MX346984B - Métodos para tratar el síndrome de fuga vascular. - Google Patents

Métodos para tratar el síndrome de fuga vascular.

Info

Publication number
MX346984B
MX346984B MX2011007419A MX2011007419A MX346984B MX 346984 B MX346984 B MX 346984B MX 2011007419 A MX2011007419 A MX 2011007419A MX 2011007419 A MX2011007419 A MX 2011007419A MX 346984 B MX346984 B MX 346984B
Authority
MX
Mexico
Prior art keywords
methods
treating vascular
leak syndrome
further disclosed
vascular leak
Prior art date
Application number
MX2011007419A
Other languages
English (en)
Other versions
MX2011007419A (es
Inventor
Robert Shalwitz
Kevin Gene Peters
Original Assignee
Aerpio Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aerpio Therapeutics Inc filed Critical Aerpio Therapeutics Inc
Publication of MX2011007419A publication Critical patent/MX2011007419A/es
Publication of MX346984B publication Critical patent/MX346984B/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Se describen métodos para tratar el Síndrome de Fuga Vascular; además se describen métodos para tratar la fuga vascular debida a enfermedades inflamatorias, inter alia, sepsis, lupus, enfermedad del intestino irritable; se describen aún adicionalmente métodos para tratar el carcinoma de las células renales y el melanoma, se describen todavía adicionalmente métodos para reducir la metástasis de las células malignas y/o prevenir la proliferación de las células del carcinoma vía dispersión debido a la fuga vascular.
MX2011007419A 2009-01-12 2010-01-12 Métodos para tratar el síndrome de fuga vascular. MX346984B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14402209P 2009-01-12 2009-01-12
US18498609P 2009-06-08 2009-06-08
PCT/US2010/020817 WO2010081172A1 (en) 2009-01-12 2010-01-12 Methods for treating vascular leak syndrome

Publications (2)

Publication Number Publication Date
MX2011007419A MX2011007419A (es) 2011-12-16
MX346984B true MX346984B (es) 2017-04-07

Family

ID=42316881

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011007419A MX346984B (es) 2009-01-12 2010-01-12 Métodos para tratar el síndrome de fuga vascular.

Country Status (20)

Country Link
US (6) US20110268694A1 (es)
EP (1) EP2385763B1 (es)
JP (2) JP5558489B2 (es)
KR (1) KR101495950B1 (es)
CN (4) CN108635350A (es)
AU (1) AU2010203352B8 (es)
BR (1) BRPI1006898A2 (es)
CA (2) CA2838846C (es)
DK (1) DK2385763T3 (es)
ES (1) ES2675891T3 (es)
IL (2) IL214047A (es)
MX (1) MX346984B (es)
NZ (1) NZ594535A (es)
PL (1) PL2385763T3 (es)
PT (1) PT2385763T (es)
RU (2) RU2539917C2 (es)
SG (2) SG172312A1 (es)
TR (1) TR201809280T4 (es)
WO (1) WO2010081172A1 (es)
ZA (1) ZA201105679B (es)

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RU2539917C2 (ru) 2015-01-27
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