MX348229B - Derivados de 1,2,4-triazina para el tratamiento de infecciones virales. - Google Patents
Derivados de 1,2,4-triazina para el tratamiento de infecciones virales.Info
- Publication number
- MX348229B MX348229B MX2015004160A MX2015004160A MX348229B MX 348229 B MX348229 B MX 348229B MX 2015004160 A MX2015004160 A MX 2015004160A MX 2015004160 A MX2015004160 A MX 2015004160A MX 348229 B MX348229 B MX 348229B
- Authority
- MX
- Mexico
- Prior art keywords
- viral infections
- treatment
- triazine derivatives
- triazine
- derivatives
- Prior art date
Links
- 150000003920 1,2,4-triazines Chemical class 0.000 title abstract 2
- 208000036142 Viral infection Diseases 0.000 title abstract 2
- 230000009385 viral infection Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12306196.2A EP2712866A1 (en) | 2012-10-01 | 2012-10-01 | 1,2,4-triazine derivatives for the treatment of viral infections |
| PCT/EP2013/070488 WO2014053516A1 (en) | 2012-10-01 | 2013-10-01 | 1,2,4-triazine derivatives for the treatment of viral infections. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015004160A MX2015004160A (es) | 2016-02-05 |
| MX348229B true MX348229B (es) | 2017-05-31 |
Family
ID=46982496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015004160A MX348229B (es) | 2012-10-01 | 2013-10-01 | Derivados de 1,2,4-triazina para el tratamiento de infecciones virales. |
Country Status (21)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR201815062T4 (tr) | 2011-04-08 | 2018-11-21 | Janssen Sciences Ireland Uc | Viral enfeksiyonların tedavisine yönelik pirimidin deriveleri. |
| KR102025276B1 (ko) | 2011-11-09 | 2019-09-25 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 바이러스 감염 치료를 위한 퓨린 유도체 |
| PL2872515T3 (pl) | 2012-07-13 | 2017-05-31 | Janssen Sciences Ireland Uc | Puryny makrocykliczne do leczenia infekcji wirusowych |
| MX386924B (es) | 2012-10-10 | 2025-03-19 | Janssen Sciences Ireland Uc | Derivados pirrolo[3,2-d]pirimidínicos para el tratamiento de infecciones víricas y otras enfermedades. |
| EA035431B1 (ru) | 2012-11-16 | 2020-06-15 | Янссен Сайенсиз Айрлэнд Юси | Гетероциклические замещенные производные 2-амино-хиназолина в качестве модуляторов tlr7 и/или tlr8 для лечения вирусных инфекций |
| SG11201506639XA (en) | 2013-02-21 | 2015-09-29 | Janssen Sciences Ireland Uc | 2-aminopyrimidine derivatives for the treatment of viral infections |
| AU2014242954B2 (en) | 2013-03-29 | 2018-03-15 | Janssen Sciences Ireland Uc | Macrocyclic deaza-purinones for the treatment of viral infections |
| KR102280559B1 (ko) | 2013-05-24 | 2021-07-22 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 바이러스 감염 및 추가적인 질환의 치료를 위한 피리돈 유도체 |
| HRP20171720T1 (hr) | 2013-06-27 | 2017-12-29 | Janssen Sciences Ireland Uc | Derivati pirolo [3,2-d] pirimidina za liječenje virusnih infekcija i drugih bolesti |
| CN105492446B (zh) | 2013-07-30 | 2018-08-03 | 爱尔兰詹森科学公司 | 用于治疗病毒性感染的噻吩并[3,2-d]嘧啶衍生物 |
| CN109476675B (zh) | 2016-07-01 | 2022-12-09 | 爱尔兰詹森科学公司 | 用于治疗病毒性感染的二氢吡喃并嘧啶衍生物 |
| EP3519406B1 (en) * | 2016-09-29 | 2022-02-23 | Janssen Sciences Ireland Unlimited Company | Pyrimidine prodrugs for the treatment of viral infections and further diseases |
| TW201945003A (zh) | 2018-03-01 | 2019-12-01 | 愛爾蘭商健生科學愛爾蘭無限公司 | ２，４－二胺基喹唑啉衍生物及其醫學用途 |
| WO2020162705A1 (ko) | 2019-02-08 | 2020-08-13 | 성균관대학교산학협력단 | 톨-유사 수용체 7 또는 8 작용자와 콜레스테롤의 결합체 및 그 용도 |
| US20230100429A1 (en) | 2020-03-02 | 2023-03-30 | Progeneer Inc. | Live-pathogen-mimetic nanoparticles based on pathogen cell wall skeleton, and production method thereof |
| CN116056725A (zh) | 2020-08-04 | 2023-05-02 | 蛋白科技先鋒 | 活性位点暂时灭活的功能性药物与Toll样受体7或8激动剂的缀合物及其用途 |
| JP7690222B2 (ja) | 2020-08-04 | 2025-06-10 | プロジェニア インコーポレイテッド | 動力学的制御が可能なアジュバントを含むｍＲＮＡワクチン |
| EP4194008A4 (en) | 2020-08-04 | 2025-01-08 | Progeneer Inc. | Kinetically acting adjuvant ensemble |
| WO2024151953A1 (en) * | 2023-01-15 | 2024-07-18 | Viradem Inc. | Compounds and methods for treating diseases caused by sars-cov-2 and other coronaviruses |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2485531A1 (fr) * | 1980-06-25 | 1981-12-31 | Fabre Sa Pierre | Nouveaux n-oxydes de diaryl-5,6 as triazines 1-2-4, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
| DE69731823T2 (de) | 1996-07-03 | 2005-12-15 | Sumitomo Pharmaceuticals Co., Ltd. | Neue purinderivate |
| AU732361B2 (en) | 1997-11-28 | 2001-04-26 | Dainippon Sumitomo Pharma Co., Ltd. | Novel heterocyclic compounds |
| ES2442857T3 (es) * | 2004-08-10 | 2014-02-13 | Janssen Pharmaceutica Nv | Derivados de 1,2,4-triazin-6-ona inhibidores de VIH |
| CN101203519A (zh) | 2005-05-04 | 2008-06-18 | 辉瑞有限公司 | 用于治疗癌症和病毒感染如丙型肝炎的用作Toll样受体调节剂的2－酰氨基－6－氨基－8－氧代嘌呤衍生物 |
| ES2612890T3 (es) * | 2005-09-01 | 2017-05-19 | F. Hoffmann-La Roche Ag | Diaminopirimidinas como moduladores de P2X3 y P2X2/3 |
| RU2352565C1 (ru) * | 2007-10-08 | 2009-04-20 | Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" | 3-амино-6-ароилметил-5-гидрокси-1,2,4-триазины и способ их получения |
| PE20091236A1 (es) * | 2007-11-22 | 2009-09-16 | Astrazeneca Ab | Derivados de pirimidina como immunomoduladores de tlr7 |
| WO2012067269A1 (en) * | 2010-11-19 | 2012-05-24 | Dainippon Sumitomo Pharma Co., Ltd. | Aminoalkoxyphenyl compounds and their use in the treatment of disease |
-
2012
- 2012-10-01 EP EP12306196.2A patent/EP2712866A1/en not_active Withdrawn
-
2013
- 2013-10-01 EP EP13773690.6A patent/EP2903976B1/en active Active
- 2013-10-01 IN IN3327DEN2015 patent/IN2015DN03327A/en unknown
- 2013-10-01 KR KR1020157009515A patent/KR102138393B1/ko not_active Expired - Fee Related
- 2013-10-01 JP JP2015533635A patent/JP6298998B2/ja not_active Expired - Fee Related
- 2013-10-01 CN CN201380050972.5A patent/CN104812747B/zh not_active Expired - Fee Related
- 2013-10-01 SG SG11201502522WA patent/SG11201502522WA/en unknown
- 2013-10-01 AU AU2013326579A patent/AU2013326579B2/en not_active Ceased
- 2013-10-01 BR BR112015007310-7A patent/BR112015007310B1/pt not_active IP Right Cessation
- 2013-10-01 WO PCT/EP2013/070488 patent/WO2014053516A1/en not_active Ceased
- 2013-10-01 CA CA2886630A patent/CA2886630C/en active Active
- 2013-10-01 ES ES13773690.6T patent/ES2616496T3/es active Active
- 2013-10-01 US US14/432,269 patent/US9416114B2/en active Active
- 2013-10-01 UA UAA201504222A patent/UA114644C2/uk unknown
- 2013-10-01 EA EA201500383A patent/EA026236B1/ru not_active IP Right Cessation
- 2013-10-01 NZ NZ706354A patent/NZ706354A/en not_active IP Right Cessation
- 2013-10-01 MX MX2015004160A patent/MX348229B/es active IP Right Grant
- 2013-10-01 MY MYPI2015000804A patent/MY182558A/en unknown
-
2015
- 2015-03-22 IL IL237871A patent/IL237871A/en active IP Right Grant
- 2015-03-30 CL CL2015000787A patent/CL2015000787A1/es unknown
- 2015-03-31 ZA ZA2015/02240A patent/ZA201502240B/en unknown
- 2015-03-31 PH PH12015500724A patent/PH12015500724A1/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HH | Correction or change in general | ||
| FG | Grant or registration |