MX355362B - Variantes de proteasa. - Google Patents
Variantes de proteasa.Info
- Publication number
- MX355362B MX355362B MX2015008451A MX2015008451A MX355362B MX 355362 B MX355362 B MX 355362B MX 2015008451 A MX2015008451 A MX 2015008451A MX 2015008451 A MX2015008451 A MX 2015008451A MX 355362 B MX355362 B MX 355362B
- Authority
- MX
- Mexico
- Prior art keywords
- protease variants
- proteases
- relates
- protease
- threrof
- Prior art date
Links
- 108091005804 Peptidases Proteins 0.000 title abstract 5
- 239000004365 Protease Substances 0.000 title abstract 5
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 title abstract 3
- 102000035195 Peptidases Human genes 0.000 abstract 2
- 241000228182 Thermoascus aurantiacus Species 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
- C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
La presente invención se refiere a proteasas que tienen por lo menos 75% de identidad con una proteasa derivada de Thermoascus aurantiacus y que comprende por lo menos una modificación en la secuencia de aminoácidos de la misma. Estas variantes de proteasa tienen termoestabilidad mejorada. La invención también se relaciona con ADN que codifica para estas proteasas, métodos de su producción así como uso de los mismos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28560109P | 2009-12-11 | 2009-12-11 | |
| PCT/US2010/059814 WO2011072191A2 (en) | 2009-12-11 | 2010-12-10 | Protease variants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX355362B true MX355362B (es) | 2018-04-17 |
Family
ID=44146191
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012006548A MX2012006548A (es) | 2009-12-11 | 2010-12-10 | Variantes de proteasa. |
| MX2015008451A MX355362B (es) | 2009-12-11 | 2010-12-10 | Variantes de proteasa. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012006548A MX2012006548A (es) | 2009-12-11 | 2010-12-10 | Variantes de proteasa. |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9040280B2 (es) |
| EP (1) | EP2510093B1 (es) |
| CN (2) | CN104774823B (es) |
| AU (1) | AU2010328033B2 (es) |
| CA (1) | CA2783820C (es) |
| DK (1) | DK2510093T3 (es) |
| ES (1) | ES2668202T3 (es) |
| MX (2) | MX2012006548A (es) |
| WO (1) | WO2011072191A2 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103608460B (zh) | 2010-12-22 | 2017-08-29 | 诺维信北美公司 | 用于产生发酵产物的工艺 |
| CN103930543B (zh) | 2011-09-06 | 2020-11-27 | 诺维信公司 | 葡糖淀粉酶变体和编码它们的多核苷酸 |
| US9353362B2 (en) | 2011-10-11 | 2016-05-31 | Novozymes A/S | Glucoamylase variants and polynucleotides encoding same |
| EP2766490B1 (en) | 2011-10-11 | 2017-04-12 | Novozymes North America, Inc. | Liquefaction process for producing fermentation products |
| IN2014CN04905A (es) * | 2011-12-02 | 2015-09-18 | Novozymes As | |
| US9175316B2 (en) * | 2012-12-12 | 2015-11-03 | Ebio, Llc | Efficient production of biofuels from cells carrying a metabolic-bypass gene cassette |
| CA2869047C (en) | 2012-03-30 | 2022-11-01 | Novozymes North America, Inc. | Processes of producing fermentation products |
| ES2935920T3 (es) | 2012-03-30 | 2023-03-13 | Novozymes North America Inc | Procesos de elaboración de productos de fermentación |
| CN105339501A (zh) | 2013-06-24 | 2016-02-17 | 诺维信公司 | 用于从发酵产物过程中回收油的方法以及用于生产发酵产物的方法 |
| US11939552B2 (en) | 2013-06-24 | 2024-03-26 | Novozymes A/S | Process of recovering oil |
| DK3022300T3 (en) | 2013-07-17 | 2018-10-22 | Novozymes As | : Pullulan chimeras and polynucleotides encoding them |
| US9951364B2 (en) * | 2013-09-11 | 2018-04-24 | Novozymes A/S | Processes for producing fermentation products |
| EP3097192B1 (en) | 2014-01-22 | 2018-07-25 | Novozymes A/S | Pullulanase variants and polynucleotides encoding same |
| WO2016062875A2 (en) | 2014-10-23 | 2016-04-28 | Novozymes A/S | Glucoamylase variants and polynucleotides encoding same |
| CN109661465A (zh) | 2016-07-21 | 2019-04-19 | 诺维信公司 | 丝氨酸蛋白酶变体以及对其进行编码的多核苷酸 |
| FI3487996T3 (fi) | 2016-07-21 | 2024-07-10 | Novozymes As | Seriiniproteaasivariantteja ja niitä koodittavia polynukleotideja |
| US10889836B2 (en) | 2016-11-23 | 2021-01-12 | Novozymes A/S | Yeast for ethanol production |
| WO2018188667A1 (en) * | 2017-04-14 | 2018-10-18 | Novozymes A/S | Processes for solubilizing municipal solid waste with enzyme compositions comprising protease and enzyme compositions thereof |
| CN107384900B (zh) * | 2017-08-01 | 2019-08-27 | 中国农业科学院饲料研究所 | 一种真菌来源的酸性蛋白酶6749及其基因和应用 |
| MX2020008309A (es) | 2018-02-15 | 2020-10-14 | Novozymes As | Levadura mejorada para produccion de etanol. |
| WO2020206058A1 (en) | 2019-04-02 | 2020-10-08 | Novozymes A/S | Process for producing a fermentation product |
| JP2022528694A (ja) * | 2019-04-08 | 2022-06-15 | ノボザイムス アクティーゼルスカブ | ゼラチンを抽出するための方法 |
| CN112048518B (zh) * | 2020-08-22 | 2022-06-24 | 江西农业大学 | 一种玉米醇溶蛋白降解酶的制备方法及其应用 |
| CN114574468A (zh) * | 2022-02-17 | 2022-06-03 | 皖西学院 | 一种高活性高热稳定性的蛋白酶突变体及其制备、应用 |
| CN115851672B (zh) * | 2022-11-30 | 2024-12-31 | 山东龙昌动物保健品股份有限公司 | 一种木聚糖酶突变体及胆汁酸复配酶制剂和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| PT97110B (pt) | 1990-03-23 | 1998-11-30 | Gist Brocades Nv | Processo para catalisar reaccoes acelaraveis por enzimas, mediante adicao ao meio reaccional de sementes de plantas transgenicas e para obtencao das referidas sementes |
| US5231017A (en) | 1991-05-17 | 1993-07-27 | Solvay Enzymes, Inc. | Process for producing ethanol |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| US5689054A (en) | 1994-03-17 | 1997-11-18 | The United States Of America As Represented By The Secretary Of Agriculture | Low phytic acid mutants and selection thereof |
| DE4422198C2 (de) | 1994-06-24 | 1997-08-28 | Audi Ag | Verfahren zum Steuern der elektrischen Beheizung eines Katalysators |
| ATE294871T1 (de) | 1994-06-30 | 2005-05-15 | Novozymes Biotech Inc | Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren |
| NZ330940A (en) | 1997-07-24 | 2000-02-28 | F | Production of consensus phytases from fungal origin using computer programmes |
| ATE302845T1 (de) | 2000-06-02 | 2005-09-15 | Novozymes As | Cutinase-varianten |
| EP1456369B1 (en) * | 2001-12-07 | 2009-11-18 | Novozymes A/S | Polypeptides having protease activity and nucleic acids encoding same |
| ES2356703T3 (es) * | 2004-12-22 | 2011-04-12 | Novozymes A/S | Enzimas híbridas que consisten en una primera secuencia de aminoácidos de endoamilasa y un módulo de unión de carbohidratos como segunda secuencia de aminoácidos. |
| WO2007044993A2 (en) * | 2005-10-12 | 2007-04-19 | Genencor International, Inc. | Use and production of storage-stable neutral metalloprotease |
-
2010
- 2010-12-10 ES ES10803307.7T patent/ES2668202T3/es active Active
- 2010-12-10 EP EP10803307.7A patent/EP2510093B1/en active Active
- 2010-12-10 CN CN201510178227.XA patent/CN104774823B/zh active Active
- 2010-12-10 US US13/510,076 patent/US9040280B2/en active Active
- 2010-12-10 CN CN201080063729.3A patent/CN102753680B/zh active Active
- 2010-12-10 DK DK10803307.7T patent/DK2510093T3/en active
- 2010-12-10 AU AU2010328033A patent/AU2010328033B2/en active Active
- 2010-12-10 WO PCT/US2010/059814 patent/WO2011072191A2/en not_active Ceased
- 2010-12-10 MX MX2012006548A patent/MX2012006548A/es active IP Right Grant
- 2010-12-10 MX MX2015008451A patent/MX355362B/es unknown
- 2010-12-10 CA CA2783820A patent/CA2783820C/en active Active
-
2015
- 2015-04-20 US US14/690,937 patent/US10138473B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20120309067A1 (en) | 2012-12-06 |
| ES2668202T3 (es) | 2018-05-17 |
| AU2010328033A1 (en) | 2012-06-07 |
| CA2783820A1 (en) | 2011-06-16 |
| WO2011072191A3 (en) | 2012-04-19 |
| CN102753680B (zh) | 2015-05-13 |
| US10138473B2 (en) | 2018-11-27 |
| CN104774823B (zh) | 2020-04-10 |
| MX2012006548A (es) | 2012-07-10 |
| EP2510093A2 (en) | 2012-10-17 |
| AU2010328033B2 (en) | 2014-12-04 |
| WO2011072191A2 (en) | 2011-06-16 |
| CN102753680A (zh) | 2012-10-24 |
| DK2510093T3 (en) | 2018-06-06 |
| CA2783820C (en) | 2018-10-23 |
| US9040280B2 (en) | 2015-05-26 |
| US20150218545A1 (en) | 2015-08-06 |
| EP2510093B1 (en) | 2018-02-21 |
| CN104774823A (zh) | 2015-07-15 |
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