MX2022006014A - Ganaxolona para uso en el tratamiento del complejo de esclerosis tuberosa. - Google Patents

Ganaxolona para uso en el tratamiento del complejo de esclerosis tuberosa.

Info

Publication number
MX2022006014A
MX2022006014A MX2022006014A MX2022006014A MX2022006014A MX 2022006014 A MX2022006014 A MX 2022006014A MX 2022006014 A MX2022006014 A MX 2022006014A MX 2022006014 A MX2022006014 A MX 2022006014A MX 2022006014 A MX2022006014 A MX 2022006014A
Authority
MX
Mexico
Prior art keywords
tuberous sclerosis
sclerosis complex
ganaxolone
treating
treating tuberous
Prior art date
Application number
MX2022006014A
Other languages
English (en)
Inventor
Joseph Hulihan
Alex Aimetti
Scott Braunstein
Original Assignee
Marinus Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marinus Pharmaceuticals Inc filed Critical Marinus Pharmaceuticals Inc
Publication of MX2022006014A publication Critical patent/MX2022006014A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Abstract

La descripción de métodos para tratar el complejo de esclerosis tuberosa o la epilepsia relacionada con el complejo de esclerosis tuberosa, que comprende administrar a un sujeto que lo necesite una cantidad terapéuticamente eficaz de un neuroesteroide de pregnenolona farmacéuticamente aceptable, tal como ganaxolona, para reducir uno o más síntomas del complejo de esclerosis tuberosa o epilepsia relacionada con el complejo de esclerosis tuberosa.
MX2022006014A 2019-12-06 2020-12-07 Ganaxolona para uso en el tratamiento del complejo de esclerosis tuberosa. MX2022006014A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962944549P 2019-12-06 2019-12-06
PCT/US2020/063648 WO2021113834A1 (en) 2019-12-06 2020-12-07 Ganaxolone for use in treating tuberous sclerosis complex

Publications (1)

Publication Number Publication Date
MX2022006014A true MX2022006014A (es) 2022-06-22

Family

ID=76221243

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022006014A MX2022006014A (es) 2019-12-06 2020-12-07 Ganaxolona para uso en el tratamiento del complejo de esclerosis tuberosa.

Country Status (10)

Country Link
US (2) US11701367B2 (es)
EP (1) EP4072559A4 (es)
JP (1) JP2023503928A (es)
KR (1) KR20220134529A (es)
CN (1) CN114828889A (es)
AU (1) AU2020395254A1 (es)
CA (1) CA3158280A1 (es)
IL (1) IL293525A (es)
MX (1) MX2022006014A (es)
WO (1) WO2021113834A1 (es)

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Also Published As

Publication number Publication date
EP4072559A4 (en) 2023-06-21
JP2023503928A (ja) 2023-02-01
CN114828889A (zh) 2022-07-29
US20240100067A1 (en) 2024-03-28
CA3158280A1 (en) 2021-06-10
WO2021113834A1 (en) 2021-06-10
EP4072559A1 (en) 2022-10-19
IL293525A (en) 2022-08-01
US20220211723A1 (en) 2022-07-07
KR20220134529A (ko) 2022-10-05
US11701367B2 (en) 2023-07-18
AU2020395254A1 (en) 2022-06-02

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