MX2023005878A - Metodos para modular las interacciones de la superficie de la celula huesped con sars-cov-2. - Google Patents

Metodos para modular las interacciones de la superficie de la celula huesped con sars-cov-2.

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Publication number
MX2023005878A
MX2023005878A MX2023005878A MX2023005878A MX2023005878A MX 2023005878 A MX2023005878 A MX 2023005878A MX 2023005878 A MX2023005878 A MX 2023005878A MX 2023005878 A MX2023005878 A MX 2023005878A MX 2023005878 A MX2023005878 A MX 2023005878A
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MX
Mexico
Prior art keywords
cov
methods
sars
host cell
cell surface
Prior art date
Application number
MX2023005878A
Other languages
English (en)
Inventor
Nadia Martinez-Martin
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2023005878A publication Critical patent/MX2023005878A/es

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    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1002—Coronaviridae
    • C07K16/1003—Severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2 or Covid-19]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/165—Coronaviridae, e.g. avian infectious bronchitis virus
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    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Food Science & Technology (AREA)
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  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract

En la presente se proporcionan métodos para tratar o prevenir la infección por SARS-CoV-2 que comprenden modular las interacciones entre la proteína espicular de SARS-CoV-2 y las proteínas de la célula huésped expresadas en la membrana plasmática, así como métodos para identificar moduladores de tales interacciones.
MX2023005878A 2020-11-23 2021-11-23 Metodos para modular las interacciones de la superficie de la celula huesped con sars-cov-2. MX2023005878A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063117440P 2020-11-23 2020-11-23
PCT/US2021/060464 WO2022109441A1 (en) 2020-11-23 2021-11-23 Methods for modulating host cell surface interactions with sars-cov-2

Publications (1)

Publication Number Publication Date
MX2023005878A true MX2023005878A (es) 2023-06-05

Family

ID=79288106

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023005878A MX2023005878A (es) 2020-11-23 2021-11-23 Metodos para modular las interacciones de la superficie de la celula huesped con sars-cov-2.

Country Status (12)

Country Link
US (1) US20240025972A1 (es)
EP (1) EP4247494A1 (es)
JP (1) JP2023554592A (es)
KR (1) KR20230113329A (es)
CN (1) CN117425736A (es)
AU (1) AU2021381455A1 (es)
BR (1) BR112023009875A2 (es)
CA (1) CA3200885A1 (es)
IL (1) IL302935A (es)
MX (1) MX2023005878A (es)
TW (1) TW202237178A (es)
WO (1) WO2022109441A1 (es)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2919890B2 (ja) 1988-11-11 1999-07-19 メディカル リサーチ カウンスル 単一ドメインリガンド、そのリガンドからなる受容体、その製造方法、ならびにそのリガンドおよび受容体の使用
US6335155B1 (en) 1998-06-26 2002-01-01 Sunesis Pharmaceuticals, Inc. Methods for rapidly identifying small organic molecule ligands for binding to biological target molecules
JP2002533726A (ja) 1998-12-28 2002-10-08 サネシス ファーマシューティカルス インコーポレイテッド 結合のための小有機分子リガンドの同定
AT506258A1 (de) 2007-12-18 2009-07-15 Apeiron Biolog Forschungs Und Behandlung inflammatorischer krankheiten
CN102245376A (zh) 2008-12-09 2011-11-16 Sca卫生用品公司 带有光栅压花的纤维制品及其制造方法
JP6456356B2 (ja) 2013-03-15 2019-01-23 ジェネンテック， インコーポレイテッド ＩＬ−２２ポリペプチド及びＩＬ−２２Ｆｃ融合タンパク質並びに使用方法
WO2016008051A1 (en) * 2014-07-15 2016-01-21 Mcmaster University Contactin-1 (cntn1) for use in methods of diagnosis and treatment of prostate cancer
TWI698444B (zh) 2014-10-29 2020-07-11 美商基利科學股份有限公司 製備核糖苷的方法
US10443049B2 (en) 2017-01-24 2019-10-15 Northwestern University Active low molecular weight variants of angiotensin converting enzyme 2 (ACE2)
KR20210134300A (ko) * 2020-04-02 2021-11-09 리제너론 파아마슈티컬스, 인크. 항-sars-cov-2 스파이크 당단백질 항체 및 항원-결합 단편

Also Published As

Publication number Publication date
TW202237178A (zh) 2022-10-01
US20240025972A1 (en) 2024-01-25
KR20230113329A (ko) 2023-07-28
CN117425736A (zh) 2024-01-19
CA3200885A1 (en) 2022-05-27
WO2022109441A1 (en) 2022-05-27
BR112023009875A2 (pt) 2024-02-06
AU2021381455A1 (en) 2023-06-29
IL302935A (en) 2023-07-01
JP2023554592A (ja) 2023-12-28
EP4247494A1 (en) 2023-09-27

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