MX2020010456A - Composiciones que comprenden polimeros reticulados con enlace a cationes. - Google Patents

Composiciones que comprenden polimeros reticulados con enlace a cationes.

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Publication number
MX2020010456A
MX2020010456A MX2020010456A MX2020010456A MX2020010456A MX 2020010456 A MX2020010456 A MX 2020010456A MX 2020010456 A MX2020010456 A MX 2020010456A MX 2020010456 A MX2020010456 A MX 2020010456A MX 2020010456 A MX2020010456 A MX 2020010456A
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MX
Mexico
Prior art keywords
compositions
base
crosslinked cation
polymer
equivalents
Prior art date
Application number
MX2020010456A
Other languages
English (en)
Inventor
Linda De Young
Stephen F Carroll
Original Assignee
Relypsa Inc
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Filing date
Publication date
Application filed by Relypsa Inc filed Critical Relypsa Inc
Publication of MX2020010456A publication Critical patent/MX2020010456A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/755—Polymers containing halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/04—Acids; Metal salts or ammonium salts thereof
    • C08F220/06—Acrylic acid; Methacrylic acid; Metal salts or ammonium salts thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
    • C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/1006—Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/102—Esters of polyhydric alcohols or polyhydric phenols of dialcohols, e.g. ethylene glycol di(meth)acrylate or 1,4-butanediol dimethacrylate

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  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Polymers & Plastics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
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Abstract

En líneas generales, la presente descripción hace referencia a composiciones que comprenden un polímero reticulado con enlaces a cationes que comprenden monómeros que contienen grupos ácido carboxílico y grupos que reducen el pKa que incluyen sustituyentes aceptores de electrones tales como átomos de haluro (por ejemplo, flúor) y una base, en el que el polímero opcionalmente contiene menos de alrededor de 20 000 ppm de cationes diferentes a hidrógeno y en el que la base se encuentra presente en una cantidad suficiente para proveer de alrededor de 0,2 equivalentes a alrededor de 0,95 equivalentes de base por equivalente de grupos ácido carboxílico en el polímero. La presente descripción también hace referencia a métodos para preparar dichas composiciones y a métodos para utilizarlas para tratar diversas enfermedades o trastornos.
MX2020010456A 2012-07-19 2015-01-16 Composiciones que comprenden polimeros reticulados con enlace a cationes. MX2020010456A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261673707P 2012-07-19 2012-07-19

Publications (1)

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MX2020010456A true MX2020010456A (es) 2020-10-20

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ID=49949269

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MX2015000810A MX2015000810A (es) 2012-07-19 2013-07-19 Composiciones que comprenden polímeros reticulados con enlace a cationes.
MX2020010456A MX2020010456A (es) 2012-07-19 2015-01-16 Composiciones que comprenden polimeros reticulados con enlace a cationes.

Family Applications Before (1)

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MX2015000810A MX2015000810A (es) 2012-07-19 2013-07-19 Composiciones que comprenden polímeros reticulados con enlace a cationes.

Country Status (14)

Country Link
US (1) US20150196585A1 (es)
EP (1) EP2874633A4 (es)
JP (3) JP6232062B2 (es)
KR (1) KR102211670B1 (es)
CN (2) CN105451746A (es)
AU (2) AU2013292350B9 (es)
BR (1) BR112015001230B1 (es)
CA (1) CA2879425A1 (es)
DE (1) DE112013003596T5 (es)
GB (1) GB2519479B (es)
HK (1) HK1203420A1 (es)
IN (1) IN2015DN01369A (es)
MX (2) MX2015000810A (es)
WO (1) WO2014015240A1 (es)

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WO2014015244A1 (en) * 2012-07-19 2014-01-23 Sorbent Therapeutics, Inc. Compositions comprising crosslinked cation-binding polymers
US10813946B2 (en) * 2012-10-08 2020-10-27 Vifor (International) Ltd. Potassium binding polymers for treating hypertension and hyperkalemia
US20170022314A1 (en) 2015-07-24 2017-01-26 Weyerhaeuser Nr Company Grafted crosslinked cellulose
US20170342383A1 (en) 2016-05-27 2017-11-30 Corning Incorporated Lithium disilicate glass-ceramic compositions and methods thereof
CN111417601A (zh) 2017-11-28 2020-07-14 康宁股份有限公司 化学强化的生物活性玻璃陶瓷
CN111433165A (zh) 2017-11-28 2020-07-17 康宁股份有限公司 高液相线粘度生物活性玻璃
CN111405913A (zh) 2017-11-28 2020-07-10 康宁股份有限公司 生物活性玻璃组合物和牙本质超敏性修复
EP3717428A1 (en) 2017-11-28 2020-10-07 Corning Incorporated Bioactive borate glass and methods thereof
CN108395497B (zh) * 2018-01-22 2021-03-30 中国科学院兰州化学物理研究所 紫外荧光型空间润滑油爬行屏障材料
CN111954657A (zh) * 2018-04-10 2020-11-17 阿科玛股份有限公司 官能含氟聚合物
WO2020097190A1 (en) * 2018-11-06 2020-05-14 Arizona Board Of Regents On Behalf Of The University Of Arizona Method of personalized treatment for cardiomyopathy and heart failure and associated diseases by measuring edema and cachexia/sarcopenia
JP2021192000A (ja) 2018-12-28 2021-12-16 フォルシアクラリオン・エレクトロニクス株式会社 経路案内方法、端末装置、経路案内システム及びプログラム
US20210186873A1 (en) * 2019-12-19 2021-06-24 Zaki Yusuf Gel compositions for mitigation of burn injuries, kits containing the gel compositions, and associated methods
US11807700B2 (en) * 2020-08-17 2023-11-07 Saudi Arabian Oil Company Electro-responsive hydrogel for reservoir and downhole application
WO2023035274A1 (en) * 2021-09-13 2023-03-16 Waterstone Pharmaceuticals(Wuhan) Co., Ltd. Polymer medicament for treating hyperkalemia and preparation method thereof
CN115570900B (zh) * 2022-09-28 2023-04-07 江西和烁丰新材料有限公司 一种环保型、可长久保存的热敏纸

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CA2879425A1 (en) 2014-01-23
JP6232062B2 (ja) 2017-11-15
AU2013292350B2 (en) 2018-08-09
IN2015DN01369A (es) 2015-07-03
GB2519479B (en) 2020-05-20
JP2019034956A (ja) 2019-03-07
JP2018024695A (ja) 2018-02-15
GB2519479A (en) 2015-04-22
JP6600062B2 (ja) 2019-10-30
BR112015001230B1 (pt) 2020-04-22
CN105451746A (zh) 2016-03-30
DE112013003596T5 (de) 2015-04-09
JP6423506B2 (ja) 2018-11-14
US20150196585A1 (en) 2015-07-16
MX2015000810A (es) 2015-06-05
BR112015001230A2 (pt) 2017-07-04
WO2014015240A1 (en) 2014-01-23
EP2874633A4 (en) 2016-06-29
AU2013292350B9 (en) 2018-08-23
KR102211670B1 (ko) 2021-02-02
CN110051686A (zh) 2019-07-26
JP2015528012A (ja) 2015-09-24
AU2013292350A1 (en) 2015-03-05
AU2018256550A1 (en) 2018-11-22
AU2018256550B2 (en) 2020-07-16
GB201502802D0 (en) 2015-04-08
HK1203420A1 (en) 2015-10-30
KR20150058164A (ko) 2015-05-28
EP2874633A1 (en) 2015-05-27

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