MX2020011200A - Compuestos heteroaromaticos que tienen actividad contra vrs. - Google Patents

Compuestos heteroaromaticos que tienen actividad contra vrs.

Info

Publication number
MX2020011200A
MX2020011200A MX2020011200A MX2020011200A MX2020011200A MX 2020011200 A MX2020011200 A MX 2020011200A MX 2020011200 A MX2020011200 A MX 2020011200A MX 2020011200 A MX2020011200 A MX 2020011200A MX 2020011200 A MX2020011200 A MX 2020011200A
Authority
MX
Mexico
Prior art keywords
activity against
compounds
heteroaromatic compounds
against rsv
respiratory syncytial
Prior art date
Application number
MX2020011200A
Other languages
English (en)
Inventor
Antoine Benjamin Michaut
David Francis Alain Lançois
Dirk André Emmy Roymans
Pierre Jean - Marie Bernard Raboisson
Peter Rigaux
Jérome Émile Georges Guillemont
Sabrina Dany France Quatrevaux
Sovy Chao
Original Assignee
Janssen Sciences Ireland Unlimited Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Unlimited Co filed Critical Janssen Sciences Ireland Unlimited Co
Publication of MX2020011200A publication Critical patent/MX2020011200A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)

Abstract

La invención se refiere a compuestos de fórmula (I) que tienen actividad antiviral, en particular, que tienen una actividad inhibidora sobre la replicación del virus respiratorio sincicial (VRS); la invención se refiere además a composiciones farmacéuticas que comprenden estos compuestos y los compuestos para su uso en el tratamiento de la infección por el virus respiratorio sincicial. (ver Fórmula).
MX2020011200A 2018-04-23 2019-04-19 Compuestos heteroaromaticos que tienen actividad contra vrs. MX2020011200A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18168671 2018-04-23
PCT/EP2019/060216 WO2019206828A1 (en) 2018-04-23 2019-04-19 Heteroaromatic compounds having activity against rsv

Publications (1)

Publication Number Publication Date
MX2020011200A true MX2020011200A (es) 2020-11-13

Family

ID=62046706

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020011200A MX2020011200A (es) 2018-04-23 2019-04-19 Compuestos heteroaromaticos que tienen actividad contra vrs.

Country Status (13)

Country Link
US (1) US11708369B2 (es)
EP (1) EP3784667B1 (es)
JP (1) JP2021522222A (es)
KR (1) KR20210005569A (es)
CN (1) CN112004815A (es)
AU (1) AU2019260109B2 (es)
CA (1) CA3095277A1 (es)
EA (1) EA202092439A1 (es)
ES (1) ES2957316T3 (es)
MA (1) MA52348A (es)
MX (1) MX2020011200A (es)
SG (1) SG11202010323QA (es)
WO (1) WO2019206828A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA202091835A1 (ru) 2018-01-31 2020-10-20 Янссен Сайенсиз Айрлэнд Анлимитед Компани Замещенные циклоалкилом пиразолопиримидины, обладающие активностью против rsv
ES2957316T3 (es) * 2018-04-23 2024-01-17 Janssen Sciences Ireland Unlimited Co Compuestos heteroaromáticos que tienen actividad contra VSR
CN115666553A (zh) 2020-05-27 2023-01-31 轴向治疗公司 Tlr2调节剂化合物及其药物组合物和用途

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Also Published As

Publication number Publication date
JP2021522222A (ja) 2021-08-30
CN112004815A (zh) 2020-11-27
SG11202010323QA (en) 2020-11-27
WO2019206828A1 (en) 2019-10-31
MA52348A (fr) 2021-03-03
EA202092439A1 (ru) 2021-03-05
US11708369B2 (en) 2023-07-25
US20210094958A1 (en) 2021-04-01
EP3784667A1 (en) 2021-03-03
CA3095277A1 (en) 2019-10-31
AU2019260109A1 (en) 2020-09-17
AU2019260109B2 (en) 2023-07-13
EP3784667B1 (en) 2023-08-16
ES2957316T3 (es) 2024-01-17
KR20210005569A (ko) 2021-01-14
EP3784667C0 (en) 2023-08-16

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