MX336242B - Uso de los compuestos a base de lantibioticos del tipo b que tienen actividad antimicrobiana. - Google Patents
Uso de los compuestos a base de lantibioticos del tipo b que tienen actividad antimicrobiana.Info
- Publication number
- MX336242B MX336242B MX2010000492A MX2010000492A MX336242B MX 336242 B MX336242 B MX 336242B MX 2010000492 A MX2010000492 A MX 2010000492A MX 2010000492 A MX2010000492 A MX 2010000492A MX 336242 B MX336242 B MX 336242B
- Authority
- MX
- Mexico
- Prior art keywords
- type
- lantibiotic
- based compounds
- antimicrobial activity
- prophylaxis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invención proporciona métodos para el tratamiento o profilaxis de una infección microbiana del colon o del intestino inferior en un sujeto, el método comprende administrar al sujeto un lantibiótico del tipo B. En particular, la invención proporciona métodos para el tratamiento o profilaxis de una infección provocada por Clostridium difficile. Los lantibióticos del tipo B pueden incluir compuestos seleccionados del grupo que consiste de mersacidina, actagardina, plantaricina, planosporicina, ruminococcina, antibiótico 10789, michiganina y haloduracina, y derivados y variantes de los mismos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0714030.4A GB0714030D0 (en) | 2007-07-18 | 2007-07-18 | The use of type-B lantibiotic-based compounds having antimicrobial activity |
PCT/GB2008/002463 WO2009010763A1 (en) | 2007-07-18 | 2008-07-18 | The use of type-b lantibiotic-based compounds having antimicrobial activity |
Publications (1)
Publication Number | Publication Date |
---|---|
MX336242B true MX336242B (es) | 2016-01-13 |
Family
ID=38476567
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010000492A MX336242B (es) | 2007-07-18 | 2008-07-18 | Uso de los compuestos a base de lantibioticos del tipo b que tienen actividad antimicrobiana. |
Country Status (10)
Country | Link |
---|---|
US (1) | US8575094B2 (es) |
EP (1) | EP2178552A1 (es) |
JP (1) | JP5613563B2 (es) |
CN (1) | CN101754769B (es) |
BR (1) | BRPI0814034A2 (es) |
CA (1) | CA2693047A1 (es) |
EA (1) | EA021628B1 (es) |
GB (1) | GB0714030D0 (es) |
MX (1) | MX336242B (es) |
WO (1) | WO2009010763A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0600928D0 (en) | 2006-01-17 | 2006-02-22 | Novacta Biosystems Ltd | Improvements relating to lantibiotics |
GB0714029D0 (en) | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | Lantibiotic-based compounds having antimicrobial activity |
GB0714030D0 (en) | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | The use of type-B lantibiotic-based compounds having antimicrobial activity |
EA017564B1 (ru) * | 2007-09-12 | 2013-01-30 | Тарганта Терапьютикс Корп. | Способ ингибирования клостридиум диффициле введением оритаванцина |
CA2749278A1 (en) | 2009-01-14 | 2010-07-22 | Novacta Biosystems Limited | Deoxyactagardine derivatives |
KR20110122139A (ko) | 2009-02-04 | 2011-11-09 | 노박타 바이오시스템스 리미티드 | 액타가르딘 유도체 |
FR2954140A1 (fr) * | 2009-12-17 | 2011-06-24 | Oreal | Compositions cosmetiques ou dermatologiques a base de bacteriocines et de prebiotiques |
GB201001688D0 (en) | 2010-02-02 | 2010-03-17 | Novacta Biosystems Ltd | Compounds |
WO2011095768A1 (en) * | 2010-02-02 | 2011-08-11 | Novacta Biosystems Limited | Lantibiotic salts |
US20130171252A1 (en) * | 2010-07-14 | 2013-07-04 | Novacta Biosystems Limited | Formulation Comprising a Type B Lantibiotic |
GB201013513D0 (en) | 2010-08-11 | 2010-09-22 | Novacta Biosystems Ltd | Formulations |
GB201213434D0 (en) | 2012-07-27 | 2012-09-12 | Novacta Biosystems Ltd | The use of type-B lantibiotic-based compounds having antimicrobial activity |
EP3111949A1 (en) * | 2015-07-01 | 2017-01-04 | Deinobiotics | New bicyclic lipopeptide, preparation and use as antimicrobial agent |
CN106366168B (zh) * | 2016-08-26 | 2020-09-15 | 上海交通大学 | 羊毛硫肽类抗菌肽及其脱氢衍生物的制备方法 |
US20210324009A1 (en) * | 2020-04-17 | 2021-10-21 | The University Of Hong Kong | Anti-bacterial calcium-dependent antibiotic (cda) analogs and methods of treating bacterial infections |
WO2023164788A1 (zh) * | 2022-03-01 | 2023-09-07 | 中国科学院深圳理工大学(筹) | 羊毛硫抗生素高通量筛选方法 |
Family Cites Families (37)
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US3710795A (en) * | 1970-09-29 | 1973-01-16 | Alza Corp | Drug-delivery device with stretched, rate-controlling membrane |
GB8507528D0 (en) | 1985-03-22 | 1985-05-01 | Lepetit Spa | Basis monocarboxyamide derivatives |
US5304540A (en) | 1988-06-22 | 1994-04-19 | Applied Microbiology, Inc. | Pharmaceutical bacteriocin compositions and methods for using the same |
IN167138B (es) * | 1988-08-17 | 1990-09-01 | Hoechst India | |
GB8926639D0 (en) | 1989-11-24 | 1990-01-17 | Agricultural & Food Res | Delayed release formulations |
KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
IT1260505B (it) | 1992-06-01 | 1996-04-09 | Poli Ind Chimica Spa | Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon |
IL107887A (en) * | 1992-12-08 | 2003-07-06 | Ambi Inc | Stabilized lanthionine containing bacteriocin compositions |
US5512269A (en) | 1993-06-09 | 1996-04-30 | Burroughs Wellcome, Co. | Method of treating retained pulmonary secretions |
EP0700998B1 (en) * | 1994-09-12 | 2003-11-26 | Aventis Pharma Deutschland GmbH | Recombinant mersacidin and a method for production |
EP0833657B1 (en) * | 1995-06-23 | 2003-08-27 | AMBI Inc. | A method for the control of antibiotic-resistant gram positive bacteria and treatment of infection |
GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
US5985823A (en) * | 1997-06-09 | 1999-11-16 | Ambi Inc. | Method for the treatment of diarrheal disease and for eliminating particular bacterial populations from the colon |
US5958873A (en) | 1997-06-09 | 1999-09-28 | University Of Cincinnati | Oral formulation for treatment of bacteria-induced diseases of the colon |
DE19745583A1 (de) * | 1997-10-15 | 1999-04-22 | Hoechst Marion Roussel De Gmbh | Neues Lantibiotikum verwandt mit Actagardine, Verfahren zur Herstellung und Verwendung derselben |
US6569830B1 (en) * | 1999-03-05 | 2003-05-27 | Ambi, Inc. | Compositions and methods for treatment of staphylococcal infection while suppressing formation of antibiotic-resistant strains |
CN1245974C (zh) * | 2000-06-28 | 2006-03-22 | 特瓦制药工业有限公司 | 卡维地洛 |
PT1294358E (pt) | 2000-06-28 | 2004-12-31 | Smithkline Beecham Plc | Processo de moagem por via humida |
GB0110432D0 (en) | 2001-04-27 | 2001-06-20 | Plant Bioscience Ltd | Lantibiotic production |
WO2002103010A1 (en) | 2001-06-14 | 2002-12-27 | Plant Bioscience Limited | Methods and materials for targeted gene disruption in actinomycete bacteria |
US6861236B2 (en) | 2002-05-24 | 2005-03-01 | Applied Nanosystems B.V. | Export and modification of (poly)peptides in the lantibiotic way |
JP2006502713A (ja) | 2002-10-10 | 2006-01-26 | モリケム メディシンズ, インコーポレイテッド | デュラマイシンをコードする核酸 |
US7351687B2 (en) | 2003-07-18 | 2008-04-01 | Vicuron Pharmaceuticals, Inc. | Antibiotic 107891, its factors A1 and A2, pharmaceutically acceptable salts and compositions, and use thereof |
ES2281808T3 (es) * | 2003-07-18 | 2007-10-01 | Vicuron Pharmaceuticals, Inc. | Antibiotico 107891, sus factores a1 y a2, composiciones y sales farmaceuticamente aceptables y uso del mismo. |
GB0406870D0 (en) | 2004-03-26 | 2004-04-28 | Novacta Biosystems Ltd | Improvements relating to the production of lantibiotics |
WO2007036706A1 (en) * | 2005-09-27 | 2007-04-05 | Novacta Biosystems Limited | Variants of the lantibiotic mersacidin and their use |
US20090170562A1 (en) * | 2005-09-28 | 2009-07-02 | Nokia Corporation | Speed dial configuration of a mobile terminal for a mobile telecommunications network from a remote service |
GB0600928D0 (en) * | 2006-01-17 | 2006-02-22 | Novacta Biosystems Ltd | Improvements relating to lantibiotics |
CA2667167C (en) | 2006-10-27 | 2014-02-18 | Pfizer Products Inc. | Hydroxypropyl methyl cellulose hard capsules and process of manufacture |
WO2008151434A1 (en) | 2007-06-12 | 2008-12-18 | The University Of British Columbia | Small cationic antimicrobial peptides |
GB0714029D0 (en) * | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | Lantibiotic-based compounds having antimicrobial activity |
GB0714030D0 (en) | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | The use of type-B lantibiotic-based compounds having antimicrobial activity |
KR20110086582A (ko) | 2008-11-24 | 2011-07-28 | 센티넬라 파마세티컬즈, 인크. | 항균활성이 강화된 란티바이오틱 카르복시아미드 유도체 |
CA2749278A1 (en) | 2009-01-14 | 2010-07-22 | Novacta Biosystems Limited | Deoxyactagardine derivatives |
GB0900599D0 (en) | 2009-01-14 | 2009-02-18 | Novacta Biosystems Ltd | Treatment |
KR20110122139A (ko) | 2009-02-04 | 2011-11-09 | 노박타 바이오시스템스 리미티드 | 액타가르딘 유도체 |
-
2007
- 2007-07-18 GB GBGB0714030.4A patent/GB0714030D0/en not_active Ceased
-
2008
- 2008-07-18 JP JP2010516581A patent/JP5613563B2/ja not_active Expired - Fee Related
- 2008-07-18 EA EA200971102A patent/EA021628B1/ru not_active IP Right Cessation
- 2008-07-18 CN CN200880024936.0A patent/CN101754769B/zh not_active Expired - Fee Related
- 2008-07-18 WO PCT/GB2008/002463 patent/WO2009010763A1/en active Application Filing
- 2008-07-18 EP EP08775988A patent/EP2178552A1/en not_active Withdrawn
- 2008-07-18 MX MX2010000492A patent/MX336242B/es unknown
- 2008-07-18 BR BRPI0814034-0A2A patent/BRPI0814034A2/pt active Search and Examination
- 2008-07-18 CA CA 2693047 patent/CA2693047A1/en not_active Abandoned
-
2009
- 2009-01-21 US US12/357,077 patent/US8575094B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP2178552A1 (en) | 2010-04-28 |
EA200971102A1 (ru) | 2010-08-30 |
US8575094B2 (en) | 2013-11-05 |
CN101754769A (zh) | 2010-06-23 |
CA2693047A1 (en) | 2009-01-22 |
JP2010533695A (ja) | 2010-10-28 |
GB0714030D0 (en) | 2007-08-29 |
BRPI0814034A2 (pt) | 2015-02-18 |
CN101754769B (zh) | 2015-09-09 |
EA021628B1 (ru) | 2015-07-30 |
US20090203583A1 (en) | 2009-08-13 |
WO2009010763A1 (en) | 2009-01-22 |
JP5613563B2 (ja) | 2014-10-22 |
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