016-03-04 | 2021-07-08 | Total Raffinage Chimie | Procedimiento de producción de ácidos grasos |
JP2020506702A (ja) | 2017-02-02 | 2020-03-05 | カーギル インコーポレイテッド | C6−c10脂肪酸誘導体を生成する遺伝子組み換え細胞 |
CN112299562A (zh) * | 2019-07-29 | 2021-02-02 | 仲恺农业工程学院 | 利用酵母分泌物促进微藻降解碳、氮、磷的方法 |
AU2021379745A1 (en) * | 2020-11-13 | 2023-07-06 | Berkeley Fermentation Science Inc. | Genetically engineered yeast cells and methods of use thereof |
CN117229963B (zh) * | 2023-09-21 | 2024-03-22 | 东北林业大学 | 一株防治核桃焦叶症的韩国假单胞菌ybz2及其应用 |
Family Cites Families (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5254466A (en) | 1989-11-06 | 1993-10-19 | Henkel Research Corporation | Site-specific modification of the candida tropicals genome |
US5298421A (en) | 1990-04-26 | 1994-03-29 | Calgene, Inc. | Plant medium-chain-preferring acyl-ACP thioesterases and related methods |
US5411879A (en) | 1991-02-22 | 1995-05-02 | Calgene Inc. | Fatty acyl reductases |
US5403918A (en) | 1991-02-22 | 1995-04-04 | Calgene, Inc. | Fatty acyl reductase |
US5723747A (en) | 1991-02-22 | 1998-03-03 | Calgene, Inc. | Wax esters in transformed plants |
CA2079113A1 (en) | 1991-02-22 | 1992-08-23 | Calgene, Inc. | Seed plant fatty acyl reductase proteins and genes |
US5455167A (en) | 1991-05-21 | 1995-10-03 | Calgene Inc. | Medium-chain thioesterases in plants |
US5654495A (en) | 1992-10-30 | 1997-08-05 | Calgene, Inc. | Production of myristate in plant cells |
US6492509B1 (en) | 1994-06-23 | 2002-12-10 | Calgene Llc | Fatty acyl-CoA: fatty alcohol acyltransferases |
US5851796A (en) | 1995-06-07 | 1998-12-22 | Yale University | Autoregulatory tetracycline-regulated system for inducible gene expression in eucaryotes |
US6143538A (en) | 1997-02-20 | 2000-11-07 | The United States Of America As Represented By The United States Department Of Energy | Fatty acyl-CoA reductase |
WO2002099111A2 (en) | 2001-06-07 | 2002-12-12 | National Research Council Of Canada | Anther-specific taa1 genes encoding fatty acyl co-a reductases, and uses thereof |
ATE448315T1 (de) | 2002-03-01 | 2009-11-15 | Monsanto Technology Llc | Wachsestersynthase-dna-sequenz, protein und verwendungen davon |
US7135290B2 (en) | 2003-04-12 | 2006-11-14 | Solazyme, Inc. | Methods and compositions for evolving hydrogenase genes |
EP1752532A1 (en) | 2005-08-09 | 2007-02-14 | Helmholtz-Zentrum für Infektionsforschung GmbH | Extracellular polyhydroxyalkanoates produced by genetically engineered microorganisms |
WO2008100251A1 (en) | 2007-02-13 | 2008-08-21 | Ls9, Inc. | Modified microorganism uses therefor |
US8110670B2 (en) | 2006-05-19 | 2012-02-07 | Ls9, Inc. | Enhanced production of fatty acid derivatives |
MX344588B (es) | 2006-05-19 | 2016-12-20 | Reg Life Sciences Llc | Produccion de acidos grasos y derivados de los mismos. |
MX2009004221A (es) | 2006-10-20 | 2009-09-10 | Univ Arizona State | Cianobacterias modificadas. |
KR20100015763A (ko) | 2007-03-28 | 2010-02-12 | 엘에스9, 인코포레이티드 | 지방산 유도체의 생산 증가 |
WO2008151149A2 (en) | 2007-06-01 | 2008-12-11 | Solazyme, Inc. | Production of oil in microorganisms |
WO2009006430A1 (en) | 2007-06-29 | 2009-01-08 | The Regents Of The University Of California | Host cells and methods for producing fatty acid derived compounds |
WO2009009391A2 (en) | 2007-07-06 | 2009-01-15 | Ls9, Inc. | Systems and methods for the production of fatty esters |
US7897369B2 (en) * | 2007-08-27 | 2011-03-01 | Regents Of The University Of Minnesota | Isoprenoid wax ester synthases, isoprenoid acyl CoA-synthetases, and uses thereof |
MX2010006539A (es) | 2007-12-11 | 2011-02-23 | Synthetic Genomics Inc | Secrecion de acidos grasos por parte de microorganismos fotosinteticos. |
US8048654B2 (en) | 2010-06-09 | 2011-11-01 | Joule Unlimited Technologies, Inc. | Methods and compositions for the recombinant biosynthesis of fatty acids and esters |
EP2706111A1 (en) | 2008-03-03 | 2014-03-12 | Joule Unlimited Technologies, Inc. | Engineered CO2 fixing microorganisms producing carbon-based products of interest |
WO2009124070A1 (en) | 2008-03-31 | 2009-10-08 | Kuehnle Agrosystems, Inc. | Nuclear based expression of genes for production of biofuels and process co-products in algae |
WO2009140701A2 (en) | 2008-05-16 | 2009-11-19 | Synthetic Genomics, Inc. | Delivery into cells using ultra-short pulse lasers |
WO2009140696A2 (en) | 2008-05-16 | 2009-11-19 | Ls9, Inc. | Methods and compositions for producing hydrocarbons |
US20120094338A1 (en) | 2008-07-22 | 2012-04-19 | Li zhong kui | Continuous production and excretion of waxy products from photosynthetic organisms |
WO2010033921A2 (en) | 2008-09-19 | 2010-03-25 | President And Fellows Of Harvard College | Photoautotrophic adipogenesis technology (phat) |
US8097439B2 (en) | 2008-10-07 | 2012-01-17 | Ls9, Inc. | Methods and compositions for producing fatty aldehydes |
AU2009308236B2 (en) | 2008-10-23 | 2016-06-30 | Lumen Bioscience, Inc. | Modified photosynthetic microorganisms for producing triglycerides |
CA3041892C (en) | 2008-10-28 | 2022-03-15 | REG Life Sciences, LLC | Methods for producing a fatty alcohol in a host cell |
MX2011005630A (es) | 2008-11-28 | 2011-09-28 | Solazyme Inc | Producción de aceites específicos en microorganismos heterótroficos recombinantes. |
AU2009329970B2 (en) | 2008-12-23 | 2016-07-28 | Genomatica, Inc. | Methods and compositions related to thioesterase enzymes |
WO2010078584A1 (en) * | 2009-01-05 | 2010-07-08 | Arizona Board Of Regents | Cyanobacterium that produces neutral lipids |
US20100203614A1 (en) | 2009-02-12 | 2010-08-12 | Utah State University | Fatty aldehyde reductase |
WO2010118410A1 (en) | 2009-04-10 | 2010-10-14 | Ls9, Inc. | Production of fatty acid derivatives |
WO2010126891A1 (en) | 2009-04-27 | 2010-11-04 | Ls9, Inc. | Production of fatty acid esters |
BRPI1010920B1 (pt) | 2009-05-22 | 2020-04-28 | Codexis Inc | processo para a produção biológica de álcoois graxos |
US8956834B2 (en) | 2009-06-29 | 2015-02-17 | Synthetic Genomics, Inc. | Acyl-ACP thioesterase genes and uses therefor |
CA2766585C (en) | 2009-06-30 | 2016-03-01 | Codexis, Inc. | Production of fatty alcohols with fatty alcohol forming acyl-coa reductases (far) |
US7794969B1 (en) | 2009-07-09 | 2010-09-14 | Joule Unlimited, Inc. | Methods and compositions for the recombinant biosynthesis of n-alkanes |
EP2464722B1 (en) | 2009-08-11 | 2017-10-04 | Synthetic Genomics, Inc. | Microbial production of fatty alcohols |
US9133406B2 (en) * | 2009-09-25 | 2015-09-15 | REG Life Sciences, LLC | Production of fatty acid derivatives |
EP2503887B1 (en) | 2009-11-24 | 2016-01-06 | Merck Sharp & Dohme Corp. | Substituted biaryl derivatives and methods of use thereof |
CN102741273A (zh) * | 2009-12-16 | 2012-10-17 | 华盛顿大学 | 毒素-免疫系统 |
US8980613B2 (en) | 2010-04-06 | 2015-03-17 | Matrix Genetics, Llc | Modified photosynthetic microorganisms for producing lipids |
BR112012032279A2 (pt) | 2010-06-18 | 2018-08-28 | Univ Denmark Tech Dtu | produção de biodiesel por meio de levedura a partir de lignocelulose e glicerol |
WO2012087963A1 (en) | 2010-12-20 | 2012-06-28 | Targeted Growth, Inc. | Modified photosynthetic microorganisms for producing lipids |
US9175256B2 (en) | 2010-12-23 | 2015-11-03 | Exxonmobil Research And Engineering Company | Production of fatty acids and fatty acid derivatives by recombinant microorganisms expressing polypeptides having lipolytic activity |
AU2011349729B2 (en) | 2010-12-23 | 2015-09-24 | Exxonmobil Research And Engineering Company | Genetically engineered microorganisms comprising 4-hydroxybenzoly-CoA thioesterases and methods of using the same for producing free fatty acids and fatty acid derivatives |
EP2906587B9 (en) * | 2011-04-01 | 2021-01-06 | Genomatica, Inc. | Methods and compositions for improved production of fatty acids and derivatives thereof |
US8962299B2 (en) | 2012-02-29 | 2015-02-24 | Exxonmobil Research And Engineering Company | Four-gene pathway for wax ester synthesis |
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2012
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- 2012-03-06 US US13/413,426 patent/US8921090B2/en active Active
- 2012-03-06 MX MX2014003670A patent/MX355504B/es active IP Right Grant
- 2012-03-06 ES ES12835320.8T patent/ES2678647T3/es active Active
- 2012-03-06 PT PT128353208T patent/PT2753701T/pt unknown
- 2012-03-06 EP EP12835320.8A patent/EP2753701B1/en not_active Not-in-force
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US8921090B2 (en) | 2014-12-30 |
AU2012316749B2 (en) | 2017-06-29 |
WO2013049423A1 (en) | 2013-04-04 |
BR112014007115A2 (pt) | 2017-04-25 |
EP2761012A1 (en) | 2014-08-06 |
EP2761012B1 (en) | 2017-08-09 |
PT2753701T (pt) | 2018-08-10 |
WO2013048557A1 (en) | 2013-04-04 |
US20130078686A1 (en) | 2013-03-28 |
EP2761012A4 (en) | 2015-04-15 |
US20130078684A1 (en) | 2013-03-28 |
ES2678647T3 (es) | 2018-08-14 |
AU2012316749A1 (en) | 2014-04-10 |
AU2012316749A2 (en) | 2014-09-04 |
EP2753701A1 (en) | 2014-07-16 |
CN103975070A (zh) | 2014-08-06 |
EP2753701A4 (en) | 2015-04-08 |
US9017975B2 (en) | 2015-04-28 |
MX2014003670A (es) | 2014-04-30 |
IL231584A0 (en) | 2014-05-28 |
EP2753701B1 (en) | 2018-05-02 |
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