MX2022004962A - Fármaco para el tratamiento del cáncer, combinación de fármacos, composición de fármacos, célula de respuesta inmune, vehículo de administración de ácidos nucleicos y producto. - Google Patents

Fármaco para el tratamiento del cáncer, combinación de fármacos, composición de fármacos, célula de respuesta inmune, vehículo de administración de ácidos nucleicos y producto.

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Publication number
MX2022004962A
MX2022004962A MX2022004962A MX2022004962A MX2022004962A MX 2022004962 A MX2022004962 A MX 2022004962A MX 2022004962 A MX2022004962 A MX 2022004962A MX 2022004962 A MX2022004962 A MX 2022004962A MX 2022004962 A MX2022004962 A MX 2022004962A
Authority
MX
Mexico
Prior art keywords
drug
nucleic acid
responsive cell
immune responsive
combination
Prior art date
Application number
MX2022004962A
Other languages
English (en)
Inventor
Koji Tamada
Yukimi Sakoda
Keishi Adachi
Original Assignee
Noile Immune Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noile Immune Biotech Inc filed Critical Noile Immune Biotech Inc
Publication of MX2022004962A publication Critical patent/MX2022004962A/es

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Abstract

Una combinación ejemplar de fármacos que incluye (a1) una célula inmunorreactiva que libera interleucina-7, CCL19 y una molécula de superficie celular que reconoce específicamente un antígeno canceroso o (a2) uno o más tipos de células, uno o más tipos de vehículos de administración de pacido nucleico, o una combinación de los mismos, que incluyen cooperativamente un ácido nucleico que codifica interleucina-7 y un ácido nucleico que codifica CCL19; y (b) un inhibidor de la inmunosupresión donde el fármaco se emplea para el tratamiento de un cáncer en un sujeto. Una célula inmunorreactiva ejemplar secreta interleucina-7, CCL19, un polipéptido inhibidor de la inmunosupresión y una molécula de superficie celular que reconoce específicamente un antígeno del cáncer.
MX2022004962A 2019-10-28 2020-10-28 Fármaco para el tratamiento del cáncer, combinación de fármacos, composición de fármacos, célula de respuesta inmune, vehículo de administración de ácidos nucleicos y producto. MX2022004962A (es)

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