MX338975B - Composicion farmaceutica que contiene sales de citrato y bicarbonato, y su uso para el tratamiento de la cistinuria. - Google Patents

Composicion farmaceutica que contiene sales de citrato y bicarbonato, y su uso para el tratamiento de la cistinuria.

Info

Publication number
MX338975B
MX338975B MX2013005482A MX2013005482A MX338975B MX 338975 B MX338975 B MX 338975B MX 2013005482 A MX2013005482 A MX 2013005482A MX 2013005482 A MX2013005482 A MX 2013005482A MX 338975 B MX338975 B MX 338975B
Authority
MX
Mexico
Prior art keywords
pharmaceutical composition
citrate
tablet
bicarbonate salts
oral pharmaceutical
Prior art date
Application number
MX2013005482A
Other languages
English (en)
Other versions
MX2013005482A (es
Inventor
Catherine Guittet
Luc-André Granier
Caroline Roussel-Maupetit
Original Assignee
Advicenne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44146941&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX338975(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Advicenne filed Critical Advicenne
Publication of MX2013005482A publication Critical patent/MX2013005482A/es
Publication of MX338975B publication Critical patent/MX338975B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/745—Polymers of hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Una composición farmacéutica sólida de uso oral bajo la forma de comprimidos que contiene: - una primera formulación farmacéutica oral sólida en forma de al menos un micro-comprimido, el micro-comprimido presenta un núcleo que contiene como ingrediente activo, al menos una sal precursora del ciclo de Krebs como principio activo, y un recubrimiento que contiene al menos un agente de recubrimiento, y - una segunda formulación farmacéutica para uso oral en la forma de al menos un mini-comprimido, el mini-comprimido consiste de un núcleo, que contiene al menos una sal de bicarbonato como un ingrediente activo, como ingrediente activo y al menos una matriz de liberación sostenida, y un recubrimiento que contiene al menos un agente de recubrimiento. Su uso como medicamento, en particular en el tratamiento y/o la prevención de la cistinuria.
MX2013005482A 2010-11-18 2011-11-18 Composicion farmaceutica que contiene sales de citrato y bicarbonato, y su uso para el tratamiento de la cistinuria. MX338975B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1059474A FR2967578B1 (fr) 2010-11-18 2010-11-18 Composition pharmaceutique comportant des sels de citrate et de bicarbonate, et son utilisation pour le traitement de la cystinurie
PCT/FR2011/052697 WO2012066257A1 (fr) 2010-11-18 2011-11-18 Composition pharmaceutique comportant des sels de citrate et de bicarbonate, et son utilisation pour le traitement de la cystinurie

Publications (2)

Publication Number Publication Date
MX2013005482A MX2013005482A (es) 2013-08-29
MX338975B true MX338975B (es) 2016-05-06

Family

ID=44146941

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013005482A MX338975B (es) 2010-11-18 2011-11-18 Composicion farmaceutica que contiene sales de citrato y bicarbonato, y su uso para el tratamiento de la cistinuria.

Country Status (16)

Country Link
US (1) US9636304B2 (es)
EP (1) EP2640363B1 (es)
JP (1) JP5879359B2 (es)
KR (1) KR101699581B1 (es)
AU (1) AU2011331019B2 (es)
CA (1) CA2816660C (es)
DK (1) DK2640363T3 (es)
ES (1) ES2553424T3 (es)
FR (2) FR2967578B1 (es)
HU (1) HUE026230T2 (es)
IL (1) IL226373A (es)
MX (1) MX338975B (es)
NZ (1) NZ611026A (es)
PL (1) PL2640363T3 (es)
WO (1) WO2012066257A1 (es)
ZA (1) ZA201303695B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11273140B2 (en) * 2013-06-06 2022-03-15 Stefanie A. Seixas-Mikelus Juice beverage for prevention and treatment of renal stones
FR3009496B1 (fr) * 2013-08-12 2016-02-05 Mohamed Skiba Formes multiparticulaires a liberation prolongee, procede de leurs preparations et compositions les contenant pour le traitement et/ou prevention de la cyctinurie
US20210145777A1 (en) * 2017-06-16 2021-05-20 Altibio, Inc. Modified-release tiopronin compositions, kits and methods for treating cystinuria and related disorders
AU2022333240A1 (en) 2021-08-24 2024-03-28 Laminaria Group Ab Sodium bicarbonate nutritional supplement

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903255A (en) * 1971-05-17 1975-09-02 Rohm & Haas Effervescent potassium chloride tablet
HU165181B (es) 1971-11-08 1974-07-27
US4451454A (en) * 1981-06-16 1984-05-29 Wong Dennis W Prophylaxis and treatment of thromboembolic disorders in man and in warm-blooded animals with bicarbonate salts of alkali metals
GB2130087A (en) 1982-09-22 1984-05-31 Dr Joachime Helbig Pharmaceutical oral dosage forms of an active agent capable of forming or releasing bicarbonate ions
JPS60197624A (ja) * 1984-03-21 1985-10-07 Nippon Chemiphar Co Ltd 尿アルカリ化性食品組成物
CA1326040C (en) 1989-11-16 1994-01-11 Neill B. Walsdorf Magnesium-potassium citrate
JP2941163B2 (ja) * 1993-02-19 1999-08-25 武田薬品工業株式会社 ペットの尿結石症治療・予防剤および治療方法
US5674529A (en) * 1995-06-06 1997-10-07 Church & Dwight Co., Inc. Alkalinizing potassium salt controlled release preparations
US5888544A (en) * 1996-06-20 1999-03-30 Gerhard Gergely Effervescent system for effervescent tablets and effervescent granules
EP1970066A1 (de) * 2007-03-12 2008-09-17 Medice Arzneimittel Pütter GmbH & Co. KG Pharmazeutische Zusammensetzung zur Behandlung einer Übersäuerung des Blutes

Also Published As

Publication number Publication date
AU2011331019B2 (en) 2016-04-07
JP2013542975A (ja) 2013-11-28
CA2816660C (fr) 2017-07-04
FR21C1049I1 (es) 2021-12-10
ZA201303695B (en) 2014-07-30
FR2967578B1 (fr) 2012-12-28
NZ611026A (en) 2014-12-24
PL2640363T3 (pl) 2016-01-29
FR2967578A1 (fr) 2012-05-25
WO2012066257A1 (fr) 2012-05-24
AU2011331019A1 (en) 2013-06-13
MX2013005482A (es) 2013-08-29
ES2553424T3 (es) 2015-12-09
FR21C1049I2 (fr) 2022-09-30
US20130236545A1 (en) 2013-09-12
JP5879359B2 (ja) 2016-03-08
IL226373A (en) 2016-04-21
KR101699581B1 (ko) 2017-01-24
US9636304B2 (en) 2017-05-02
EP2640363B1 (fr) 2015-08-26
KR20130119450A (ko) 2013-10-31
HUE026230T2 (en) 2016-06-28
IL226373A0 (en) 2013-07-31
EP2640363A1 (fr) 2013-09-25
CA2816660A1 (fr) 2012-05-24
DK2640363T3 (en) 2015-12-14

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