MX2021010913A - Cubierta de capsula que comprende un polimero de nucleo-cubierta y una celulosa. - Google Patents

Cubierta de capsula que comprende un polimero de nucleo-cubierta y una celulosa.

Info

Publication number
MX2021010913A
MX2021010913A MX2021010913A MX2021010913A MX2021010913A MX 2021010913 A MX2021010913 A MX 2021010913A MX 2021010913 A MX2021010913 A MX 2021010913A MX 2021010913 A MX2021010913 A MX 2021010913A MX 2021010913 A MX2021010913 A MX 2021010913A
Authority
MX
Mexico
Prior art keywords
shell
weight
core
cellulose
polymer
Prior art date
Application number
MX2021010913A
Other languages
English (en)
Inventor
Manfred Assmus
Kathrin Nollenberger
Bettina HÖLZER
Original Assignee
Evonik Operations Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Operations Gmbh filed Critical Evonik Operations Gmbh
Publication of MX2021010913A publication Critical patent/MX2021010913A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/077Manufacturing capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C41/00Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
    • B29C41/02Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • B29C41/14Dipping a core
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2033/00Use of polymers of unsaturated acids or derivatives thereof as moulding material
    • B29K2033/04Polymers of esters
    • B29K2033/12Polymers of methacrylic acid esters, e.g. PMMA, i.e. polymethylmethacrylate
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0058Liquid or visquous
    • B29K2105/0064Latex, emulsion or dispersion
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0094Condition, form or state of moulded material or of the material to be shaped having particular viscosity

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Graft Or Block Polymers (AREA)

Abstract

La invención se refiere a una cubierta de cápsula que comprende 40 a 99% en peso de un polímero de núcleo-cubierta, que comprende 50 a 90% en peso de un núcleo, que comprende unidades polimerizada de 65 a 75% en peso de acrilato de etilo y 25 a 35% en peso metacrilato de metilo, y 10 a 50% en peso de una cubierta, que comprende unidades polimerizadas de 45 a 55% en peso de acrilato de etilo y 45 a 55% en peso de ácido metacrílico, y 1 a 60% en peso de una celulosa.
MX2021010913A 2019-03-14 2020-03-05 Cubierta de capsula que comprende un polimero de nucleo-cubierta y una celulosa. MX2021010913A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19162778 2019-03-14
PCT/EP2020/055848 WO2020182611A1 (en) 2019-03-14 2020-03-05 Capsule shell comprising a core-shell polymer and a cellulose

Publications (1)

Publication Number Publication Date
MX2021010913A true MX2021010913A (es) 2021-10-01

Family

ID=65812177

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021010913A MX2021010913A (es) 2019-03-14 2020-03-05 Cubierta de capsula que comprende un polimero de nucleo-cubierta y una celulosa.

Country Status (10)

Country Link
US (1) US11904056B2 (es)
EP (1) EP3937909A1 (es)
JP (1) JP2022525180A (es)
KR (1) KR20210139263A (es)
CN (1) CN113677331A (es)
BR (1) BR112021017885A2 (es)
CA (1) CA3130184A1 (es)
IL (1) IL286322A (es)
MX (1) MX2021010913A (es)
WO (1) WO2020182611A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021503463A (ja) 2017-11-17 2021-02-12 エボニック オペレーションズ ゲーエムベーハー コーティングされた硬カプセルを製造する方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138013A (en) 1976-08-27 1979-02-06 Parke, Davis & Company Enteric capsules
JP2959423B2 (ja) * 1994-12-01 1999-10-06 シオノギクオリカプス株式会社 カプセル用皮膜組成物
GB0706178D0 (en) * 2007-03-29 2007-05-09 Univ Aston Enteric pharmaceutical capsules
US20090041666A1 (en) * 2007-05-21 2009-02-12 Goldstein Lee E Ophthalmic formulations of Amyloid-beta contrast agent and methods of use thereof
US9107451B2 (en) * 2009-07-29 2015-08-18 Evonik Röhm Gmbh Coating composition for the dip coating of capsule halves
DE102009028076A1 (de) 2009-07-29 2011-02-03 Evonik Röhm Gmbh Beschichtungsmittel zum Tauchbeschichten von Kapselhälften
ES2804779T3 (es) * 2009-09-24 2021-02-09 Capsugel Belgium Nv Cápsulas resistentes a los ácidos
JP5890428B2 (ja) 2010-10-26 2016-03-22 キャプシュゲル・ベルジウム・エヌ・ヴィ バルク腸溶カプセルシェル
AU2011370762A1 (en) * 2011-06-17 2013-11-14 Evonik Rohm Gmbh Coating composition suitable for pharmaceutical or nutraceutical dosage forms
EP3524271A1 (en) 2012-05-02 2019-08-14 Capsugel Belgium NV Aqueous dispersions of hydroxypropyl methylcellulose acetate succinate (hpmcas)
CN104661655A (zh) 2012-07-23 2015-05-27 陶氏环球技术有限责任公司 用于硬质胶囊外壳的膜组合物
CA2950203C (en) * 2014-06-20 2019-09-03 Banner Life Sciences Llc Enteric soft capsule compositions
CN110891552B (zh) * 2017-07-11 2023-06-02 快力胶囊股份有限公司 肠溶性硬质胶囊
JP2021503463A (ja) 2017-11-17 2021-02-12 エボニック オペレーションズ ゲーエムベーハー コーティングされた硬カプセルを製造する方法
JP2022533610A (ja) * 2019-05-15 2022-07-25 エボニック オペレーションズ ゲーエムベーハー カプセル充填機を用いて、(メタ)アクリレートコポリマー系のコーティングを有する、充填されたハードシェルカプセルを製造する方法

Also Published As

Publication number Publication date
EP3937909A1 (en) 2022-01-19
CA3130184A1 (en) 2020-09-17
IL286322A (en) 2021-10-31
JP2022525180A (ja) 2022-05-11
CN113677331A (zh) 2021-11-19
US11904056B2 (en) 2024-02-20
BR112021017885A2 (pt) 2021-12-07
WO2020182611A1 (en) 2020-09-17
US20220142929A1 (en) 2022-05-12
KR20210139263A (ko) 2021-11-22

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