MX2022013416A - Polipeptidos de fusion para la produccion de peptidos objetivo. - Google Patents

Polipeptidos de fusion para la produccion de peptidos objetivo.

Info

Publication number
MX2022013416A
MX2022013416A MX2022013416A MX2022013416A MX2022013416A MX 2022013416 A MX2022013416 A MX 2022013416A MX 2022013416 A MX2022013416 A MX 2022013416A MX 2022013416 A MX2022013416 A MX 2022013416A MX 2022013416 A MX2022013416 A MX 2022013416A
Authority
MX
Mexico
Prior art keywords
fusion polypeptides
target peptide
peptide production
nucleic acid
acid molecules
Prior art date
Application number
MX2022013416A
Other languages
English (en)
Inventor
Christoph Kutzner
Original Assignee
Christoph Kutzner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Christoph Kutzner filed Critical Christoph Kutzner
Publication of MX2022013416A publication Critical patent/MX2022013416A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43572—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from bees
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Insects & Arthropods (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a polipéptidos de fusión, a moléculas de ácidos nucleicos que codifican tales polipéptidos de fusión y a células modificadas genéticamente que comprenden tales moléculas de ácidos nucleicos. Además, la presente invención se refiere a un método para preparar un péptido objetivo y mezclas de péptidos objetivo.
MX2022013416A 2020-04-27 2021-04-27 Polipeptidos de fusion para la produccion de peptidos objetivo. MX2022013416A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20171573.7A EP3904525A1 (en) 2020-04-27 2020-04-27 Fusion polypeptides for target peptide production
PCT/EP2021/060892 WO2021219585A2 (en) 2020-04-27 2021-04-27 Fusion polypeptides for target peptide production

Publications (1)

Publication Number Publication Date
MX2022013416A true MX2022013416A (es) 2023-01-19

Family

ID=70480080

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022013416A MX2022013416A (es) 2020-04-27 2021-04-27 Polipeptidos de fusion para la produccion de peptidos objetivo.

Country Status (7)

Country Link
US (1) US20230203109A1 (es)
EP (2) EP3904525A1 (es)
CN (1) CN115605604A (es)
CA (1) CA3180878A1 (es)
DE (1) DE202021004299U1 (es)
MX (1) MX2022013416A (es)
WO (1) WO2021219585A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4303305A1 (en) * 2022-07-07 2024-01-10 Kutzner, Christoph Fusion polypeptides for cell penetration and cell targeting
WO2024092199A1 (en) * 2022-10-27 2024-05-02 Epicrispr Biotechnologies, Inc. Systems and compositions for fusion polypeptides and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2326442C (en) * 1998-04-01 2010-05-18 Danisco A/S Non-maltogenic exoamylases and their use in retarding retrogradation of starch
WO2006113957A2 (en) 2005-04-26 2006-11-02 Sandoz Ag Production of recombinant proteins by autoproteolytic cleavage of a fusion protein
AU2011253661B2 (en) 2005-04-26 2013-06-13 Boehringer Ingelheim Rcv Gmbh & Co Kg Production of recombinant proteins by autoproteolytic cleavage of a fusion protein
CN101605809A (zh) 2006-10-31 2009-12-16 善笙生物科技股份有限公司 淀粉吸附区域及其用途
EP2746390A1 (en) 2012-12-19 2014-06-25 Sandoz Ag Method for producing a recombinant protein of interest
DE102018200602A1 (de) 2018-01-15 2019-07-18 Technische Universität München Biologische Synthese von Aminosäureketten zur Herstellung von Peptiden und Proteinen

Also Published As

Publication number Publication date
CN115605604A (zh) 2023-01-13
EP4143331A2 (en) 2023-03-08
US20230203109A1 (en) 2023-06-29
CA3180878A1 (en) 2021-11-04
WO2021219585A3 (en) 2021-12-16
WO2021219585A2 (en) 2021-11-04
EP3904525A1 (en) 2021-11-03
DE202021004299U1 (de) 2023-10-13

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