MX2022003367A - Polipeptidos moduladores de linfocitos t y metodos de uso de estos. - Google Patents
Polipeptidos moduladores de linfocitos t y metodos de uso de estos.Info
- Publication number
- MX2022003367A MX2022003367A MX2022003367A MX2022003367A MX2022003367A MX 2022003367 A MX2022003367 A MX 2022003367A MX 2022003367 A MX2022003367 A MX 2022003367A MX 2022003367 A MX2022003367 A MX 2022003367A MX 2022003367 A MX2022003367 A MX 2022003367A
- Authority
- MX
- Mexico
- Prior art keywords
- polypeptides
- lymphocyte
- methods
- cell
- modulating
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 6
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 3
- 229940125750 lymphocyte modulator Drugs 0.000 title 1
- 101000584612 Homo sapiens GTPase KRas Proteins 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 108091008874 T cell receptors Proteins 0.000 abstract 1
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 abstract 1
- 102000015736 beta 2-Microglobulin Human genes 0.000 abstract 1
- 108010081355 beta 2-Microglobulin Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962903441P | 2019-09-20 | 2019-09-20 | |
| US202062990693P | 2020-03-17 | 2020-03-17 | |
| US202063048561P | 2020-07-06 | 2020-07-06 | |
| PCT/US2020/051255 WO2021055594A1 (en) | 2019-09-20 | 2020-09-17 | T-cell modulatory polypeptides and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022003367A true MX2022003367A (es) | 2022-04-11 |
Family
ID=74884186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022003367A MX2022003367A (es) | 2019-09-20 | 2020-09-17 | Polipeptidos moduladores de linfocitos t y metodos de uso de estos. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20220143063A1 (enExample) |
| EP (1) | EP4030897A4 (enExample) |
| JP (1) | JP7756072B2 (enExample) |
| KR (1) | KR20220066075A (enExample) |
| CN (1) | CN114423284A (enExample) |
| AU (1) | AU2020348373A1 (enExample) |
| CA (1) | CA3146591A1 (enExample) |
| IL (1) | IL290635A (enExample) |
| MX (1) | MX2022003367A (enExample) |
| TW (1) | TW202126683A (enExample) |
| WO (1) | WO2021055594A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2973548T3 (es) | 2016-12-22 | 2024-06-20 | Cue Biopharma Inc | Polipéptidos multiméricos moduladores de linfocitos T y métodos para su uso |
| US20200010528A1 (en) | 2017-03-15 | 2020-01-09 | Cue Biopharma, Inc. | Methods for modulating an immune response |
| JP2020534352A (ja) | 2017-09-07 | 2020-11-26 | キュー バイオファーマ，インコーポレーテッド | コンジュゲーション部位を有するｔ細胞調節多量体ポリペプチド及びその使用方法 |
| TWI856047B (zh) * | 2018-12-19 | 2024-09-21 | 美商信號生物製藥公司 | 多聚體ｔ細胞調節多肽及其使用方法 |
| US12453774B2 (en) * | 2019-11-07 | 2025-10-28 | Genoimmune Therapeutics Co., Ltd. | Tumor immunotherapy polypeptide and application thereof |
| WO2021231376A2 (en) | 2020-05-12 | 2021-11-18 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| WO2022056014A1 (en) | 2020-09-09 | 2022-03-17 | Cue Biopharma, Inc. | Mhc class ii t-cell modulatory multimeric polypeptides for treating type 1 diabetes mellitus (t1d) and methods of use thereof |
| CN116710115A (zh) | 2020-11-20 | 2023-09-05 | 思维疗法股份有限公司 | 用于优化的肽疫苗的组合物和方法 |
| US11421015B2 (en) | 2020-12-07 | 2022-08-23 | Think Therapeutics, Inc. | Method of compact peptide vaccines using residue optimization |
| US11058751B1 (en) | 2020-11-20 | 2021-07-13 | Think Therapeutics, Inc. | Compositions for optimized RAS peptide vaccines |
| US12275766B2 (en) * | 2020-12-23 | 2025-04-15 | Janssen Biotech, Inc. | Neoantigen peptide mimics |
| AU2022238389A1 (en) * | 2021-03-19 | 2023-10-05 | Cue Biopharma, Inc. | T-cell modulatory polypeptides and methods of use thereof |
| US11464842B1 (en) | 2021-04-28 | 2022-10-11 | Think Therapeutics, Inc. | Compositions and method for optimized peptide vaccines using residue optimization |
| JP2025511703A (ja) * | 2022-04-07 | 2025-04-16 | キュー バイオファーマ， インコーポレイテッド | 免疫細胞結合ポリペプチド |
| CN115820736B (zh) * | 2022-12-08 | 2024-05-10 | 西南大学 | 家蚕丝胶蛋白Ser4在提高蚕丝性能中的应用及其方法 |
| WO2024264004A2 (en) * | 2023-06-23 | 2024-12-26 | Cue Biopharma, Inc. | T-cell modulatory polypeptides and methods of use thereof |
| WO2024264007A2 (en) * | 2023-06-23 | 2024-12-26 | Cue Biopharma, Inc. | T-cell modulatory polypeptides and methods of use thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015195531A2 (en) * | 2014-06-18 | 2015-12-23 | Albert Einstein College Of Medicine, Inc. | Syntac polypeptides and uses thereof |
| WO2016154246A1 (en) * | 2015-03-23 | 2016-09-29 | The Johns Hopkins University | Hla-restricted epitopes encoded by somatically mutated genes |
| AU2017213117A1 (en) * | 2016-01-27 | 2018-07-19 | CSL Behring Lengnau AG | Recombinant IgG Fc multimers |
| WO2017151818A2 (en) * | 2016-03-02 | 2017-09-08 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| CA3014466A1 (en) * | 2016-03-03 | 2017-09-08 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| WO2017201210A1 (en) * | 2016-05-18 | 2017-11-23 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| ES2973548T3 (es) * | 2016-12-22 | 2024-06-20 | Cue Biopharma Inc | Polipéptidos multiméricos moduladores de linfocitos T y métodos para su uso |
| EP3565829A4 (en) * | 2017-01-09 | 2021-01-27 | Cue Biopharma, Inc. | T-CELL-MODULATING MULTIMERIC POLYPEPTIDES AND METHOD OF USING THEREOF |
| US20200010528A1 (en) * | 2017-03-15 | 2020-01-09 | Cue Biopharma, Inc. | Methods for modulating an immune response |
| JP2020534352A (ja) * | 2017-09-07 | 2020-11-26 | キュー バイオファーマ，インコーポレーテッド | コンジュゲーション部位を有するｔ細胞調節多量体ポリペプチド及びその使用方法 |
| CN111886241A (zh) * | 2018-01-09 | 2020-11-03 | 库尔生物制药有限公司 | 多聚体t细胞调节多肽及其使用方法 |
| JP7153287B2 (ja) * | 2020-05-12 | 2022-10-14 | 住友ファーマ株式会社 | 癌を処置するための医薬組成物 |
-
2020
- 2020-09-17 CA CA3146591A patent/CA3146591A1/en active Pending
- 2020-09-17 CN CN202080065140.0A patent/CN114423284A/zh active Pending
- 2020-09-17 WO PCT/US2020/051255 patent/WO2021055594A1/en not_active Ceased
- 2020-09-17 EP EP20865317.0A patent/EP4030897A4/en active Pending
- 2020-09-17 AU AU2020348373A patent/AU2020348373A1/en not_active Abandoned
- 2020-09-17 MX MX2022003367A patent/MX2022003367A/es unknown
- 2020-09-17 JP JP2022506595A patent/JP7756072B2/ja active Active
- 2020-09-17 KR KR1020227009918A patent/KR20220066075A/ko not_active Withdrawn
- 2020-09-18 TW TW109132369A patent/TW202126683A/zh unknown
-
2022
- 2022-01-25 US US17/584,133 patent/US20220143063A1/en not_active Abandoned
- 2022-02-15 IL IL290635A patent/IL290635A/en unknown
-
2024
- 2024-10-01 US US18/903,947 patent/US20250120996A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021055594A1 (en) | 2021-03-25 |
| EP4030897A1 (en) | 2022-07-27 |
| TW202126683A (zh) | 2021-07-16 |
| KR20220066075A (ko) | 2022-05-23 |
| US20250120996A1 (en) | 2025-04-17 |
| EP4030897A4 (en) | 2023-10-18 |
| US20220143063A1 (en) | 2022-05-12 |
| JP2022548472A (ja) | 2022-11-21 |
| JP7756072B2 (ja) | 2025-10-17 |
| CA3146591A1 (en) | 2021-03-25 |
| IL290635A (en) | 2022-04-01 |
| AU2020348373A1 (en) | 2022-02-24 |
| CN114423284A (zh) | 2022-04-29 |
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