MX2022016388A - Compuestos de piperidina sustituida y su uso. - Google Patents

Compuestos de piperidina sustituida y su uso.

Info

Publication number
MX2022016388A
MX2022016388A MX2022016388A MX2022016388A MX2022016388A MX 2022016388 A MX2022016388 A MX 2022016388A MX 2022016388 A MX2022016388 A MX 2022016388A MX 2022016388 A MX2022016388 A MX 2022016388A MX 2022016388 A MX2022016388 A MX 2022016388A
Authority
MX
Mexico
Prior art keywords
application
piperidine compound
substituted piperidine
iii
compounds
Prior art date
Application number
MX2022016388A
Other languages
English (en)
Spanish (es)
Inventor
Keiichi Sorimachi
Takafumi Motoki
Yu Yoshida
Makoto Kotake
Yoichi Kita
Toshiyuki OHFUSA
Taro ASABA
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of MX2022016388A publication Critical patent/MX2022016388A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pain & Pain Management (AREA)
MX2022016388A 2020-07-17 2021-07-15 Compuestos de piperidina sustituida y su uso. MX2022016388A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020122864 2020-07-17
PCT/JP2021/026649 WO2022014680A1 (ja) 2020-07-17 2021-07-15 置換ピペリジン化合物及びその用途

Publications (1)

Publication Number Publication Date
MX2022016388A true MX2022016388A (es) 2023-01-30

Family

ID=79291962

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022016388A MX2022016388A (es) 2020-07-17 2021-07-15 Compuestos de piperidina sustituida y su uso.

Country Status (19)

Country Link
US (1) US11479552B2 (cg-RX-API-DMAC7.html)
EP (1) EP4151277A4 (cg-RX-API-DMAC7.html)
JP (1) JP7190612B2 (cg-RX-API-DMAC7.html)
KR (1) KR20230040953A (cg-RX-API-DMAC7.html)
CN (3) CN115884971B (cg-RX-API-DMAC7.html)
AR (1) AR122973A1 (cg-RX-API-DMAC7.html)
AU (1) AU2021308053A1 (cg-RX-API-DMAC7.html)
BR (1) BR112022026161A2 (cg-RX-API-DMAC7.html)
CA (1) CA3187835A1 (cg-RX-API-DMAC7.html)
CL (1) CL2022003666A1 (cg-RX-API-DMAC7.html)
CO (1) CO2022018446A2 (cg-RX-API-DMAC7.html)
IL (1) IL299125B1 (cg-RX-API-DMAC7.html)
MX (1) MX2022016388A (cg-RX-API-DMAC7.html)
PE (1) PE20231103A1 (cg-RX-API-DMAC7.html)
PH (1) PH12022553488A1 (cg-RX-API-DMAC7.html)
TW (1) TWI888599B (cg-RX-API-DMAC7.html)
UA (1) UA129636C2 (cg-RX-API-DMAC7.html)
WO (1) WO2022014680A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA202213562B (cg-RX-API-DMAC7.html)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK4065585T3 (da) 2019-11-25 2025-09-08 Alkermes Inc Substituerede makrocykliske forbindelser og relaterede behandlingsfremgangsmåder
US11760747B2 (en) 2020-12-21 2023-09-19 Alkermes, Inc. Substituted piperidino compounds and related methods of treatment
US12006330B2 (en) 2020-12-21 2024-06-11 Alkermes, Inc. Substituted macrocyclic compounds and related methods of treatment
JP7591592B2 (ja) * 2022-01-14 2024-11-28 エーザイ・アール・アンド・ディー・マネジメント株式会社 置換ピペリジン化合物を含有する医薬
CN118451076A (zh) * 2022-01-14 2024-08-06 卫材R&D管理有限公司 经取代的哌啶化合物的晶体、经取代的哌啶化合物的盐及其晶体
TW202423404A (zh) * 2022-10-07 2024-06-16 日商橘生藥品工業股份有限公司 環戊烷化合物
TW202432109A (zh) * 2022-10-31 2024-08-16 日商武田藥品工業股份有限公司 食慾素2型受體促效劑之給藥
KR20250112793A (ko) 2022-12-16 2025-07-24 다이이찌 산쿄 가부시키가이샤 2-아자비시클로[3.1.1]헵탄 화합물
TW202502342A (zh) 2023-06-02 2025-01-16 日商武田藥品工業股份有限公司 食慾素2受體促效劑用於改善睡眠期間之呼吸功能的用途
WO2025124698A1 (en) 2023-12-12 2025-06-19 Idorsia Pharmaceuticals Ltd Aryl sulfone and sulfanone derivatives as orexin receptor modulators
WO2025132542A1 (en) 2023-12-19 2025-06-26 Idorsia Pharmaceuticals Ltd Macrocyclic orexin agonists
WO2025137359A1 (en) 2023-12-20 2025-06-26 Eisai R&D Management Co., Ltd. Assay methods to identify a disease
WO2025229493A1 (en) 2024-04-29 2025-11-06 Takeda Pharmaceutical Company Limited Dosing of orexin type 2 receptor agonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG34208A1 (en) 1995-03-01 1996-12-06 Guy Andrew Vaz Blast and fragment resistant polyurethane boot sole for safety footwear
WO1996034877A1 (en) 1995-05-05 1996-11-07 Human Genome Sciences, Inc. Human neuropeptide receptor
US6309854B1 (en) 1996-12-17 2001-10-30 Smithkline Beecham Corporation Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72
US6159605A (en) 1997-02-18 2000-12-12 Dainichiseika Color & Chemicals Mfg. Co., Ltd. Ink-jet recording sheet
US6020157A (en) 1997-04-30 2000-02-01 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72X receptor
US5935814A (en) 1997-04-30 1999-08-10 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72Y receptor
US6166193A (en) 1997-07-25 2000-12-26 Board Of Regents, University Of Texas System Polynucleotides encoding MY1 receptor
KR100327888B1 (ko) 1999-07-14 2002-03-09 정숭렬 도로포장 파손촉진 시험장치의 무선제어 시스템
US7547693B2 (en) 2003-09-22 2009-06-16 Banyu Pharmaceutical Co. Ltd. Piperidine derivative
MX2007004269A (es) 2004-10-20 2007-06-15 Neurosearch As Derivados de arilo diazabiciclico nuevos y su uso medico.
JP2009184924A (ja) 2006-05-31 2009-08-20 Eisai R & D Management Co Ltd 生物学的試薬用化合物
TW201444849A (zh) * 2013-03-13 2014-12-01 Janssen Pharmaceutica Nv 經取代的7-氮雜雙環類及其作為食慾激素受體調節劑之用途

Also Published As

Publication number Publication date
CL2022003666A1 (es) 2023-05-26
CN119235864A (zh) 2025-01-03
US20220017517A1 (en) 2022-01-20
AR122973A1 (es) 2022-10-19
EP4151277A1 (en) 2023-03-22
CN119258067A (zh) 2025-01-07
CN115884971A (zh) 2023-03-31
UA129636C2 (uk) 2025-06-18
CA3187835A1 (en) 2022-01-20
KR20230040953A (ko) 2023-03-23
IL299125A (en) 2023-02-01
BR112022026161A2 (pt) 2023-01-31
PH12022553488A1 (en) 2024-04-22
US11479552B2 (en) 2022-10-25
WO2022014680A1 (ja) 2022-01-20
CN115884971B (zh) 2024-11-05
TWI888599B (zh) 2025-07-01
JPWO2022014680A1 (cg-RX-API-DMAC7.html) 2022-01-20
IL299125B1 (en) 2025-11-01
EP4151277A4 (en) 2024-06-26
PE20231103A1 (es) 2023-07-19
AU2021308053A1 (en) 2023-02-02
JP7190612B2 (ja) 2022-12-15
TW202216705A (zh) 2022-05-01
CO2022018446A2 (es) 2023-03-07
ZA202213562B (en) 2023-10-25

Similar Documents

Publication Publication Date Title
MX2022016388A (es) Compuestos de piperidina sustituida y su uso.
ZA202400395B (en) Novel aryl ether substituted heterocyclic compound as glp1r agonist
MY209784A (en) Heterocyclic compound and use thereof
ZA202201503B (en) Urea compound for antagonizing lpa1 receptor
MX2022006783A (es) Nuevos derivados de metilquinazolinona.
PH12020500236A1 (en) Heterocyclic compund and use thereof
EP4438041A3 (en) Substituted piperidine compound and use thereof
IS6902A (is) N-setin heterósýklísk NMDA/NR2B mótlyf sem ekki eru arýl
PH12022551571A1 (en) Protein degradation agent compound preparation method and application
MXPA04010625A (es) Antagonista de receptor de taquicinina.
MY194676A (en) Sulfonamide compound or salt thereof
MX2024000230A (es) Inhibidores de cdk2.
PH12016502358B1 (en) Novel pyrrolidine compound and application as melanocortin receptor agonist
CR20240014A (es) Pirimidinil-pirazoles sustituidos como inhibidores de cdk2
WO2023199091A8 (en) Heterocyclic compound
MX2025004831A (es) Compuesto heterociclico
MX2022006653A (es) Compuestos para modular la actividad de fxr y usos de los mismos.
EA200700365A1 (ru) Производные индол-2-карбоксамидина как антагонисты nmda рецептора
NO20080165L (no) Alfa-(aryl-OR heteroaryl-metyl)-beta piperidinopropanamidforbindelser som ORL1-receptorantagonister
MX379576B (es) Derivados de azetidina
MX2022004215A (es) Derivados de 2-azaespiro[3.4]octano como agonistas de m4.
CR20220141A (es) Derivados de 2-azaspiro[3,4]octano como agonistas de m4
PH12021552787A1 (en) Tetracyclic compounds as cdc7 inhibitors
PH12021551989A1 (en) Pharmaceutical composition comprising benzimidazole derivative compound
TW200643019A (en) Optically active tetrahydronaphthalene derivative