MX2010003013A - Inhibicion de angiogenesis. - Google Patents

Inhibicion de angiogenesis.

Info

Publication number
MX2010003013A
MX2010003013A MX2010003013A MX2010003013A MX2010003013A MX 2010003013 A MX2010003013 A MX 2010003013A MX 2010003013 A MX2010003013 A MX 2010003013A MX 2010003013 A MX2010003013 A MX 2010003013A MX 2010003013 A MX2010003013 A MX 2010003013A
Authority
MX
Mexico
Prior art keywords
inhibition
angiogenesis
tumor
antagonists
antibodies
Prior art date
Application number
MX2010003013A
Other languages
English (en)
Inventor
Farbod Shojaei
Cuiling Zhong
Napoleon Ferrara
Xiumin Wu
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2010003013A publication Critical patent/MX2010003013A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243—Colony Stimulating Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Abstract

La presente invención es concerniente en general con la inhibición de angiogénesis moderada por células inflamatoria. En particular, la invención es concerniente con la prevención o tratamiento de angiogénesis de tumor y la inhibición de desarrollo del tumor mediante el uso de antagonistas de Bv8, tales como anticuerpos anti-Bv8.
MX2010003013A 2007-09-21 2008-09-19 Inhibicion de angiogenesis. MX2010003013A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97438207P 2007-09-21 2007-09-21
US8307108P 2008-07-23 2008-07-23
PCT/US2008/076954 WO2009039337A2 (en) 2007-09-21 2008-09-19 Inhibition of angiogenesis

Publications (1)

Publication Number Publication Date
MX2010003013A true MX2010003013A (es) 2010-08-02

Family

ID=40030248

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010003013A MX2010003013A (es) 2007-09-21 2008-09-19 Inhibicion de angiogenesis.

Country Status (20)

Country Link
US (1) US9284369B2 (es)
EP (1) EP2203479B1 (es)
JP (1) JP5615709B2 (es)
KR (1) KR101578945B1 (es)
CN (1) CN102037015B (es)
AR (1) AR068532A1 (es)
AU (1) AU2008302214B2 (es)
CA (1) CA2700276A1 (es)
CL (1) CL2008002782A1 (es)
CO (1) CO6270370A2 (es)
ES (1) ES2568881T3 (es)
HK (1) HK1141538A1 (es)
IL (1) IL204502A (es)
MX (1) MX2010003013A (es)
NZ (1) NZ584787A (es)
PE (1) PE20091197A1 (es)
RU (2) RU2471498C2 (es)
TW (1) TWI457349B (es)
WO (1) WO2009039337A2 (es)
ZA (1) ZA201001868B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101008734B1 (ko) * 2001-08-29 2011-01-14 제넨테크, 인크. 유사분열촉진 활성을 가진 Ｂｖ８ 핵산 및 폴리펩티드
EP2526960A1 (en) 2003-03-12 2012-11-28 Genentech, Inc. Use of BV8 and/or EG-VEGF to promote hematopoiesis
WO2008109377A1 (en) * 2007-03-02 2008-09-12 Mdrna, Inc. Nucleic acid compounds for inhibiting vegf family gene expression and uses thereof
US20110027275A1 (en) 2009-07-31 2011-02-03 Napoleone Ferrara Inhibition of tumor metastasis
ES2743558T3 (es) 2009-10-14 2020-02-19 Humanigen Inc Anticuerpos de-EphA3
CA2784385A1 (en) * 2009-12-23 2011-06-30 Genentech, Inc. Anti-bv8 antibodies and uses thereof
US9375473B2 (en) 2010-02-19 2016-06-28 Cornell Research Foundation, Inc. Method to treat autoimmune demyelinating diseases and other autoimmune or inflammatory diseases
KR20140068877A (ko) * 2011-08-17 2014-06-09 제넨테크, 인크. 불응성 종양에서의 혈관신생의 억제
WO2013082511A1 (en) 2011-12-02 2013-06-06 Genentech, Inc. Methods for overcoming tumor resistance to vegf antagonists
US20150118215A1 (en) * 2012-03-30 2015-04-30 The General Hospital Corporation Methods of Inhibiting Cell Proliferation
TWI498425B (zh) * 2013-01-08 2015-09-01 Nat Univ Tsing Hua 層析濾紙型酵素連結免疫吸附分析法
WO2014159923A1 (en) * 2013-03-13 2014-10-02 Health Research, Inc. Enhancement of vaccines
CN105848667B (zh) * 2013-11-22 2020-05-19 珍白斯凯尔有限公司 具有血管生成抑制活性的肽和包含所述肽的组合物
CN104237223B (zh) * 2014-10-08 2017-04-12 江苏奥赛康药业股份有限公司 测定铁‑碳水化合物络合物中不稳定铁含量的方法
CN104587469A (zh) * 2015-01-19 2015-05-06 马洁 G-csf拮抗剂在治疗慢性炎症、预防炎症相关肿瘤中的应用
CN108699562B (zh) * 2015-12-03 2022-04-22 财团法人卫生研究院 异质双聚体型血管内皮生长因子及其应用
WO2018108862A1 (en) * 2016-12-12 2018-06-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Antagonist of prokineticin receptor 2 for use as a medicament for treating an eg-vegf-related cancer
PL3717011T3 (pl) * 2017-11-29 2023-03-27 Csl Limited Sposób leczenia lub zapobiegania uszkodzeniu niedokrwienno- reperfuzyjnemu
CN116059318A (zh) 2018-01-26 2023-05-05 加利福尼亚大学董事会 用于使用抗vegf剂治疗血管生成病症的方法和组合物
WO2021108255A1 (en) 2019-11-25 2021-06-03 The Regents Of The University Of California Long-acting vegf inhibitors for intraocular neovascularization

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9704545D0 (sv) * 1997-12-05 1997-12-05 Astra Pharma Prod Novel compounds
KR101008734B1 (ko) * 2001-08-29 2011-01-14 제넨테크, 인크. 유사분열촉진 활성을 가진 Ｂｖ８ 핵산 및 폴리펩티드
US7323479B2 (en) * 2002-05-17 2008-01-29 Celgene Corporation Methods for treatment and management of brain cancer using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline
CN1802169A (zh) * 2003-03-12 2006-07-12 健泰科生物技术公司 Bv8和/或EG－VEGF促进造血的用途
EP2526960A1 (en) * 2003-03-12 2012-11-28 Genentech, Inc. Use of BV8 and/or EG-VEGF to promote hematopoiesis
CN1829741A (zh) * 2003-05-30 2006-09-06 健泰科生物技术公司 利用抗－vegf抗体的治疗
EP1924603A2 (en) * 2005-09-13 2008-05-28 Zymogenetics, Inc. Prok2 antagonists and methods of use
ITRM20070182A1 (it) * 2007-04-03 2008-10-04 Univ Roma Antagonisti dei recettori delle prochineticine derivati di essi e loro uso

Also Published As

Publication number Publication date
JP5615709B2 (ja) 2014-10-29
CN102037015B (zh) 2016-02-03
NZ584787A (en) 2012-12-21
KR101578945B1 (ko) 2015-12-21
ZA201001868B (en) 2011-06-29
CO6270370A2 (es) 2011-04-20
CL2008002782A1 (es) 2009-07-31
US9284369B2 (en) 2016-03-15
CA2700276A1 (en) 2009-03-26
EP2203479B1 (en) 2016-01-27
KR20100075513A (ko) 2010-07-02
WO2009039337A2 (en) 2009-03-26
IL204502A (en) 2015-05-31
RU2010115755A (ru) 2011-10-27
US20100316633A1 (en) 2010-12-16
ES2568881T3 (es) 2016-05-05
EP2203479A2 (en) 2010-07-07
JP2010540449A (ja) 2010-12-24
CN102037015A (zh) 2011-04-27
TW200920750A (en) 2009-05-16
TWI457349B (zh) 2014-10-21
PE20091197A1 (es) 2009-08-14
HK1141538A1 (zh) 2010-11-12
AU2008302214A1 (en) 2009-03-26
WO2009039337A3 (en) 2009-05-14
AU2008302214B2 (en) 2012-10-25
RU2012140185A (ru) 2014-03-27
RU2471498C2 (ru) 2013-01-10
AR068532A1 (es) 2009-11-18

Similar Documents

Publication Publication Date Title
MX2010003013A (es) Inhibicion de angiogenesis.
MX2012001306A (es) Inhibicion de matastasis de tumor.
IN2012DN03883A (es)
MX2011009539A (es) 2-acetamido-5-aril-1,2,4-triazolonas sustituidas y su uso.
MX354099B (es) Antagonistas de activina-actriia y usos para tratar o prevenir cancer de mama.
MY161495A (en) Virus like particle compositions and methods of use
JO2931B1 (en) Double-substituted phthalazin compounds as antagonists of the cell-specific factor pathway
EA201200473A1 (ru) Замещенные (гетероарилметил)тиогидантоины
MX2010006823A (es) Metodos para el tratamiento de la gota.
MX2019000225A (es) Composiciones y metodos para el tratamiento de enfermedades autoinmunes y otras enfermedades.
WO2012088266A3 (en) Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
IN2012DN02046A (es)
MY172372A (en) Compositions and methods for lowering triglycerides
MY160399A (en) Compounds, compositions, and methods for preventing metastasis of cancer cells
MX345909B (es) Anticuerpos anti-fgfr3 y métodos que los utilizan.
MX2011014019A (es) Derivados de diazahomoadamantano y sus metodos de uso.
WO2012170776A3 (en) Methods of determining a patient's prognosis for recurrence of prostate cancer and/or determining a course of treatment for prostate cancer following a radical prostatectomy
MX2010006933A (es) Composiciones y metodos para reducir o prevenir la deshidratación de la piel.
WO2011130164A3 (en) Unconjugated anti-tfr antibodies and compositions thereof for the treatment of cancer
UA102250C2 (ru) Двухзамещенные фталазины - антагонисты проводящего пути hedgehog
IN2012DN02624A (es)
JO3437B1 (ar) أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها
TN2011000166A1 (en) Disubstituted phthalazine hedgehog pathway antagonists
MX2009012421A (es) Inhibicion de metastasis de tumor por anticuerpos anti neuropilina 2.
PH12013502194A1 (en) Antibodies to egfl7 and methods for their use

Legal Events

Date Code Title Description
FG Grant or registration