MX2020011537A - Esteroides neuroactivos, composiciones y uso de los mismos. - Google Patents

Esteroides neuroactivos, composiciones y uso de los mismos.

Info

Publication number
MX2020011537A
MX2020011537A MX2020011537A MX2020011537A MX2020011537A MX 2020011537 A MX2020011537 A MX 2020011537A MX 2020011537 A MX2020011537 A MX 2020011537A MX 2020011537 A MX2020011537 A MX 2020011537A MX 2020011537 A MX2020011537 A MX 2020011537A
Authority
MX
Mexico
Prior art keywords
depression
tremor
compositions
neuroactive steroids
anxiety disorder
Prior art date
Application number
MX2020011537A
Other languages
English (en)
Inventor
Stephen Jay Kanes
Helen Colquhoun
Original Assignee
Sage Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sage Therapeutics Inc filed Critical Sage Therapeutics Inc
Publication of MX2020011537A publication Critical patent/MX2020011537A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Se describen en la presente métodos tratar temblor, por ejemplo, temblor esencial; depresión, por ejemplo, posparto depresión; y trastorno de ansiedad, el método comprende administrar a un sujeto humano que padece de temblor, por ejemplo, temblor esencial; depresión, por ejemplo, posparto depresión, un trastorno de ansiedad con un esteroide neuroactivo o una composición que comprende un esteroide neuroactivo (por ejemplo, pregnanolona, alopregnanolona, alfadalona, ganaxolona, o alfaxolona).
MX2020011537A 2014-09-08 2017-03-08 Esteroides neuroactivos, composiciones y uso de los mismos. MX2020011537A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462047599P 2014-09-08 2014-09-08
US201562170596P 2015-06-03 2015-06-03
US201562213015P 2015-09-01 2015-09-01

Publications (1)

Publication Number Publication Date
MX2020011537A true MX2020011537A (es) 2020-11-24

Family

ID=55459478

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017003037A MX2017003037A (es) 2014-09-08 2015-09-08 Esteroides neuroactivos, composiciones y usos de los mismos.
MX2020011537A MX2020011537A (es) 2014-09-08 2017-03-08 Esteroides neuroactivos, composiciones y uso de los mismos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2017003037A MX2017003037A (es) 2014-09-08 2015-09-08 Esteroides neuroactivos, composiciones y usos de los mismos.

Country Status (18)

Country Link
US (2) US20170348327A1 (es)
EP (1) EP3191101A4 (es)
JP (3) JP6837430B2 (es)
KR (2) KR102491549B1 (es)
CN (2) CN117679426A (es)
AU (3) AU2015315333A1 (es)
BR (1) BR112017004535A2 (es)
CA (1) CA2960611A1 (es)
CO (1) CO2017003396A2 (es)
IL (2) IL285703B2 (es)
JO (2) JOP20200195A1 (es)
MX (2) MX2017003037A (es)
PE (2) PE20170904A1 (es)
PH (1) PH12017500427A1 (es)
RU (2) RU2731000C2 (es)
SG (2) SG11201701815SA (es)
TW (3) TW202329978A (es)
WO (1) WO2016040322A1 (es)

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WO2018147791A1 (en) * 2017-02-10 2018-08-16 Asarina Pharma Ab 3-beta-hydroxy-5-alpha-pregnan-20-one for use in treatment of essential tremor
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AU2019377074A1 (en) * 2018-11-05 2021-05-13 Ovid Therapeutics Inc. Use of gaboxadol, ganaxolone and allopregnanolone to treat movement disorders
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WO2020118142A1 (en) 2018-12-07 2020-06-11 Marinus Pharmaceuticals, Inc. Ganaxolone for use in prophylaxis and treatment of pospartum depression
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WO2024054875A2 (en) * 2022-09-07 2024-03-14 Oxeia Biopharmaceuticals, Inc. Treatment of mild traumatic brain injury

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Also Published As

Publication number Publication date
JO3667B1 (ar) 2020-08-27
JP2022113879A (ja) 2022-08-04
KR20230015518A (ko) 2023-01-31
PE20170904A1 (es) 2017-07-12
TWI784261B (zh) 2022-11-21
JP2017526703A (ja) 2017-09-14
CN107106574A (zh) 2017-08-29
KR20170048567A (ko) 2017-05-08
AU2021202433C1 (en) 2024-01-25
PH12017500427A1 (en) 2017-07-31
RU2020127610A (ru) 2021-09-30
WO2016040322A1 (en) 2016-03-17
SG11201701815SA (en) 2017-04-27
TW202329978A (zh) 2023-08-01
IL285703B1 (en) 2023-11-01
KR102491549B1 (ko) 2023-01-20
TW202106306A (zh) 2021-02-16
PE20221050A1 (es) 2022-06-30
EP3191101A4 (en) 2018-04-11
IL285703B2 (en) 2024-03-01
JP2020059760A (ja) 2020-04-16
JOP20200195A1 (ar) 2017-06-16
AU2023248120A1 (en) 2023-11-02
RU2731000C2 (ru) 2020-08-26
RU2017111816A (ru) 2018-10-10
AU2021202433B2 (en) 2023-07-13
IL285703A (en) 2021-09-30
TWI688389B (zh) 2020-03-21
EP3191101A1 (en) 2017-07-19
MX2017003037A (es) 2017-06-14
BR112017004535A2 (pt) 2018-07-03
CA2960611A1 (en) 2016-03-17
IL250942A0 (en) 2017-04-30
AU2015315333A1 (en) 2017-03-23
CO2017003396A2 (es) 2017-08-31
CN117679426A (zh) 2024-03-12
TW201625266A (zh) 2016-07-16
IL250942B (en) 2021-09-30
AU2021202433A1 (en) 2021-05-13
SG10202107866YA (en) 2021-08-30
US20200253985A1 (en) 2020-08-13
RU2017111816A3 (es) 2019-05-08
JP6837430B2 (ja) 2021-03-03
US20170348327A1 (en) 2017-12-07

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