MX337488B - Granulos con alto contenido de ibuprofeno sodico, su preparacion y su uso en preparar formas de dosificacion solidas no efervescentes. - Google Patents

Granulos con alto contenido de ibuprofeno sodico, su preparacion y su uso en preparar formas de dosificacion solidas no efervescentes.

Info

Publication number
MX337488B
MX337488B MX2011000709A MX2011000709A MX337488B MX 337488 B MX337488 B MX 337488B MX 2011000709 A MX2011000709 A MX 2011000709A MX 2011000709 A MX2011000709 A MX 2011000709A MX 337488 B MX337488 B MX 337488B
Authority
MX
Mexico
Prior art keywords
dosage forms
solid dosage
preparation
sodium ibuprofen
high content
Prior art date
Application number
MX2011000709A
Other languages
English (en)
Other versions
MX2011000709A (es
Inventor
Patrick C Hu
Original Assignee
Si Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41259057&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX337488(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Si Group Inc filed Critical Si Group Inc
Publication of MX2011000709A publication Critical patent/MX2011000709A/es
Publication of MX337488B publication Critical patent/MX337488B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Los gránulos de dihidrato de ibuprofeno sódico racémico formados a partir de componentes especificados en la presente, tienen propiedades muy deseables y se pueden usar efectivamente en el equipo de tableteado de prensa rotatoria convencional sin dificultades operacionales frecuentemente encontradas en la práctica actual. Su preparación por un proceso de granulación húmeda, las composiciones de gránulos húmedos, formulaciones adaptadas para la preparación de formas de dosificación sólidas utilizando una prensa rotatoria, formas farmacéuticas sólidas, y métodos para preparar formas farmacéuticas sólidas en una prensa rotatoria también se describen.
MX2011000709A 2008-07-21 2009-07-13 Granulos con alto contenido de ibuprofeno sodico, su preparacion y su uso en preparar formas de dosificacion solidas no efervescentes. MX337488B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8244508P 2008-07-21 2008-07-21
PCT/US2009/050405 WO2010011522A1 (en) 2008-07-21 2009-07-13 High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms

Publications (2)

Publication Number Publication Date
MX2011000709A MX2011000709A (es) 2011-02-24
MX337488B true MX337488B (es) 2016-03-08

Family

ID=41259057

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011000709A MX337488B (es) 2008-07-21 2009-07-13 Granulos con alto contenido de ibuprofeno sodico, su preparacion y su uso en preparar formas de dosificacion solidas no efervescentes.

Country Status (10)

Country Link
US (2) US9629806B2 (es)
EP (1) EP2309988B1 (es)
JP (1) JP5553830B2 (es)
CN (1) CN102099017A (es)
AR (1) AR072826A1 (es)
BR (1) BRPI0916344A2 (es)
CA (1) CA2730005C (es)
CL (1) CL2009001613A1 (es)
MX (1) MX337488B (es)
WO (1) WO2010011522A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0916344A2 (pt) 2008-07-21 2020-07-21 Albemarle Corporation grânulos com alto teor de ibuprofeno de sódio, preparação e utilização para preparação de formas de dosagem sólidas não efervescentes
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
BR112015013945A8 (pt) * 2012-12-14 2019-10-08 Si Group Inc grânulos de alto teor de ibuprofeno de sódio, preparação do mesmo e uso do mesmo na preparação de formas de dosagem sólidas não-efervescentes
KR101890649B1 (ko) * 2013-07-30 2018-09-28 라이온 가부시키가이샤 정제

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US290168A (en) * 1883-12-11 Commode attachment for wash-stands
NL6607516A (es) 1966-05-31 1967-12-01
DE3437599C2 (de) 1984-10-13 1987-04-16 Dolorgiet GmbH & Co KG, 5205 St Augustin Ibuprofen enthaltende Weichgelatinekapseln
US4564697A (en) 1984-11-29 1986-01-14 Ethyl Corporation Halogenated polyol-ester neutralization agent
US5071643A (en) 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
US4806359A (en) 1987-04-22 1989-02-21 Mcneilab, Inc. Iburprofen sustained release matrix and process
US4861797A (en) 1987-10-15 1989-08-29 Oratech Pharmaceutical Development Corporation Liquid ibuprofen compositions and methods of making them
US4859704A (en) 1987-10-15 1989-08-22 Oratech Pharmaceutical Development Corporation Water soluble ibuprofen compositions and methods of making them
DE3838431A1 (de) * 1988-11-12 1990-05-17 Bayer Ag Ibuprofen-brausezubereitungen
US5104648A (en) 1989-02-02 1992-04-14 Mallinckrodt Specialty Chemicals Company High ibuprofen content granulations
GB9019875D0 (en) * 1990-09-11 1990-10-24 Glaxo Group Ltd Pharmaceutical compositions
JP3121080B2 (ja) 1991-12-19 2000-12-25 アール・ピー・シーラー コーポレイション カプセル封入用溶液
ATE180668T1 (de) 1992-12-01 1999-06-15 Spirig Ag S(+)-ibuprofen enthaltende arzneimittel
US5376688A (en) 1992-12-18 1994-12-27 R. P. Scherer Corporation Enhanced solubility pharmaceutical solutions
GB9603699D0 (en) 1996-02-21 1996-04-17 Boots Co Plc Therapeutic composition
IT1293764B1 (it) 1997-07-23 1999-03-10 Chiesi Farma Spa Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua
DE19733505A1 (de) 1997-08-01 1999-02-04 Knoll Ag Schnell wirksames Analgeticum
US6194568B1 (en) * 1998-07-13 2001-02-27 Merck & Co., Inc. Process for synthesizing carbapenem intermediates
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
US6392502B2 (en) * 1998-12-17 2002-05-21 The Whitaker Corporation Balun assembly with reliable coaxial connection
US6340473B1 (en) 1999-07-07 2002-01-22 R.P. Scherer Technologies, Inc. Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same
US6387400B1 (en) 2000-08-29 2002-05-14 R.P. Scherer Technologies, Inc. Process for preparing pharmaceutical compositions for use with soft gelatin formulations
AU2002220248A1 (en) 2000-11-06 2002-05-15 Andrx Pharmaceuticals, Inc. Once a day antihistamine and decongestant formulation
DE20204655U1 (de) * 2002-03-21 2002-06-13 stryker Trauma GmbH, 24232 Schönkirchen Verriegelungsnagel und Zielgerät
CH693586A8 (de) * 2002-10-14 2003-12-15 Roche Consumer Health Ag Darreichungsform von Ibuprofen-Natrium.
US20080020042A1 (en) 2003-10-14 2008-01-24 Peter Gruber Dosage form of sodium ibuprofen
US20050137262A1 (en) 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
JP2005324170A (ja) * 2004-05-17 2005-11-24 Kissei Pharmaceut Co Ltd 振動篩装置及びその運転方法
JP4753567B2 (ja) 2004-11-19 2011-08-24 旭化成ケミカルズ株式会社 付着性の高い薬物を含有する錠剤の製造方法
DE102005009241A1 (de) 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit kontrollierter Bioverfügbarkeit
AU2006226293B2 (en) * 2005-03-22 2011-04-07 Losan Pharma Gmbh Solubilized ibuprofen
EP1800667A1 (en) * 2005-12-23 2007-06-27 Losan Pharma GmbH Rapidly solubilizing ibuprofen granulate
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BRPI0916344A2 (pt) 2008-07-21 2020-07-21 Albemarle Corporation grânulos com alto teor de ibuprofeno de sódio, preparação e utilização para preparação de formas de dosagem sólidas não efervescentes
MX2020011961A (es) 2010-03-24 2022-04-19 Jazz Pharmaceuticals Inc Formas de dosis de liberacion controlada para substancias de farmaco de alta dosis, solubles en agua e higroscopicas.

Also Published As

Publication number Publication date
JP5553830B2 (ja) 2014-07-16
AR072826A1 (es) 2010-09-22
US9629806B2 (en) 2017-04-25
CL2009001613A1 (es) 2010-07-19
CA2730005A1 (en) 2010-01-28
WO2010011522A1 (en) 2010-01-28
CN102099017A (zh) 2011-06-15
EP2309988A1 (en) 2011-04-20
US20110182984A1 (en) 2011-07-28
EP2309988B1 (en) 2015-11-25
CA2730005C (en) 2017-06-13
JP2011528712A (ja) 2011-11-24
US20170181992A1 (en) 2017-06-29
BRPI0916344A2 (pt) 2020-07-21
MX2011000709A (es) 2011-02-24
US10391072B2 (en) 2019-08-27

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Legal Events

Date Code Title Description
GB Transfer or rights

Owner name: SI GROUP, INC.*

FG Grant or registration