MX2021011733A - Metodos para la extraccion y purificacion continua de un extracto unico de flavan-3-ol de racimos de uvas enteras inmaduras y composiciones del mismo. - Google Patents

Metodos para la extraccion y purificacion continua de un extracto unico de flavan-3-ol de racimos de uvas enteras inmaduras y composiciones del mismo.

Info

Publication number
MX2021011733A
MX2021011733A MX2021011733A MX2021011733A MX2021011733A MX 2021011733 A MX2021011733 A MX 2021011733A MX 2021011733 A MX2021011733 A MX 2021011733A MX 2021011733 A MX2021011733 A MX 2021011733A MX 2021011733 A MX2021011733 A MX 2021011733A
Authority
MX
Mexico
Prior art keywords
flavan
final product
continuous extraction
purification
extract
Prior art date
Application number
MX2021011733A
Other languages
English (en)
Inventor
James A Kennedy
Original Assignee
Gallo Winery E & J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gallo Winery E & J filed Critical Gallo Winery E & J
Publication of MX2021011733A publication Critical patent/MX2021011733A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/42Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424Elution mode
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00Food ingredients
    • A23V2250/30Other Organic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2300/00Processes
    • A23V2300/14Extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/37Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/55Liquid-liquid separation; Phase separation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Physiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pyrane Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Preparation Of Fruits And Vegetables (AREA)

Abstract

La presente descripción proporciona un proceso novedoso para la extracción, purificación y producción continua de un extracto de flavan-3-ol de racimos de uvas enteras cosechadas tempranamente. El producto final de este proceso es particularmente rico en flavan-3-oles monoméricos y oligoméricos y con una conversión inusualmente alta del producto final en subunidades de flavan-3-ol bajo condiciones de catálisis ácida. Los oligómeros y polímeros en el producto final se refieren frecuentemente como proantocianidinas en el campo de la química de polifenoles. La descripción proporciona un proceso novedoso para la producción del producto final mediante un proceso de extracción continua y con un producto final que tiene una composición única.
MX2021011733A 2019-03-25 2020-03-16 Metodos para la extraccion y purificacion continua de un extracto unico de flavan-3-ol de racimos de uvas enteras inmaduras y composiciones del mismo. MX2021011733A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962823390P 2019-03-25 2019-03-25
PCT/US2020/022958 WO2020197828A1 (en) 2019-03-25 2020-03-16 Methods for continuous extraction and purification of a unique flavan-3-ol extract from immature whole grape clusters and compositions thereof

Publications (1)

Publication Number Publication Date
MX2021011733A true MX2021011733A (es) 2021-10-22

Family

ID=72609052

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021011733A MX2021011733A (es) 2019-03-25 2020-03-16 Metodos para la extraccion y purificacion continua de un extracto unico de flavan-3-ol de racimos de uvas enteras inmaduras y composiciones del mismo.

Country Status (12)

Country Link
US (1) US20220160810A1 (es)
EP (1) EP3946286A4 (es)
JP (1) JP2022526959A (es)
KR (1) KR20210142697A (es)
CN (1) CN113874003A (es)
AU (1) AU2020244715A1 (es)
BR (1) BR112021019150A2 (es)
CA (1) CA3134699A1 (es)
CL (1) CL2021002468A1 (es)
IL (1) IL286597A (es)
MX (1) MX2021011733A (es)
WO (1) WO2020197828A1 (es)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544581B1 (en) * 1999-06-22 2003-04-08 Canandaigua Wine Company, Inc. Process for extraction, purification and enrichment of polyphenolic substances from whole grapes, grape seeds and grape pomace
BR0107486A (pt) * 2000-01-11 2002-10-08 Biorex Health Ltd Método de extração de uma aglicona flavonóide a partir de material inicial contendo uma glicosida flavonóide e/ou conjugado dela proveniente
US20020001651A1 (en) * 2000-01-24 2002-01-03 Norris Leslie Marie Method of altering and improving taste characteristics of edible consumables with monomeric or oligomeric polyphenolic compounds
ITMI20051485A1 (it) * 2005-07-29 2007-01-30 Indena Spa Estratto da semi d'uva ottenibile per frazionamento su resina
JP5424641B2 (ja) * 2005-09-28 2014-02-26 コンステレーション・ブランズ・インコーポレーテッド ブドウ抽出物、そのダイエタリーサプリメント、およびその方法
AU2012244182B2 (en) * 2005-09-28 2013-09-19 E. & J. Gallo Winery Grape extract, dietary supplement thereof, and processes therefor
ES2337868B1 (es) * 2008-10-16 2011-03-10 Universitat Rovira I Virgili Composicion para el tratamiento del sindrome metabolico.
US20120135109A1 (en) * 2010-11-30 2012-05-31 Tropicana Products, Inc. Fiber obtained from fruit or vegetable byproducts
US20150259315A1 (en) * 2014-03-14 2015-09-17 Constellation Brands, Inc. Grape extract, dietary supplement thereof, and processes therefor
CN106455637A (zh) * 2014-05-30 2017-02-22 嘉康利公司 霞多丽葡萄籽提取物

Also Published As

Publication number Publication date
JP2022526959A (ja) 2022-05-27
KR20210142697A (ko) 2021-11-25
BR112021019150A2 (pt) 2021-12-07
EP3946286A4 (en) 2022-12-21
US20220160810A1 (en) 2022-05-26
CL2021002468A1 (es) 2022-06-10
CN113874003A (zh) 2021-12-31
EP3946286A1 (en) 2022-02-09
CA3134699A1 (en) 2020-10-01
WO2020197828A1 (en) 2020-10-01
IL286597A (en) 2021-12-01
AU2020244715A1 (en) 2021-10-14

Similar Documents

Publication Publication Date Title
IN2015DN03728A (es)
MX2013013819A (es) Procedimiento para la extraccion de pectina.
MY185547A (en) Dry fractionation method for a transesterified oil and fat composition
PH12017502056A1 (en) A biostimulant formulation for improving plant growth and uses thereof
MX2012012522A (es) Procedimiento para inocular levadura en zumo de frutas.
NO20091275L (no) Polyfenolrikt ekstrakt fra plantemateriale
CN105483009A (zh) 一种生产破壁雨生红球藻粉的方法
WO2010117843A3 (en) Termite enzymes and uses thereof for in vitro conversion of lignin-containing materials to fermentable products
MX2018002830A (es) Proceso para la extraccion de silice.
MX2021011733A (es) Metodos para la extraccion y purificacion continua de un extracto unico de flavan-3-ol de racimos de uvas enteras inmaduras y composiciones del mismo.
EA201790710A1 (ru) Способ получения глатирамера ацетата
MY180704A (en) Method for improved reactive monomer production with membrane filtration
EA201590366A1 (ru) Способ получения циклических сложных диэфиров, в частности дилактида
MX2018010128A (es) Toxina nueva y metodo de preparacion de un intermediario de la misma.
RU2008116537A (ru) Способ переработки коры деревьев хвойных пород
EA201692327A1 (ru) Пролин-специфическая эндопротеаза
RU2529836C1 (ru) Способ получения пищевого концентрата полифенолов винограда
PH12015501949A1 (en) Method for preparing a muscadine pomace extract
MX2022015503A (es) Procedimiento de extraccion de acido hialuronico de un hongo, acido hialuronico de origen vegetal y uso del mismo.
WO2012089843A3 (en) Extraction of scenedesmus cell components
MY197373A (en) Methods for optimizing gas utilization
RU145616U1 (ru) Способ получения пищевого концентрата полифенолов
EA201300476A1 (ru) Способ производства игристого вина
CN110498826B (zh) 一种欧洲越橘花色甙的制备方法及其副产物的处理方法
EA201900218A1 (ru) Способ подготовки форменных элементов крови к использованию на пищевые цели