MX2021000326A - Desoxirribosa-fosfato aldolasas modificadas geneticamente. - Google Patents

Desoxirribosa-fosfato aldolasas modificadas geneticamente.

Info

Publication number
MX2021000326A
MX2021000326A MX2021000326A MX2021000326A MX2021000326A MX 2021000326 A MX2021000326 A MX 2021000326A MX 2021000326 A MX2021000326 A MX 2021000326A MX 2021000326 A MX2021000326 A MX 2021000326A MX 2021000326 A MX2021000326 A MX 2021000326A
Authority
MX
Mexico
Prior art keywords
engineered deoxyribose
phosphate aldolases
phosphate
deoxyribose
aldolases
Prior art date
Application number
MX2021000326A
Other languages
English (en)
Inventor
Hao Yang
Anna Fryszkowska
Oscar Alvizo
Jonathan Vroom
James Nicholas Riggins
Da Duan
Jovana Nazor
Santhosh Sivaramakrishnan
Mark Huffman
Agustina Rodriguez-Granillo
Deeptak Verma
Joshua Kolev
Harvinder Chagger Maniar
Iman Farasat
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of MX2021000326A publication Critical patent/MX2021000326A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/02—Aldehyde-lyases (4.1.2)
    • C12Y401/02004—Deoxyribose-phosphate aldolase (4.1.2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención proporciona polipéptidos de desoxirribosa-fosfato aldolasa modificada genéticamente útiles en condiciones de procedimientos industriales para la producción de compuestos químicos finos y farmacéuticos.
MX2021000326A 2018-07-09 2019-07-02 Desoxirribosa-fosfato aldolasas modificadas geneticamente. MX2021000326A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862695520P 2018-07-09 2018-07-09
US201962822273P 2019-03-22 2019-03-22
PCT/US2019/040369 WO2020014048A1 (en) 2018-07-09 2019-07-02 Engineered deoxyribose-phosphate aldolases

Publications (1)

Publication Number Publication Date
MX2021000326A true MX2021000326A (es) 2021-03-25

Family

ID=69101203

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021000326A MX2021000326A (es) 2018-07-09 2019-07-02 Desoxirribosa-fosfato aldolasas modificadas geneticamente.

Country Status (11)

Country Link
US (3) US11274286B2 (es)
EP (1) EP3821015A4 (es)
JP (1) JP7462969B2 (es)
KR (1) KR20210032417A (es)
CN (1) CN112673105A (es)
AU (1) AU2019300836A1 (es)
CA (1) CA3103721A1 (es)
IL (1) IL279882A (es)
MX (1) MX2021000326A (es)
SG (1) SG11202012107RA (es)
WO (1) WO2020014048A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
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BR112021000202B1 (pt) * 2018-07-09 2023-03-28 Merck Sharp & Dohme Llc Métodos para síntese enzimática de nucleosídeo 4'-etinila 2-desóxi e compostos
US11274286B2 (en) 2018-07-09 2022-03-15 Codexis, Inc. Engineered deoxyribose-phosphate aldolases
BR112021014576A2 (pt) 2019-01-25 2021-10-05 Brown University Composições e métodos para tratamento, prevenção ou reversão de inflamação e distúrbios associados à idade
KR20240008455A (ko) * 2022-07-11 2024-01-19 대상 주식회사 L-글루탐산을 생산하는 코리네박테리움 속 변이 미생물 및 이를 이용한 l-글루탐산의 생산 방법

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Also Published As

Publication number Publication date
EP3821015A1 (en) 2021-05-19
EP3821015A4 (en) 2022-07-13
IL279882A (en) 2021-03-01
JP2021530980A (ja) 2021-11-18
CA3103721A1 (en) 2020-01-16
WO2020014048A1 (en) 2020-01-16
US20240076647A1 (en) 2024-03-07
KR20210032417A (ko) 2021-03-24
US11274286B2 (en) 2022-03-15
US11845968B2 (en) 2023-12-19
CN112673105A (zh) 2021-04-16
US20200010868A1 (en) 2020-01-09
SG11202012107RA (en) 2021-01-28
AU2019300836A1 (en) 2021-01-07
US20220162580A1 (en) 2022-05-26
JP7462969B2 (ja) 2024-04-08

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