MX2022005229A - Un nuevo proceso eficaz para la sintesis de 2-amino-5-cloro-n,3-di metilbenzamida. - Google Patents
Un nuevo proceso eficaz para la sintesis de 2-amino-5-cloro-n,3-di metilbenzamida.Info
- Publication number
- MX2022005229A MX2022005229A MX2022005229A MX2022005229A MX2022005229A MX 2022005229 A MX2022005229 A MX 2022005229A MX 2022005229 A MX2022005229 A MX 2022005229A MX 2022005229 A MX2022005229 A MX 2022005229A MX 2022005229 A MX2022005229 A MX 2022005229A
- Authority
- MX
- Mexico
- Prior art keywords
- chloro
- amino
- methylbenzamide
- synthesis
- effective process
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/10—Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
- C07C249/08—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
- C07C249/12—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reactions not involving the formation of oxyimino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C251/36—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962929138P | 2019-11-01 | 2019-11-01 | |
| PCT/US2020/057726 WO2021086957A1 (en) | 2019-11-01 | 2020-10-28 | An efficient new process for synthesis of 2-amino-5-chloro-n-,3-dimethylbenzamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022005229A true MX2022005229A (es) | 2022-06-08 |
Family
ID=73543326
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022005229A MX2022005229A (es) | 2019-11-01 | 2020-10-28 | Un nuevo proceso eficaz para la sintesis de 2-amino-5-cloro-n,3-di metilbenzamida. |
| MX2026001742A MX2026001742A (es) | 2019-11-01 | 2022-04-29 | Un nuevo proceso eficaz para la sintesis de 2-amino-5-cloro-n,3-dimetilbenzamida |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2026001742A MX2026001742A (es) | 2019-11-01 | 2022-04-29 | Un nuevo proceso eficaz para la sintesis de 2-amino-5-cloro-n,3-dimetilbenzamida |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11542241B2 (https=) |
| EP (2) | EP3976583B1 (https=) |
| JP (3) | JP7730309B2 (https=) |
| KR (1) | KR20220091537A (https=) |
| CN (3) | CN114080388A (https=) |
| AU (1) | AU2020372895A1 (https=) |
| BR (1) | BR112022008061A2 (https=) |
| HU (1) | HUE067805T2 (https=) |
| IL (3) | IL313390A (https=) |
| MA (1) | MA56056A (https=) |
| MX (2) | MX2022005229A (https=) |
| PL (1) | PL3976583T3 (https=) |
| TW (2) | TWI881549B (https=) |
| WO (1) | WO2021086957A1 (https=) |
| ZA (2) | ZA202204803B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112022008061A2 (pt) * | 2019-11-01 | 2022-07-12 | Fmc Corp | Processo eficaz para síntese de 2-amino-5-cloro-n,3-dimetilbenzamida |
| WO2023073502A1 (en) * | 2021-10-28 | 2023-05-04 | Laurus Labs Limited | Methods for preparation of anthranilamide and pyrazole-carboxylate intermediate compounds |
| TW202421613A (zh) * | 2022-10-19 | 2024-06-01 | 美商富曼西公司 | 合成２－胺基－５－氯－ｎ，３－二甲基苯甲醯胺之高效新方法 |
| CN115594608A (zh) * | 2022-10-20 | 2023-01-13 | 九江善水科技股份有限公司（Cn） | 一种氯虫苯甲酰胺中间体的制备方法 |
| CN116730859B (zh) * | 2023-06-01 | 2025-06-13 | 青岛科技大学 | 一种2-氨基-5-氯-n,3-二甲基苯甲酰胺的制备方法 |
| CN116987002A (zh) * | 2023-06-20 | 2023-11-03 | 湖北可赛化工有限公司 | 一种2-氨基-5-氯-n,3-二甲基苯甲酰胺的制备方法 |
| TW202542105A (zh) | 2023-12-19 | 2025-11-01 | 印度商皮埃企業有限公司 | 經取代的鄰胺基苯甲醯胺化合物、其中間產物及其鹽的合成方法 |
| WO2025134140A1 (en) * | 2023-12-19 | 2025-06-26 | Pi Industries Ltd. | A method for the synthesis of substituted anthranilic amide compounds, intermediates and salts thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1421255A (fr) * | 1962-09-18 | 1965-12-17 | Parke Davis & Co | Nouveaux anhydrides d'acides n-arylisatoïques et procédés pour leur préparation |
| DE2262830A1 (de) * | 1972-12-22 | 1974-06-27 | Bayer Ag | Verfahren zur herstellung von oximinoacet-o-toluidid |
| US4569942A (en) * | 1984-05-04 | 1986-02-11 | Pfizer Inc. | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents |
| US6472349B1 (en) | 1999-03-31 | 2002-10-29 | Basf Aktiengesellschaft | Pyridine-2,3-dicarboxylic acid diamides |
| CA2540289A1 (en) * | 2003-10-02 | 2005-04-14 | Cephalon, Inc. | Substituted indole derivatives |
| JP4989976B2 (ja) * | 2004-02-13 | 2012-08-01 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | 翻訳開始阻害剤としての３−３−二置換オキシインドール |
| TWI363756B (en) * | 2004-12-07 | 2012-05-11 | Du Pont | Method for preparing n-phenylpyrazole-1-carboxamides |
| ZA200810231B (en) * | 2006-07-19 | 2010-07-28 | Du Pont | Process for making 3-substituted 2-amino-5-halobenzamides |
| US20110065671A1 (en) * | 2008-05-19 | 2011-03-17 | Harris Joel M | Bicyclic heterocycle derivatives and use thereof as gpr119 modulators |
| CN101786980B (zh) * | 2010-03-31 | 2012-12-05 | 滨海康杰化学有限公司 | 靛红衍生物的合成方法 |
| CN102311424A (zh) * | 2010-07-05 | 2012-01-11 | 温州大学 | 一种氯虫苯甲酰胺关键中间体的合成方法 |
| US8440662B2 (en) * | 2010-10-31 | 2013-05-14 | Endo Pharmaceuticals, Inc. | Substituted quinazoline and pyrido-pyrimidine derivatives |
| CN103058993B (zh) * | 2013-01-08 | 2014-06-04 | 河南师范大学 | 一种氯虫苯甲酰胺的制备方法 |
| EP2984088B1 (en) | 2013-04-12 | 2019-03-20 | Asana BioSciences, LLC | Quinazolines and azaquinazolines as dual inhibitors of ras/raf/mek/erk and pi3k/akt/pten/mtor pathways |
| BR112018007021B1 (pt) * | 2015-10-06 | 2024-01-09 | Proteostasis Therapeutics, Inc | Composto, composição compreendendo os ditos compostos e uso dos mesmos para tratar fibrose cística |
| CN105732462B (zh) * | 2016-02-03 | 2019-01-04 | 常州工程职业技术学院 | 一种合成7-卤代吲哚的方法 |
| BR112022008061A2 (pt) * | 2019-11-01 | 2022-07-12 | Fmc Corp | Processo eficaz para síntese de 2-amino-5-cloro-n,3-dimetilbenzamida |
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2020
- 2020-10-28 BR BR112022008061A patent/BR112022008061A2/pt unknown
- 2020-10-28 JP JP2022500859A patent/JP7730309B2/ja active Active
- 2020-10-28 CN CN202080048608.5A patent/CN114080388A/zh active Pending
- 2020-10-28 IL IL313390A patent/IL313390A/en unknown
- 2020-10-28 PL PL20811479.3T patent/PL3976583T3/pl unknown
- 2020-10-28 MX MX2022005229A patent/MX2022005229A/es unknown
- 2020-10-28 CN CN202210355074.1A patent/CN114621130B/zh active Active
- 2020-10-28 TW TW112144552A patent/TWI881549B/zh active
- 2020-10-28 KR KR1020227017904A patent/KR20220091537A/ko active Pending
- 2020-10-28 IL IL294707A patent/IL294707B2/en unknown
- 2020-10-28 CN CN202211336205.8A patent/CN115536540B/zh active Active
- 2020-10-28 AU AU2020372895A patent/AU2020372895A1/en active Pending
- 2020-10-28 EP EP20811479.3A patent/EP3976583B1/en active Active
- 2020-10-28 HU HUE20811479A patent/HUE067805T2/hu unknown
- 2020-10-28 WO PCT/US2020/057726 patent/WO2021086957A1/en not_active Ceased
- 2020-10-28 MA MA056056A patent/MA56056A/fr unknown
- 2020-10-28 EP EP22190852.8A patent/EP4119542A1/en active Pending
- 2020-10-28 TW TW109137402A patent/TW202126616A/zh unknown
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2022
- 2022-04-13 IL IL292210A patent/IL292210B2/en unknown
- 2022-04-15 US US17/721,781 patent/US11542241B2/en active Active
- 2022-04-28 JP JP2022073949A patent/JP2023002456A/ja active Pending
- 2022-04-29 MX MX2026001742A patent/MX2026001742A/es unknown
- 2022-04-29 ZA ZA2022/04803A patent/ZA202204803B/en unknown
- 2022-11-29 US US18/070,827 patent/US12304893B2/en active Active
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2024
- 2024-04-29 ZA ZA2024/03308A patent/ZA202403308B/en unknown
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2025
- 2025-01-09 JP JP2025003220A patent/JP2025061138A/ja active Pending
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